Search Results - "Beumer JH"

Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU).

Authors: Beumer JH Parise RA Newman EM et al.

Source: Cancer Chemotherapy & Pharmacology. Jul2008, Vol. 62 Issue 2, p363-368. 6p.

URL: 31998879

Biomarkers of phenethyl isothiocyanate-mediated mammary cancer chemoprevention in a clinically relevant mouse model.

Authors: Singh SV Kim SH Sehrawat A et al.

Source: JNCI: Journal of the National Cancer Institute. 2012 Aug 1, Vol. 104 Issue 16, p1228-1239. 12p.

Phase I trial of the combination of flavopiridol and imatinib mesylate in patients with Bcr-Abl+ hematological malignancies.

Authors: Bose P Perkins EB Honeycut C et al.

Source: Cancer Chemotherapy & Pharmacology. Jun2012, Vol. 69 Issue 6, p1657-1667. 11p.

Phase I pharmacokinetic study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor vatalanib (PTK787) plus imatinib and hydroxyurea for malignant glioma.

Authors: Reardon DA Egorin MJ Desjardins A et al.

Source: Cancer (0008543X). 5/15/2009, Vol. 115 Issue 10, p2188-2198. 11p.

Phase 2 study of cabozantinib (XL184) with nivolumab and ipilimumab for the treatment of poorly differentiated neuroendocrine carcinomas (ETCTN10315).

Authors: Mandl A Chen R Das S et al.

Source: The oncologist [Oncologist] 2026 May 08; Vol. 31 (6).

Publication Type: Journal Article; Clinical Trial, Phase II

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE

Association of SULT2A1 Locus With Abiraterone Clearance in the Alliance A031201: Randomized Phase III Study of Enzalutamide Compared With Enzalutamide Plus Abiraterone for Metastatic Castration-Resistant Prostate Cancer.

Authors: Norton N Larson NB Jenkins GD et al.

Source: Clinical and translational science [Clin Transl Sci] 2025 Dec; Vol. 18 (12), pp. e70425.

Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Comparative Study

Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

Phase Ib study of berzosertib, carboplatin, gemcitabine, and pembrolizumab in patients with squamous nonsmall lung cancer (ETCTN 10313).

Authors: Villaruz LC Schluger B Wang H et al.

Source: The oncologist [Oncologist] 2025 Nov 11; Vol. 30 (11).

Publication Type: Journal Article; Clinical Trial, Phase I

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE

Clinical and translational study of ivosidenib plus nivolumab in advanced solid tumors harboring IDH1 mutations.

Authors: Nguyen MK Jelinek M Singh A et al.

Source: The oncologist [Oncologist] 2025 Nov 11; Vol. 30 (11).

Publication Type: Journal Article; Clinical Trial, Phase II

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE

Fibroblast growth factor receptor inhibition for succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 2 trial.

Authors: Merriam P Morrow JJ Mazzola E et al.

Source: Nature medicine [Nat Med] 2026 Jun; Vol. 32 (6), pp. 2191-2200. Date of Electronic Publication: 2026 May 26.

Publication Type: Journal Article; Clinical Trial, Phase II

Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

Transient ATR inhibition following ionizing radiation enhances immune-mediated antitumor response and survival.

Authors: Deppas J Kiesel BF Vendetti FP et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 28. Date of Electronic Publication: 2026 May 28.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

ATR kinase inhibitors induce mitochondrial fission in CD8 ⁺ T cells and impair immune memory in vivo.

Authors: Vendetti FP Sclafani CR Zhang Y et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 26. Date of Electronic Publication: 2026 May 26.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Enhancing triapine treatment: strategies for dose optimization and methemoglobin level mitigation.

Authors: Lee H Dunn A Taylor SE et al.

Source: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2026 May 20; Vol. 96 (1). Date of Electronic Publication: 2026 May 20.

Publication Type: Journal Article; Clinical Trial, Phase I

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE

Pharmacokinetics of venetoclax in a patient after whipple pancreaticoduodenectomy.

Authors: Le TV Dunn A Holleran JL et al.

Source: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2026 Apr 29; Vol. 96 (1). Date of Electronic Publication: 2026 Apr 29.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE; In Process

Phase 1 studies of the indenoisoquinolines LMP776 and LMP744 in patients with solid tumors and lymphomas.

Authors: O'Sullivan Coyne G Kummar S Rubinstein LV et al.

Source: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2025 May 29; Vol. 95 (1), pp. 58. Date of Electronic Publication: 2025 May 29.

Publication Type: Clinical Trial, Phase I; Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE

A phase 1 study of berzosertib (M6620, VX-970) in combination with cisplatin and radiation in patients with locally advanced head and neck squamous cell carcinoma (ETCTN 9950).

Authors: Bhatia A Chen Z Zhang Y et al.

Source: Cancer [Cancer] 2026 Mar 15; Vol. 132 (6), pp. e70346.

Publication Type: Journal Article; Clinical Trial, Phase I

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0374236 Publication Model: Print Cited Medium: Internet ISSN: 1097-0142 (Electronic) Linking ISSN: 0008543X NLM ISO Abbreviation: Cancer Subsets: MEDLINE

Phase I trial of ATR inhibitor elimusertib with FOLFIRI in advanced or metastatic gastrointestinal malignancies (ETCTN 10406).

Authors: Krishnamurthy A Wang H Rhee JC et al.

Source: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2025 Jan 22; Vol. 95 (1), pp. 27. Date of Electronic Publication: 2025 Jan 22.

Publication Type: Journal Article; Clinical Trial, Phase I

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE

Dose finding, bioavailability, and PK-PD of oral triapine with concurrent chemoradiation for locally advanced cervical cancer and vaginal cancer (ETCTN 9892).

Authors: Taylor SE Behr S Cooper KL et al.

Source: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2024 Dec 14; Vol. 95 (1), pp. 4. Date of Electronic Publication: 2024 Dec 14.

Publication Type: Journal Article; Clinical Trial, Phase I

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE

Quantitation of the DNA-dependent protein kinase inhibitor peposertib (M3814) and metabolite in human plasma by LC-MS/MS.

Authors: Christner SM Parise RA Bakkenist CJ et al.

Source: Biomedical chromatography : BMC [Biomed Chromatogr] 2024 Dec; Vol. 38 (12), pp. e6024. Date of Electronic Publication: 2024 Oct 08.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

A phase 1 study of orally administered 5-fluoro-2'-deoxycytidine with tetrahydrouridine in patients with refractory solid tumors.

Authors: Chen AP Kummar S Rubinstein L et al.

Source: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2025 Dec 22; Vol. 96 (1), pp. 1. Date of Electronic Publication: 2025 Dec 22.

Publication Type: Journal Article; Clinical Trial, Phase I

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE

Letrozole, abemaciclib and metformin in endometrial cancer: a non-randomized phase 2 trial.

Authors: Konstantinopoulos PA Zhou N Penson RT et al.

Source: Nature communications [Nat Commun] 2025 Dec 03; Vol. 17 (1), pp. 395. Date of Electronic Publication: 2025 Dec 03.

Publication Type: Journal Article; Clinical Trial, Phase II

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE