Search Results - "Boobis, Alan"

A new approach to the classification of carcinogenicity.

Authors: Doe, John E. Boobis, Alan R. Cohen, Samuel M. et al.

Source: Archives of Toxicology. Sep2022, Vol. 96 Issue 9, p2419-2428. 10p.

The codification of hazard and its impact on the hazard versus risk controversy.

Authors: Doe, John E. Boobis, Alan R. Cohen, Samuel M. et al.

Source: Archives of Toxicology. Nov2021, Vol. 95 Issue 11, p3611-3621. 11p.

Characterising vaping products in the United Kingdom: an analysis of Tobacco Products Directive notification data.

Authors: Nyakutsikwa, Blessing Britton, John Bogdanovica, Ilze et al.

Source: Addiction. Sep2021, Vol. 116 Issue 9, p2521-2528. 8p. 3 Charts, 1 Graph.

Subjects: Electronic cigarettes, Research methodology, Harm reduction, Descriptive statistics, Tobacco products, Smoking

Geographic Terms: United Kingdom

Mode of action approach supports a lack of carcinogenic potential of six organic UV filters.

Authors: Cohen, Samuel M. Boobis, Alan R. Jacobson-Kram, David et al.

Source: Critical Reviews in Toxicology. Feb2025, Vol. 55 Issue 2, p248-284. 37p.

Retraction of Williams et al. (2000) does not affect the conclusions of the 2016 FAO/WHO JMPR evaluation of glyphosate.

Authors: Moretto, Angelo Boobis, Alan R.

Source: Regulatory Toxicology & Pharmacology: RTP. Jun2026, Vol. 168, pN.PAG-N.PAG. 1p.

Hazard identification, classification, and risk assessment of carcinogens: too much or too little? – Report of an ECETOC workshop.

Authors: Felter, Susan P. Boobis, Alan R. Botham, Philip A. et al.

Source: Critical Reviews in Toxicology. Jan2020, Vol. 50 Issue 1, p72-95. 24p. 1 Diagram, 3 Charts.

Harmonized methodology to assess chronic dietary exposure to residues from compounds used as pesticide and veterinary drug.

Authors: Arcella, Davide Boobis, Alan Cressey, Peter et al.

Source: Critical Reviews in Toxicology. Jan2019, Vol. 49 Issue 1, p1-10. 10p. 1 Diagram, 6 Charts.

Influence of Operating Parameters on the Biodegradation of Steroid Estrogens and Nonylphenolic Compounds during Biological Wastewater Treatment Processes.

Authors: Koh, Yoong K. K. Chiu, Tze Y. Boobis, Alan R.

Source: Environmental Science & Technology; September 1 2009, Vol. 43 Issue 17, p6646-6654, 9p

Characterizing chronic and acute health risks of residues of veterinary drugs in food: latest methodological developments by the joint FAO/WHO expert committee on food additives.

Authors: Boobis, Alan Cerniglia, Carl Chicoine, Alan et al.

Source: Critical Reviews in Toxicology. Nov2017, Vol. 47 Issue 10, p885-903. 15p. 5 Charts.

Origin of the TTC values for compounds that are genotoxic and/or carcinogenic and an approach for their re-evaluation.

Authors: Boobis, Alan Brown, Paul Cronin, Mark Timothy David et al.

Source: Critical Reviews in Toxicology. Sep2017, Vol. 47 Issue 8, p705-732. 23p. 1 Diagram, 4 Charts.

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E2F1-Mediated FOS Induction in Arsenic Trioxide--Induced Cellular Transformation: Effects of Global H3K9 Hypoacetylation and Promoter-Specific Hyperacetylation in Vitro.

Authors: Rahman, Sunniyat Housein, Zjwan Dabrowska, Aleksandra et al.

Source: Environmental Health Perspectives. May2015, Vol. 123 Issue 5, p484-492. 9p. 4 Graphs.

Subject Terms: *Arsenic, Biological assay, Cell culture, Flow cytometry, Gene expression, Metabolism, Oncogenes, Polymerase chain reaction, Research funding, Western immunoblotting, Data analysis software, Descriptive statistics, Precipitin tests, In vitro studies

Critical analysis of literature on low-dose synergy for use in screening chemical mixtures for risk assessment.

Authors: Boobis, Alan Budinsky, Robert Collie, Shanna et al.

Source: Critical Reviews in Toxicology. May2011, Vol. 41 Issue 5, p369-383. 15p. 1 Diagram, 1 Chart, 2 Graphs.

Managing the challenge of chemically reactive metabolites in drug development.

Authors: Park, B. Kevin Boobis, Alan Clarke, Stephen et al.

Source: Nature Reviews Drug Discovery. Apr2011, Vol. 10 Issue 4, p292-306. 15p. 3 Diagrams, 1 Chart.

Mode of Action Considerations in the Quantitative Assessment of Tumour Responses in the Liver.

Authors: Boobis, Alan R.¹ a.boobis@imperial.ac.uk

Source: Basic & Clinical Pharmacology & Toxicology. Mar2010, Vol. 106 Issue 3, p173-179. 7p. 2 Diagrams.

Guidance for the classification of carcinogens under the Globally Harmonised System of Classification and Labelling of Chemicals (GHS).

Authors: McGregor, Douglas Boobis, Alan Binaglia, Marco et al.

Source: Critical Reviews in Toxicology. Mar2010, Vol. 40 Issue 3, p245-285. 41p. 2 Diagrams, 14 Charts.

Drug interactions.

Authors: Boobis, Alan Watelet, Jean-Baptiste Whomsley, Rhys et al.

Source: Drug Metabolism Reviews. Aug2009, Vol. 41 Issue 3, p486-527. 42p. 13 Diagrams, 11 Charts.

Increased Expression of Histone Proteins during Estrogen-Mediated Cell Proliferation.

Authors: Zheying Zhu Edwards, Robert J. Boobis, Alan R.

Source: Environmental Health Perspectives. Jun2009, Vol. 117 Issue 6, p928-934. 7p. 1 Diagram, 4 Charts, 2 Graphs.

Subject Terms: *Biomarkers, *Mass spectrometry, Histones, Cell proliferation, Estrogen receptors, Polyacrylamide gel electrophoresis, Cell lines, Bisphenol A, Estrogen

IPCS Framework for Analyzing the Relevance of a Noncancer Mode of Action for Humans.

Authors: Boobis, Alan R. Doe, John E. Heinrich-Hirsch, Barbara et al.

Source: Critical Reviews in Toxicology. Feb2008, Vol. 38 Issue 2, p87-96. 10p. 1 Diagram.

Testicular Dysgenesis Syndrome and the Estrogen Hypothesis: A Quantitative Meta-Analysis.

Authors: Martin, Olwenn V. Shialis, Tassos Lester, John N. et al.

Source: Environmental Health Perspectives. Feb2008, Vol. 116 Issue 2, p149-157. 9p. 8 Charts, 7 Graphs.

Subject Terms: *Endocrine disruptors, Testis, Effect of chemicals on human reproduction, Genitalia, Selective estrogen receptor modulators, Meta-analysis, Diethylstilbestrol, Cancer risk factors, Hypospadias, Cryptorchism, Oral contraceptives