Search Results - "Brightbill HD"

TGFb signaling instructs a conserved fibrosis-associated cell state marked by LRRC15.

Authors: Shyer JA Wehbe F Davidson CD et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 May 26; Vol. 123 (21), pp. e2536550123. Date of Electronic Publication: 2026 May 20.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Combined antagonism of Oncostatin M (OSM) and Interleukin 6 (IL-6) provides both anti-fibrotic and anti-inflammatory benefit in pulmonary fibrosis.

Authors: Ratsimandresy RA Doran E Dengler HS et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jan 13. Date of Electronic Publication: 2026 Jan 13.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Therapeutic effects of FGF21 mimetic bFKB1 on MASH and atherosclerosis in Ldlr-/-.Leiden mice.

Authors: Inia JA Attema J de Ruiter C et al.

Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Oct 31; Vol. 38 (20), pp. e70087.

Publication Type: Journal Article

Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

Diffusion tensor MRI is sensitive to fibrotic injury in a mouse model of oxalate-induced chronic kidney disease.

Authors: Virgincar RS Wong AK Barck KH et al.

Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2024 Aug 01; Vol. 327 (2), pp. F235-F244. Date of Electronic Publication: 2024 Jun 13.

Publication Type: Journal Article

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE

YAP/TAZ activity in PDGFRα-expressing alveolar fibroblasts modulates AT2 proliferation through Wnt4.

Authors: Song JY Wehbe F Wong AK et al.

Source: Cell reports [Cell Rep] 2025 May 27; Vol. 44 (5), pp. 115645. Date of Electronic Publication: 2025 May 05.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

IL-23 signaling is not an important driver of liver inflammation and fibrosis in murine non-alcoholic steatohepatitis models.

Authors: Heredia JE Sorenson C Flanagan S et al.

Source: PloS one [PLoS One] 2022 Sep 15; Vol. 17 (9), pp. e0274582. Date of Electronic Publication: 2022 Sep 15 (Print Publication: 2022).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

IL-4-induced SOX9 confers lineage plasticity to aged adult lung stem cells.

Authors: Cai XT Jia M Heigl T et al.

Source: Cell reports [Cell Rep] 2024 Aug 27; Vol. 43 (8), pp. 114569. Date of Electronic Publication: 2024 Jul 31.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis.

Authors: Sun T Huang Z Liang WC et al.

Source: Science translational medicine [Sci Transl Med] 2021 Aug 04; Vol. 13 (605).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Isoform-selective TGF-β3 inhibition for systemic sclerosis.

Authors: Sun T Vander Heiden JA Gao X et al.

Source: Med (New York, N.Y.) [Med] 2024 Feb 09; Vol. 5 (2), pp. 132-147.e7. Date of Electronic Publication: 2024 Jan 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101769215 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-6340 (Electronic) Linking ISSN: 26666340 NLM ISO Abbreviation: Med Subsets: MEDLINE

The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells.

Authors: Corzo CA Varfolomeev E Setiadi AF et al.

Source: Science signaling [Sci Signal] 2020 Jun 02; Vol. 13 (634). Date of Electronic Publication: 2020 Jun 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

Targeted alveolar regeneration with Frizzled-specific agonists.

Authors: Nabhan AN Webster JD Adams JJ et al.

Source: Cell [Cell] 2023 Jul 06; Vol. 186 (14), pp. 2995-3012.e15. Date of Electronic Publication: 2023 Jun 14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design.

Authors: Crawford JJ Feng J Brightbill HD et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2023 Jun 01; Vol. 89, pp. 129277. Date of Electronic Publication: 2023 Apr 25.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus.

Authors: Brightbill HD Suto E Blaquiere N et al.

Source: Nature communications [Nat Commun] 2018 Jan 12; Vol. 9 (1), pp. 179. Date of Electronic Publication: 2018 Jan 12.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

BMP1 is not required for lung fibrosis in mice.

Authors: Ma HY N'Diaye EN Caplazi P et al.

Source: Scientific reports [Sci Rep] 2022 Mar 31; Vol. 12 (1), pp. 5466. Date of Electronic Publication: 2022 Mar 31.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Author Correction: NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.

Authors: Gu M Zhou X Sohn JH et al.

Source: Nature immunology [Nat Immunol] 2021 Apr; Vol. 22 (4), pp. 530.

Publication Type: Published Erratum

Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE; PubMed not MEDLINE

NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.

Authors: Gu M Zhou X Sohn JH et al.

Source: Nature immunology [Nat Immunol] 2021 Feb; Vol. 22 (2), pp. 193-204. Date of Electronic Publication: 2021 Jan 04.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE

A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production.

Authors: Simpson LJ Patel S Bhakta NR et al.

Source: Nature immunology [Nat Immunol] 2014 Dec; Vol. 15 (12), pp. 1162-70. Date of Electronic Publication: 2014 Nov 02.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE

Addendum: IgE+ memory B cells and plasma cells generated through a germinal-center pathway.

Authors: Talay O Yan D Brightbill HD et al.

Source: Nature immunology [Nat Immunol] 2013 Dec; Vol. 14 (12), pp. 1302-4.

Publication Type: Journal Article

Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE

IgE⁺ memory B cells and plasma cells generated through a germinal-center pathway.

Authors: Talay O Yan D Brightbill HD et al.

Source: Nature immunology [Nat Immunol] 2012 Feb 26; Vol. 13 (4), pp. 396-404. Date of Electronic Publication: 2012 Feb 26.

Publication Type: Journal Article

Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE

Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice.

Authors: Brightbill HD Jeet S Lin Z et al.

Source: The Journal of clinical investigation [J Clin Invest] 2010 Jun; Vol. 120 (6), pp. 2218-29. Date of Electronic Publication: 2010 May 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE