Search Results - "Bates RH"

Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.

Authors: Davis SH Mathieson M Buchanan KI et al.

Source: Journal of medicinal chemistry [J Med Chem] 2025 Aug 14; Vol. 68 (15), pp. 16459-16482. Date of Electronic Publication: 2025 Aug 01.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Sanfetrinem, an oral β-lactam antibiotic repurposed for the treatment of tuberculosis.

Authors: Ramón-García S González Del Río R Arenaz-Callao MP et al.

Source: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy [Drug Resist Updat] 2025 May; Vol. 80, pp. 101213. Date of Electronic Publication: 2025 Feb 15.

Publication Type: Journal Article

Journal Info: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 9815369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2084 (Electronic) Linking ISSN: 13687646 NLM ISO Abbreviation: Drug Resist Updat Subsets: MEDLINE

Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs.

Authors: Green SR Davis SH Damerow S et al.

Source: Nature communications [Nat Commun] 2022 Oct 11; Vol. 13 (1), pp. 5992. Date of Electronic Publication: 2022 Oct 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Sanfetrinem, an oral β-lactam antibiotic repurposed for the treatment of tuberculosis.

Authors: Ramón-García S Del Río RG Arenaz-Callao MP et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 10. Date of Electronic Publication: 2024 Oct 10.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

αβ,α'β'-Diepoxyketones are mechanism-based inhibitors of nucleophilic cysteine enzymes.

Authors: de Munnik M Lithgow J Brewitz L et al.

Source: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2023 Oct 26; Vol. 59 (86), pp. 12859-12862. Date of Electronic Publication: 2023 Oct 26.

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: MEDLINE

High-throughput screen with the l,d-transpeptidase LdtMt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors.

Authors: de Munnik M Lang PA De Dios Anton F et al.

Source: Chemical science [Chem Sci] 2023 May 30; Vol. 14 (26), pp. 7262-7278. Date of Electronic Publication: 2023 May 30 (Print Publication: 2023).

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: eCollection Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE

Author Correction: Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.

Authors: Machutta CA Kollmann CS Lind KE et al.

Source: Nature communications [Nat Commun] 2018 Jul 13; Vol. 9, pp. 16227. Date of Electronic Publication: 2018 Jul 13.

Publication Type: Journal Article; Published Erratum

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: PubMed not MEDLINE

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.

Authors: Machutta CA Kollmann CS Lind KE et al.

Source: Nature communications [Nat Commun] 2017 Jul 17; Vol. 8, pp. 16081. Date of Electronic Publication: 2017 Jul 17.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment.

Authors: Nuermberger EL Martínez-Martínez MS Sanz O et al.

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Jun 21; Vol. 66 (6), pp. e0013222. Date of Electronic Publication: 2022 May 24.

Publication Type: Journal Article; Research Support, N.I.H., Intramural

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions.

Authors: Gold B Zhang J Quezada LL et al.

Source: ACS infectious diseases [ACS Infect Dis] 2022 Mar 11; Vol. 8 (3), pp. 557-573. Date of Electronic Publication: 2022 Feb 22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target.

Authors: Wilson C Ray P Zuccotto F et al.

Source: Journal of medicinal chemistry [J Med Chem] 2022 Jan 13; Vol. 65 (1), pp. 409-423. Date of Electronic Publication: 2021 Dec 15.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

The Tuberculosis Drug Accelerator at year 10: what have we learned?

Authors: Aldridge BB Barros-Aguirre D Barry CE 3rd et al.

Source: Nature medicine [Nat Med] 2021 Aug; Vol. 27 (8), pp. 1333-1337.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

Identification of KasA as the cellular target of an anti-tubercular scaffold.

Authors: Abrahams KA Chung CW Ghidelli-Disse S et al.

Source: Nature communications [Nat Commun] 2016 Sep 01; Vol. 7, pp. 12581. Date of Electronic Publication: 2016 Sep 01.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery.

Authors: Rebollo-Lopez MJ Lelièvre J Alvarez-Gomez D et al.

Source: PloS one [PLoS One] 2015 Dec 07; Vol. 10 (12), pp. e0142293. Date of Electronic Publication: 2015 Dec 07 (Print Publication: 2015).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis.

Authors: Ballell L Bates RH Young RJ et al.

Source: ChemMedChem [ChemMedChem] 2013 Feb; Vol. 8 (2), pp. 313-21. Date of Electronic Publication: 2013 Jan 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection.

Authors: Poce G Bates RH Alfonso S et al.

Source: PloS one [PLoS One] 2013; Vol. 8 (2), pp. e56980. Date of Electronic Publication: 2013 Feb 21.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Optimization of Hydantoins as Potent Antimycobacterial Decaprenylphosphoryl-β-d-Ribose Oxidase (DprE1) Inhibitors.

Authors: Balabon O Pitta E Rogacki MK et al.

Source: Journal of medicinal chemistry [J Med Chem] 2020 May 28; Vol. 63 (10), pp. 5367-5386. Date of Electronic Publication: 2020 May 13.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Bosutinib prevents vascular leakage by reducing focal adhesion turnover and reinforcing junctional integrity.

Authors: Botros L Pronk MCA Juschten J et al.

Source: Journal of cell science [J Cell Sci] 2020 May 14; Vol. 133 (9). Date of Electronic Publication: 2020 May 14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE

Exploring the SAR of the β-Ketoacyl-ACP Synthase Inhibitor GSK3011724A and Optimization around a Genotoxic Metabolite.

Authors: Cunningham F Esquivias J Fernández-Menéndez R et al.

Source: ACS infectious diseases [ACS Infect Dis] 2020 May 08; Vol. 6 (5), pp. 1098-1109. Date of Electronic Publication: 2020 Mar 20.

Publication Type: Journal Article

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

Novel Pyrazole-Containing Compounds Active against Mycobacterium tuberculosis.

Authors: Poce G Consalvi S Venditti G et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Sep 18; Vol. 10 (10), pp. 1423-1429. Date of Electronic Publication: 2019 Sep 18 (Print Publication: 2019).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE