Search Results - "Balk SP"

Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer.

Authors: Jiménez-Vacas JM Westaby D Figueiredo I et al.

Source: Nature communications [Nat Commun] 2025 Oct 08; Vol. 16 (1), pp. 8806. Date of Electronic Publication: 2025 Oct 08.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Epigenetic and oncogenic inhibitors converge to drive a metabolic catastrophe in castration-resistant prostate cancer.

Authors: Sahu R Enos M Sharma S et al.

Source: The Journal of clinical investigation [J Clin Invest] 2026 Jun 09. Date of Electronic Publication: 2026 Jun 09.

Publication Type: Journal Article

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

RNAs anchoring replication complex control initiation and firing of DNA replication.

Authors: Ummarino S Poluben L Ebralidze AK et al.

Source: Nature communications [Nat Commun] 2026 May 27. Date of Electronic Publication: 2026 May 27.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Immune Spatial Organization Predicts Distant Metastasis Risk in Aggressive Localized Prostate Cancer.

Authors: Yang DD Abdelnaser A Haas AJ et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2026 May 11. Date of Electronic Publication: 2026 May 11.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Wntless degradation mediated by CaMKII inhibition drives endoplasmic reticulum stress and apoptosis.

Authors: Gu Z Owiredu J Ersoy-Fazlioglu B et al.

Source: Cell reports [Cell Rep] 2026 Apr 11; Vol. 45 (4), pp. 117256. Date of Electronic Publication: 2026 Apr 11.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

BH3 mimetics targeting BCL-XL have efficacy in solid tumors with RB1 loss and replication stress.

Authors: Varkaris A Wang K Nouri M et al.

Source: Nature communications [Nat Commun] 2025 May 28; Vol. 16 (1), pp. 4931. Date of Electronic Publication: 2025 May 28.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

FOXJ1 mediates taxane resistance through regulation of microtubule dynamics.

Authors: Xie F Gjyrezi A Fein D et al.

Source: Nature communications [Nat Commun] 2026 Feb 14; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 14.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Preclinical Activity of the DLL3-Targeted T-cell Engager MK-6070 in Neuroendocrine Prostate Cancer.

Authors: Ku SY Manzar N Garcia MM et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2026 Feb 04; Vol. 25 (2), pp. 346-354.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

Lack of synergy between AR-targeted therapies and PARP inhibitors in homologous recombination-proficient prostate cancer.

Authors: Traphagen NA Wheeler E Li R et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Feb 03; Vol. 123 (5), pp. e2515790122. Date of Electronic Publication: 2026 Jan 27.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Developing therapeutic strategies to target MCL1 and BCLXL in lethal prostate cancer.

Authors: Westaby D Jiménez-Vacas JM Figueiredo I et al.

Source: IScience [iScience] 2025 Nov 10; Vol. 28 (12), pp. 113985. Date of Electronic Publication: 2025 Nov 10 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

Increased ErbB2 Signaling Is an Early Adaptation to Androgen Signaling Inhibition and Persists in Castration-Resistant Prostate Cancer.

Authors: Owiredu J Ersoy-Fazlioglu B Poluben L et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2025 Nov 03; Vol. 31 (21), pp. 4598-4610.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Androgen deprivation-mediated activation of AKT is enhanced in prostate cancer with TMPRSS2:ERG fusion.

Authors: Ma F Chen S Cecchi L et al.

Source: The Journal of clinical investigation [J Clin Invest] 2025 Oct 02; Vol. 135 (23). Date of Electronic Publication: 2025 Oct 02 (Print Publication: 2025).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways.

Authors: Hirani R Nandakumar S Zaman N et al.

Source: Cell reports [Cell Rep] 2025 Jun 24; Vol. 44 (6), pp. 115779. Date of Electronic Publication: 2025 May 30.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

Lack of synergy between AR targeted therapies and PARP inhibitors in homologous recombination-proficient prostate cancer.

Authors: Traphagen NA Wheeler E Li R et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jun 03. Date of Electronic Publication: 2025 Jun 03.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Heterogeneous Responses to High-Dose Testosterone in Castration-Resistant Prostate Cancer Tumors with Mixed Rb-Proficient and Rb-Deficient Cells.

Authors: Labaf M Han W Zhang S et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2025 May 02; Vol. 24 (5), pp. 772-783.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer.

Authors: Gui F Jiang B Jiang J et al.

Source: Science advances [Sci Adv] 2025 Apr 25; Vol. 11 (17), pp. eadu0847. Date of Electronic Publication: 2025 Apr 23.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

Influence of Neighborhood Social and Natural Environment on Prostate Tumor Histology in a Cohort of Male Health Professionals.

Authors: Iyer HS Vaselkiv JB Stopsack KH et al.

Source: American journal of epidemiology [Am J Epidemiol] 2023 Sep 01; Vol. 192 (9), pp. 1485-1498.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 7910653 Publication Model: Print Cited Medium: Internet ISSN: 1476-6256 (Electronic) Linking ISSN: 00029262 NLM ISO Abbreviation: Am J Epidemiol Subsets: MEDLINE

Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer.

Authors: Poluben L Nouri M Liang J et al.

Source: Cell reports [Cell Rep] 2025 Jan 28; Vol. 44 (1), pp. 115089. Date of Electronic Publication: 2024 Dec 21.

Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

RNAs anchoring replication complex control initiation and firing of DNA replication.

Authors: Ummarino S Poluben L Ebralidze AK et al.

Source: Research square [Res Sq] 2025 Jan 28. Date of Electronic Publication: 2025 Jan 28.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE

Invariant NKT cell-augmented GM-CSF-secreting tumor vaccine is effective in advanced prostate cancer model.

Authors: Varghese B Lynch L Vriend LE et al.

Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2022 Dec; Vol. 71 (12), pp. 2943-2955. Date of Electronic Publication: 2022 May 06.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE