Search Results - "Chaconas G"

Making the best of a sticky situation: Infection-mediated endothelial activation promotes new interactions with adhesins of the host-adapted Lyme disease spirochete.

Authors: Olmedo DA Tan X Scott C et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 21. Date of Electronic Publication: 2026 Feb 21.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Structure analysis of the telomere resolvase from the Lyme disease spirochete Borrelia garinii reveals functional divergence of its C-terminal domain.

Authors: Semper C Watanabe N Karimullina E et al.

Source: Nucleic acids research [Nucleic Acids Res] 2024 Aug 12; Vol. 52 (14), pp. 8431-8442.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Transendothelial migration of the Lyme disease spirochete involves spirochete internalization as an intermediate step through a transcellular pathway that involves Cdc42 and Rac1.

Authors: Alvarez-Olmedo D Kamaliddin C Verhey TB et al.

Source: Microbiology spectrum [Microbiol Spectr] 2025 Feb 04; Vol. 13 (2), pp. e0222124. Date of Electronic Publication: 2024 Dec 27.

Publication Type: Journal Article

Journal Info: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE

DNA lipid nanoparticle vaccine targeting outer surface protein C affords protection against homologous Borrelia burgdorferi needle challenge in mice.

Authors: Pfeifle A Thulasi Raman SN Lansdell C et al.

Source: Frontiers in immunology [Front Immunol] 2023 Mar 16; Vol. 14, pp. 1020134. Date of Electronic Publication: 2023 Mar 16 (Print Publication: 2023).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

VlsE, the nexus for antigenic variation of the Lyme disease spirochete, also mediates early bacterial attachment to the host microvasculature under shear force.

Authors: Tan X Lin YP Pereira MJ et al.

Source: PLoS pathogens [PLoS Pathog] 2022 May 23; Vol. 18 (5), pp. e1010511. Date of Electronic Publication: 2022 May 23 (Print Publication: 2022).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Transendothelial migration of the Lyme disease spirochete involves spirochete internalization as an intermediate step through a transcellular pathway that involves Cdc42 and Rac1.

Authors: Alvarez-Olmedo D Kamaliddin C Verhey TB et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 10. Date of Electronic Publication: 2024 Sep 10.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

The Lyme disease spirochete can hijack the host immune system for extravasation from the microvasculature.

Authors: Tan X Petri B DeVinney R et al.

Source: Molecular microbiology [Mol Microbiol] 2021 Aug; Vol. 116 (2), pp. 498-515. Date of Electronic Publication: 2021 May 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8712028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2958 (Electronic) Linking ISSN: 0950382X NLM ISO Abbreviation: Mol Microbiol Subsets: MEDLINE

MINNO: An Open Source Software for Refining Metabolic Networks and Investigating Complex Network Activity Using Empirical Metabolomics Data.

Authors: Mandwal A Bishop SL Castellanos M et al.

Source: Analytical chemistry [Anal Chem] 2024 Feb 27; Vol. 96 (8), pp. 3382-3388. Date of Electronic Publication: 2024 Feb 15.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE

Choreography of Lyme Disease Spirochete Adhesins To Promote Vascular Escape.

Authors: Tan X Castellanos M Chaconas G

Source: Microbiology spectrum [Microbiol Spectr] 2023 Aug 17; Vol. 11 (4), pp. e0125423. Date of Electronic Publication: 2023 May 31.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE

Strain-specific joint invasion and colonization by Lyme disease spirochetes is promoted by outer surface protein C.

Authors: Lin YP Tan X Caine JA et al.

Source: PLoS pathogens [PLoS Pathog] 2020 May 15; Vol. 16 (5), pp. e1008516. Date of Electronic Publication: 2020 May 15 (Print Publication: 2020).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Metabolic Interactive Nodular Network for Omics (MINNO): Refining and investigating metabolic networks based on empirical metabolomics data.

Authors: Mandwal A Bishop SL Castellanos M et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 17. Date of Electronic Publication: 2023 Jul 17.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Antigenic variation in the Lyme spirochete: detailed functional assessment of recombinational switching at vlsE in the JD1 strain of Borrelia burgdorferi.

Authors: Verhey TB Castellanos M Chaconas G

Source: Molecular microbiology [Mol Microbiol] 2019 Mar; Vol. 111 (3), pp. 750-763. Date of Electronic Publication: 2019 Jan 31.

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8712028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2958 (Electronic) Linking ISSN: 0950382X NLM ISO Abbreviation: Mol Microbiol

A Borrelia burgdorferi mini-vls system that undergoes antigenic switching in mice: investigation of the role of plasmid topology and the long inverted repeat.

Authors: Castellanos M Verhey TB Chaconas G

Source: Molecular microbiology [Mol Microbiol] 2018 Sep; Vol. 109 (5), pp. 710-721. Date of Electronic Publication: 2018 Sep 09.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8712028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2958 (Electronic) Linking ISSN: 0950382X NLM ISO Abbreviation: Mol Microbiol Subsets: MEDLINE

Analysis of recombinational switching at the antigenic variation locus of the Lyme spirochete using a novel PacBio sequencing pipeline.

Authors: Verhey TB Castellanos M Chaconas G

Source: Molecular microbiology [Mol Microbiol] 2018 May; Vol. 108 (4), pp. 461.

Publication Type: Journal Article; Published Erratum

Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8712028 Publication Model: Print Cited Medium: Internet ISSN: 1365-2958 (Electronic) Linking ISSN: 0950382X NLM ISO Abbreviation: Mol Microbiol Subsets: PubMed not MEDLINE

Analysis of recombinational switching at the antigenic variation locus of the Lyme spirochete using a novel PacBio sequencing pipeline.

Authors: Verhey TB Castellanos M Chaconas G

Source: Molecular microbiology [Mol Microbiol] 2018 Jan; Vol. 107 (1), pp. 104-115. Date of Electronic Publication: 2017 Nov 17.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8712028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2958 (Electronic) Linking ISSN: 0950382X NLM ISO Abbreviation: Mol Microbiol Subsets: MEDLINE

The Putative Endonuclease Activity of MutL Is Required for the Segmental Gene Conversion Events That Drive Antigenic Variation of the Lyme Disease Spirochete.

Authors: Castellanos M Verhey TB Goldstein M et al.

Source: Frontiers in microbiology [Front Microbiol] 2022 May 19; Vol. 13, pp. 888494. Date of Electronic Publication: 2022 May 19 (Print Publication: 2022).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101548977 Publication Model: eCollection Cited Medium: Print ISSN: 1664-302X (Print) Linking ISSN: 1664302X NLM ISO Abbreviation: Front Microbiol Subsets: PubMed not MEDLINE

Intravital Imaging of Vascular Transmigration by the Lyme Spirochete: Requirement for the Integrin Binding Residues of the B. burgdorferi P66 Protein.

Authors: Kumar D Ristow LC Shi M et al.

Source: PLoS pathogens [PLoS Pathog] 2015 Dec 18; Vol. 11 (12), pp. e1005333. Date of Electronic Publication: 2015 Dec 18 (Print Publication: 2015).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Live Imaging.

Authors: Chaconas G Moriarty TJ Skare J et al.

Source: Current issues in molecular biology [Curr Issues Mol Biol] 2021; Vol. 42, pp. 385-408. Date of Electronic Publication: 2020 Dec 12.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100931761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-3045 (Electronic) Linking ISSN: 14673037 NLM ISO Abbreviation: Curr Issues Mol Biol Subsets: MEDLINE

Suggested role for G4 DNA in recombinational switching at the antigenic variation locus of the Lyme disease spirochete.

Authors: Walia R Chaconas G

Source: PloS one [PLoS One] 2013; Vol. 8 (2), pp. e57792. Date of Electronic Publication: 2013 Feb 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

HrpA, an RNA helicase involved in RNA processing, is required for mouse infectivity and tick transmission of the Lyme disease spirochete.

Authors: Salman-Dilgimen A Hardy PO Radolf JD et al.

Source: PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (12), pp. e1003841. Date of Electronic Publication: 2013 Dec 19.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE