Search Results - "Carruthers VB"

An in vivo fitness gene of Toxoplasma, MIC11, is essential for PLP1-mediated egress from host cells.

Authors: Tachibana Y Gu X Sasai M et al.

Source: Nature communications [Nat Commun] 2026 Apr 04; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 04.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Improvements in potency and selectivity of triazine nitrile inhibitors targeting Toxoplasma gondii cathepsin L for the treatment of latent toxoplasmosis.

Authors: Borel TJ 2nd Hitchens JR Kaur H et al.

Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2026 Jul; Vol. 138, pp. 118643. Date of Electronic Publication: 2026 Apr 06.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Impact of equilibrative nucleoside transporters on Toxoplasma gondii infection and differentiation.

Authors: Messina G Goerner A Bennett C et al.

Source: MBio [mBio] 2025 Nov 12; Vol. 16 (11), pp. e0220725. Date of Electronic Publication: 2025 Sep 30.

Publication Type: Journal Article

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

Translation initiation factor eIF1.2 promotes Toxoplasma stage conversion by regulating levels of key differentiation factors.

Authors: Wang F Holmes MJ Hong HJ et al.

Source: Nature communications [Nat Commun] 2024 May 23; Vol. 15 (1), pp. 4385. Date of Electronic Publication: 2024 May 23.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

A conserved complex of microneme proteins mediates rhoptry discharge in Toxoplasma.

Authors: Valleau D Sidik SM Godoy LC et al.

Source: The EMBO journal [EMBO J] 2023 Dec 01; Vol. 42 (23), pp. e113155. Date of Electronic Publication: 2023 Oct 27.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

Metabolic adaptability and nutrient scavenging in Toxoplasma gondii: insights from ingestion pathway-deficient mutants.

Authors: Rimple PA Olafsson EB Markus BM et al.

Source: MSphere [mSphere] 2025 Apr 29; Vol. 10 (4), pp. e0101124. Date of Electronic Publication: 2025 Apr 02.

Publication Type: Journal Article

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101674533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-5042 (Electronic) Linking ISSN: 23795042 NLM ISO Abbreviation: mSphere Subsets: MEDLINE

The vacuolar iron transporter mediates iron detoxification in Toxoplasma gondii.

Authors: Aghabi D Sloan M Gill G et al.

Source: Nature communications [Nat Commun] 2023 Jun 20; Vol. 14 (1), pp. 3659. Date of Electronic Publication: 2023 Jun 20.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

The multifaceted interactions between pathogens and host ESCRT machinery.

Authors: Rivera-Cuevas Y Carruthers VB

Source: PLoS pathogens [PLoS Pathog] 2023 May 04; Vol. 19 (5), pp. e1011344. Date of Electronic Publication: 2023 May 04 (Print Publication: 2023).

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Stable endocytic structures navigate the complex pellicle of apicomplexan parasites.

Authors: Koreny L Mercado-Saavedra BN Klinger CM et al.

Source: Nature communications [Nat Commun] 2023 Apr 15; Vol. 14 (1), pp. 2167. Date of Electronic Publication: 2023 Apr 15.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Toxoplasma gondii PROP1 is critical for autophagy and parasite viability during chronic infection.

Authors: Thaprawat P Wang F Chalasani S et al.

Source: MSphere [mSphere] 2025 Mar 25; Vol. 10 (3), pp. e0082924. Date of Electronic Publication: 2025 Feb 21.

Publication Type: Journal Article

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101674533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-5042 (Electronic) Linking ISSN: 23795042 NLM ISO Abbreviation: mSphere Subsets: MEDLINE

Toxoplasma induced cytokine release syndrome is critically dependent on the expression of pore-forming Perforin-Like Protein-1.

Authors: Gregg B Guerra AJ Raverty SA et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Mar 17. Date of Electronic Publication: 2025 Mar 17.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

A membrane lipid signature unravels the dynamic landscape of group 1 innate lymphoid cells across the health-disease continuum.

Authors: Frey HC Sun X Oudeif F et al.

Source: IScience [iScience] 2025 Feb 17; Vol. 28 (3), pp. 112043. Date of Electronic Publication: 2025 Feb 17 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

The Toxoplasma plant-like vacuolar compartment (PLVAC).

Authors: Stasic AJ Moreno SNJ Carruthers VB et al.

Source: The Journal of eukaryotic microbiology [J Eukaryot Microbiol] 2022 Nov; Vol. 69 (6), pp. e12951. Date of Electronic Publication: 2022 Oct 27.

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 9306405 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-7408 (Electronic) Linking ISSN: 10665234 NLM ISO Abbreviation: J Eukaryot Microbiol Subsets: MEDLINE

Attenuated Toxoplasma gondii enhances the antitumor efficacy of anti-PD1 antibody by altering the tumor microenvironment in a pancreatic cancer mouse model.

Authors: Bahwal SA Chen JJ E L et al.

Source: Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2022 Oct; Vol. 148 (10), pp. 2743-2757. Date of Electronic Publication: 2022 May 12.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7902060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1335 (Electronic) Linking ISSN: 01715216 NLM ISO Abbreviation: J Cancer Res Clin Oncol Subsets: MEDLINE

Adaptations and metabolic evolution of myzozoan protists across diverse lifestyles and environments.

Authors: Waller RF Carruthers VB

Source: Microbiology and molecular biology reviews : MMBR [Microbiol Mol Biol Rev] 2024 Dec 18; Vol. 88 (4), pp. e0019722. Date of Electronic Publication: 2024 Oct 10.

Publication Type: Journal Article; Review

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 9706653 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5557 (Electronic) Linking ISSN: 10922172 NLM ISO Abbreviation: Microbiol Mol Biol Rev Subsets: MEDLINE

Metabolic Adaptability and Nutrient Scavenging in Toxoplasma gondii: Insights from Ingestion Pathway-Deficient Mutants.

Authors: Rimple PA Olafsson EB Markus BM et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 27. Date of Electronic Publication: 2024 Nov 27.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Kinase function of TgTKL1 is essential for its role in Toxoplasma propagation and pathogenesis.

Authors: Ali DH Anandakrishnan R Carruthers VB et al.

Source: MSphere [mSphere] 2024 Nov 21; Vol. 9 (11), pp. e0077924. Date of Electronic Publication: 2024 Oct 30.

Publication Type: Journal Article

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101674533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-5042 (Electronic) Linking ISSN: 23795042 NLM ISO Abbreviation: mSphere Subsets: MEDLINE

Apicomplexan Pore-Forming Toxins.

Authors: Carruthers VB; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA; email: vcarruth@umich.edu.

Source: Annual review of microbiology [Annu Rev Microbiol] 2024 Nov; Vol. 78 (1), pp. 277-291. Date of Electronic Publication: 2024 Nov 07.

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural

Journal Info: Publisher: Annual Reviews Country of Publication: United States NLM ID: 0372370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-3251 (Electronic) Linking ISSN: 00664227 NLM ISO Abbreviation: Annu Rev Microbiol Subsets: MEDLINE

Toxoplasma gondii excretion of glycolytic products is associated with acidification of the parasitophorous vacuole during parasite egress.

Authors: Huynh MH Carruthers VB

Source: PLoS pathogens [PLoS Pathog] 2022 May 05; Vol. 18 (5), pp. e1010139. Date of Electronic Publication: 2022 May 05 (Print Publication: 2022).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

TgATG9 is required for autophagosome biogenesis and maintenance of chronic infection in Toxoplasma gondii.

Authors: Thaprawat P Zhang Z Rentchler EC et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 09. Date of Electronic Publication: 2024 Jul 09.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE