Search Results - "Amyloid beta-protein"

Behavior of neural networks in culture suggest that sporadic and genetic forms of Alzheimer's disease may not be equivalent.

Authors: Ma F Akolkar H Benosman R et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 May; Vol. 22 (5), pp. e71493.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE; In Process

Cell Type-Specific Expression of p16, p21, and p53 Reveals Age-Dependent Glial Senescence in the App^NL-G-F Mouse Model of Alzheimer's Disease.

Authors: Sweeney EM Abate G Bakker BRV et al.

Source: Aging cell [Aging Cell] 2026 Apr; Vol. 25 (4), pp. e70478.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

BDNF alters β-cleavage of APP and subcellular distribution of BACE1.

Authors: Hallam RD Foran G Fletcher NK et al.

Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2026 May 01; Vol. 330 (5), pp. C1296-C1308. Date of Electronic Publication: 2026 Mar 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

APP ubiquitination by VHL protein is essential for MVB sorting and lysosomal degradation.

Authors: Shan C Cong R Xu X et al.

Source: Journal of molecular cell biology [J Mol Cell Biol] 2026 Mar 02; Vol. 17 (8).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 101503669 Publication Model: Print Cited Medium: Internet ISSN: 1759-4685 (Electronic) Linking ISSN: 17594685 NLM ISO Abbreviation: J Mol Cell Biol Subsets: MEDLINE

sAPPα Inhibits Neurite Outgrowth in Primary Mouse Neurons via GABA B Receptor Subunit 1a.

Authors: Barber D Salinas-Salinas C Houmam S et al.

Source: ENeuro [eNeuro] 2026 Feb 18; Vol. 13 (2). Date of Electronic Publication: 2026 Feb 18 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 101647362 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2822 (Electronic) Linking ISSN: 23732822 NLM ISO Abbreviation: eNeuro Subsets: MEDLINE

APP Deficiency Ameliorates FAD Presenilin 1 F105C and A246E Mutations-induced Mitochondrial Dysfunction in Human Cortical Neurons.

Authors: Yen YH Yuan F Tang D et al.

Source: International journal of biological sciences [Int J Biol Sci] 2026 Feb 18; Vol. 22 (5), pp. 2720-2735. Date of Electronic Publication: 2026 Feb 18 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE

APP-mediated intracellular signaling rescues sleep impairment and blood-brain barrier leakage in Alzheimer's disease mouse model.

Authors: Puech C Sadanand A Coleman N et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Feb; Vol. 22 (2), pp. e71134.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

The Icelandic Mutation in the Murine APP Gene, mAPP^A673T, on Amyloid-β Plaque Burden in the 5×FAD Alzheimer Model.

Authors: Anschuetz A Listyono R Vorley T et al.

Source: Journal of integrative neuroscience [J Integr Neurosci] 2026 Jan 22; Vol. 25 (1), pp. 48581.

Publication Type: Journal Article

Journal Info: Publisher: IMR Press Country of Publication: Singapore NLM ID: 101156357 Publication Model: Print Cited Medium: Internet ISSN: 0219-6352 (Print) Linking ISSN: 02196352 NLM ISO Abbreviation: J Integr Neurosci Subsets: MEDLINE

APP Induces AICD-Mediated Autophagy-Dependent Axon Degeneration.

Authors: Luo J Qiu Y Pan Y et al.

Source: Aging cell [Aging Cell] 2026 Jan; Vol. 25 (1), pp. e70301. Date of Electronic Publication: 2025 Nov 23.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

Surgical removal of visceral adipose tissue has therapeutic benefit in male APP^NL-F mice.

Authors: McFadden SA Fang Y Quinn K et al.

Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2026 Mar 02; Vol. 17, pp. 1681801. Date of Electronic Publication: 2026 Mar 02 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

Levetiracetam prevents Aβ production through SV2a-dependent modulation of APP processing in Alzheimer's disease models.

Authors: Rao NR Santiago-Marrero I DeGulis O et al.

Source: Science translational medicine [Sci Transl Med] 2026 Feb 11; Vol. 18 (836), pp. eadp3984. Date of Electronic Publication: 2026 Feb 11.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Synaptic Vesicle Glycoprotein 2A Suppresses Amyloidogenesis Beyond Its Synaptic Role: A Novel Mechanism Disrupting BACE1 Binding and Altering APP Localization.

Authors: Wang X Zhang Q Zhang X et al.

Source: Aging cell [Aging Cell] 2026 Feb; Vol. 25 (2), pp. e70379.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

Early functional changes and plasma GFAP in Swedish families with Autosomal Dominant Alzheimer's disease mutations.

Authors: Luckett ES Zapater-Fajari M Almkvist O et al.

Source: Translational psychiatry [Transl Psychiatry] 2026 Jan 27; Vol. 16 (1), pp. 67. Date of Electronic Publication: 2026 Jan 27.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE

Amyloid precursor protein modulates cerebellar Purkinje cell activity and motor function through regulation of Nav1.6 currents.

Authors: Ji MJ Wu TX Tian C et al.

Source: PLoS biology [PLoS Biol] 2025 Nov 24; Vol. 23 (11), pp. e3003513. Date of Electronic Publication: 2025 Nov 24 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

Alpha-Ketoglutarate Ameliorates Synaptic Plasticity Deficits in APP/PS1 Mice Model of Alzheimer's Disease.

Authors: Navakkode S Kennedy BK

Source: Aging cell [Aging Cell] 2025 Nov; Vol. 24 (11), pp. e70235. Date of Electronic Publication: 2025 Sep 17.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

RABGAP1 is a sensor that facilitates the sorting and processing of amyloid precursor protein.

Authors: Eden J Kaufman JGG Pereira C et al.

Source: The EMBO journal [EMBO J] 2025 Oct; Vol. 44 (19), pp. 5443-5462. Date of Electronic Publication: 2025 Aug 26.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

Misclassification in memory modification in App^NL-G-F knock-in mouse model of Alzheimer's disease.

Authors: Huang ML Suzuki Y Sasaguri H et al.

Source: ELife [Elife] 2025 Nov 04; Vol. 14. Date of Electronic Publication: 2025 Nov 04.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Modeling presynaptic inhibition by the amyloid precursor protein demonstrates one potential mechanism for preventing runaway synaptic modification in Alzheimer's disease.

Authors: Barber D Hasselmo ME Rice HC

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Oct; Vol. 21 (10), pp. e70748.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

Discordant cerebrospinal fluid and positron emission tomography amyloid biomarkers in an APP mutation carrier presenting corticobasal syndrome.

Authors: Liu FT Li XY Lu JY et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Oct; Vol. 21 (10), pp. e70823.

Publication Type: Journal Article; Case Reports; Research Support, Non-U.S. Gov't

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

A protective role for APP in nuclear waste clearance via lysosomal exocytosis.

Authors: Dougnon G Otsuka T Nakamura Y et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jun 16; Vol. 123 (24), pp. e2524190123. Date of Electronic Publication: 2026 Jun 11.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE