Search Results - "Alpha-synuclein"

Structure-function relationship of alpha-synuclein fibrillar polymorphs derived from distinct synucleinopathies.

Authors: Serdiuk T Redeker V Savistchenko J et al.

Source: Molecular systems biology [Mol Syst Biol] 2026 Jun; Vol. 22 (6), pp. 868-901. Date of Electronic Publication: 2026 Mar 11.

Publication Type: Journal Article

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE

Blm10/PA200-Activated 20S Proteasomes Promote α-Synuclein Degradation and Bypass Proteasome Inhibition in Parkinson's Disease Models.

Authors: Ali TT Zhornyak A Merghani M et al.

Source: Aging cell [Aging Cell] 2026 Jun; Vol. 25 (6), pp. e70566.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

Longevity Factor Klotho and Resistance to Cognitive Deficits in Individuals with Parkinson's Disease and in an α-Synuclein Mouse Model.

Authors: Luthra NS Bonham LW Moreno AJ et al.

Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2026 May 06; Vol. 46 (18). Date of Electronic Publication: 2026 May 06.

Publication Type: Journal Article

Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

Transcriptional dysregulation in the cerebellum triggered by oligodendroglial α-synucleinopathy: insights from a transgenic mouse into the early disease mechanisms of MSA.

Authors: Heras-Garvin A Fellner L Granata R et al.

Source: Journal of neural transmission (Vienna, Austria : 1996) [J Neural Transm (Vienna)] 2026 May; Vol. 133 (5), pp. 795-808. Date of Electronic Publication: 2025 Feb 15.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 9702341 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-1463 (Electronic) Linking ISSN: 03009564 NLM ISO Abbreviation: J Neural Transm (Vienna) Subsets: MEDLINE

Sphingolipidoses: expanding the spectrum of α-synucleinopathies.

Authors: Erskine D Bronowska AK Outeiro TF et al.

Source: Journal of neural transmission (Vienna, Austria : 1996) [J Neural Transm (Vienna)] 2026 May; Vol. 133 (5), pp. 809-821. Date of Electronic Publication: 2025 Apr 17.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 9702341 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-1463 (Electronic) Linking ISSN: 03009564 NLM ISO Abbreviation: J Neural Transm (Vienna) Subsets: MEDLINE

A Novel 3D Semi-Automated Full Quantification Technique for Detection of Intraneural Phospho-α-Synuclein in Skin Biopsies.

Authors: Lonczewski S Bader V Ortmann L et al.

Source: European journal of neurology [Eur J Neurol] 2026 Apr; Vol. 33 (4), pp. e70525.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 9506311 Publication Model: Print Cited Medium: Internet ISSN: 1468-1331 (Electronic) Linking ISSN: 13515101 NLM ISO Abbreviation: Eur J Neurol Subsets: MEDLINE

The Mechanism Underlying the Abnormal Expression of α-Synuclein in the Cortical Lesions of Patients With FCD Type IIb and TSC.

Authors: Zhang L Song JP Huang J et al.

Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2026 Apr; Vol. 32 (4), pp. e70893.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949 (Electronic) Linking ISSN: 17555930 NLM ISO Abbreviation: CNS Neurosci Ther Subsets: MEDLINE

The PET tracer [¹¹C]MODAG-005 targets alpha-synuclein aggregates in the brain.

Authors: Saw RS Haas S Schmidt F et al.

Source: Science translational medicine [Sci Transl Med] 2026 May 27; Vol. 18 (851), pp. eaec0813. Date of Electronic Publication: 2026 May 27.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Effects of α-synuclein pathology on synaptic dysfunction and clinical outcomes in normal aging.

Authors: Winer JR Plastini MJ Romero A et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 May; Vol. 22 (5), pp. e71455.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

Sex-Dependent Dynamics of Behavioural and Neuropathological Changes in an A53T Alpha-Synuclein Mouse Model of Parkinson's Disease.

Authors: Zubelzu M Bidgood R Murueta-Goyena A et al.

Source: Cellular and molecular neurobiology [Cell Mol Neurobiol] 2026 Mar 04; Vol. 46 (1). Date of Electronic Publication: 2026 Mar 04.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 8200709 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6830 (Electronic) Linking ISSN: 02724340 NLM ISO Abbreviation: Cell Mol Neurobiol Subsets: MEDLINE

Alpha-synuclein overexpression triggers divergent cellular responses and post-translational modifications in SH-SY5Y and ReNcell VM models.

Authors: Momand MUD Majerova P Mjartinova D et al.

Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Feb 21; Vol. 83 (1). Date of Electronic Publication: 2026 Feb 21.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

Enteric glia, neuropeptides, and Parkinson's: impacts of calcitonin gene-related peptide on gut alpha synuclein.

Authors: Templeton HN Lanser TB Tobet SA et al.

Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2026 Feb 01; Vol. 330 (2), pp. G73-G86. Date of Electronic Publication: 2025 Dec 16.

Publication Type: Journal Article

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1547 (Electronic) Linking ISSN: 01931857 NLM ISO Abbreviation: Am J Physiol Gastrointest Liver Physiol Subsets: MEDLINE

SNCA Overexpression Induces Apoptosis in Non-Small Cell Lung Cancer via Caspase-Dependent Signaling Pathways.

Authors: Leong YQ Koh RY Yap CG et al.

Source: BioMed research international [Biomed Res Int] 2026; Vol. 2026 (1), pp. e2222343.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101600173 Publication Model: Print Cited Medium: Internet ISSN: 2314-6141 (Electronic) NLM ISO Abbreviation: Biomed Res Int Subsets: MEDLINE

In Vivo Screen of Parkinson's Disease GWAS Risk Genes Identifies ARIH2 as a Novel Regulator of α-Synuclein Toxicity in Dopaminergic Neurons.

Authors: Armakola M Wilen AP Bustos BI et al.

Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2026 Mar 11; Vol. 46 (10). Date of Electronic Publication: 2026 Mar 11.

Publication Type: Journal Article

Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

SYNGR3 Accelerates α-Synuclein Aggregation and Neurodegeneration in Parkinson's Disease.

Authors: Wang X Yang J Wang Z et al.

Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2026 Mar; Vol. 32 (3), pp. e70842.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949 (Electronic) Linking ISSN: 17555930 NLM ISO Abbreviation: CNS Neurosci Ther Subsets: MEDLINE

Interaction of α-synuclein with DJ-1 in homodimer and L166P mutant monomer forms in Parkinson's disease: a molecular dynamics study.

Authors: Alipour M Hajipour-Verdom B Zali A et al.

Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2026 Feb; Vol. 44 (3), pp. 1558-1565. Date of Electronic Publication: 2025 Jan 08.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

Calcium overload induced mitochondrial and lysosomal dysfunction is regulated by Tousled-like kinase in a-synucleinopathy.

Authors: Gong F Cheng Q

Source: Cell death & disease [Cell Death Dis] 2026 Jan 08; Vol. 17 (1), pp. 10. Date of Electronic Publication: 2026 Jan 08.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

Alpha-synuclein quantitative seed amplification assay predicts conversion to dementia.

Authors: Bräuer S Sondermann V Schniewind I et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Jan; Vol. 22 (1), pp. e71167.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

Internalized SNCA/α-synuclein fibrils become truncated and resist degradation in neurons while glial cells rapidly degrade SNCA fibrils.

Authors: Karim MR Tiegs E Gasparini E et al.

Source: Autophagy [Autophagy] 2026 Jan; Vol. 22 (1), pp. 102-120. Date of Electronic Publication: 2025 Nov 12.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE

Sex-Specific Associations of α-Synuclein Pathology With Tau Accumulation.

Authors: Mak E Fought AJ Wiste HJ et al.

Corporate Authors: Mak E Fought AJ Wiste HJ et al.

Source: JAMA network open [JAMA Netw Open] 2026 Mar 02; Vol. 9 (3), pp. e260461. Date of Electronic Publication: 2026 Mar 02.

Publication Type: Journal Article

Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE