Search Results - "Chimeric proteins"

Immunoinformatics-based design of artificial chimeric proteins as universal vaccine candidates against foot-and-mouth disease virus serotypes A, O, and SAT2.

Authors: Elrashedy, Alyaa Nayel, Mohamed Salama, Akram et al.

Source: Scientific Reports. 6/9/2026, Vol. 16 Issue 1, p1-34. 34p.

Bioinformatics‐Driven Design of Fusion Recombinant Protein (EgFABP1‐EgTeg) for Enhanced Immunodiagnosis of Hydatid Cysts.

Authors: Mehdi, Abolfazl Masoumi Koushk Motedayyen, Hossein Arbabi, Mohsen et al.

Source: Immunity, Inflammation & Disease. May2026, Vol. 14 Issue 5, p1-14. 14p.

Design and Characterization of Recombinant and Chimeric BoNT/A Neurotoxins with Receptor-Binding Domain Grafting.

Authors: Pan, Sihan Ye, Yuanzhi Li, Yang et al.

Source: Toxins. May2026, Vol. 18 Issue 5, p205. 18p.

Downregulation of the Transglutaminase 2–NF-κB Inflammatory Axis by a Fusion Protein of Cementoin and Secretory Leukocyte Protease Inhibitor Reduces Corneal Angiogenesis.

Authors: Salica, Juan Pablo Potilinski, María Constanza Ortiz, Gustavo et al.

Source: International Journal of Molecular Sciences. Apr2026, Vol. 27 Issue 7, p3247. 23p.

Epithelial polarization by the planar cell polarity complex is exclusively non–cell autonomous.

Authors: Basta, Lena P. Joyce, Bradley W. Posfai, Eszter et al.

Source: Science. 3/21/2025, Vol. 387 Issue 6740, p1-13. 13p.

A Simplified Strategy for Nanobody Production and Use Based on Functional GST-Nanobody Fusion Proteins.

Authors: Burgos, Agustín A. Rivera-Dictter, Andrés Mendoza-Soto, Pablo et al.

Source: Biomolecules (2218-273X). Feb2026, Vol. 16 Issue 2, p306. 20p.

Advances in Preclinical Research Models of ROS1 Fusion Proteins in Non-Small Cell Lung Cancer.

Authors: Allababidi, Taoufik Saygideger, Yasemin

Source: European Journal of Biology. Dec2025, Vol. 84 Issue 2, p220-230. 11p.

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Expanding salivary biomarker detection by creating a synthetic neuraminic acid sensor via chimeragenesis.

Authors: Verzino, Samuel J. Priyev, Sharona A. Estrada, Valeria A. Sánchez et al.

Source: Applied & Environmental Microbiology. May2026, Vol. 92 Issue 5, p1-23. 23p.

Subjects: Chimeric proteins, Sialic acids, Protein engineering, Biosensors, Cancer diagnosis, Fluorescent probes, Saliva analysis, Synthetic biology

Engineering chimeric signaling proteins for microbial whole-cell biosensors: from design to deployment.

Authors: Özer Bergman, Güniz Mecacci, Sonia Martins dos Santos, Vitor A.P. et al.

Source: Trends in Biotechnology. Apr2026, Vol. 44 Issue 4, p975-990. 16p.

Subjects: Chimeric proteins, Biosensors, Allosteric regulation, Signals & signaling, Environmental monitoring, Protein engineering

Tumor Homing Chimeric Peptide Rhomboids to Improve Photodynamic Performance by Inhibiting Therapy-Upregulated Cyclooxygenase-2.

Authors: Zhang W Yu BX Chen XY et al.

Source: Small (Weinheim an der Bergstrasse, Germany) [Small] 2024 Jul; Vol. 20 (28), pp. e2309882. Date of Electronic Publication: 2024 Feb 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101235338 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1613-6829 (Electronic) Linking ISSN: 16136810 NLM ISO Abbreviation: Small Subsets: MEDLINE

Synthesis of Chirally Chimeric Protein Nanoparticle Vaccines via Mirror‐Image Spy Chemistry.

Authors: Kou, Songzi Sun, Chenbo Chen, Weitao et al.

Source: Angewandte Chemie International Edition. Aug2025, Vol. 64 Issue 34, p1-11. 11p.

Aberrant splicing in neuroblastoma generates RNA-fusion transcripts and provides vulnerability to spliceosome inhibitors.

Authors: Shi Y Yuan J Rraklli V et al.

Source: Nucleic acids research [Nucleic Acids Res] 2021 Mar 18; Vol. 49 (5), pp. 2509-2521.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

In silico and in vitro evaluation of a PE38 and Nb‐based recombinant immunotoxin targeting the GRP78 receptor in cancer cells.

Authors: Khoshbakht, Mona Forghanifard, Mohammad Mahdi Aghamollaei, Hossein et al.

Source: Biotechnology & Applied Biochemistry. Apr2025, Vol. 72 Issue 2, p484-497. 14p.

Subjects: Chimeric proteins, Cell receptors, Cytotoxins, Recombinant proteins, Cancer cells

An N‐acetyltransferase‐MAPK fusion protein modulates developmental reprogramming in Physcomitrium patens.

Authors: de Luxán‐Hernández, Cloe Ammitsøe, Thomas J. Kanne, Jakob V. et al.

Source: New Phytologist. Jul2026, Vol. 251 Issue 1, p321-339. 19p.

Subjects: Chimeric proteins, Post-translational modification, Physiology, Mitogen-activated protein kinases, Mosses, Acetyltransferases, Cell differentiation, Metabolic reprogramming

Interdomain communication suppressing high intrinsic ATPase activity of Sse1 is essential for its co-disaggregase activity with Ssa1.

Authors: Kumar V Peter JJ Sagar A et al.

Source: The FEBS journal [FEBS J] 2020 Feb; Vol. 287 (4), pp. 671-694. Date of Electronic Publication: 2019 Sep 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

Engineered IgA-Fc fusion protein with bioactive nanobody neutralizes SARS-CoV-2 variants with mucosal delivery potential.

Authors: Golonka, Rachel M. Intravaia, Lauren E. Shaqra, Ala M. et al.

Source: Journal of Biological Chemistry. Mar2026, Vol. 302 Issue 3, p1-11. 11p.

Subjects: Chimeric proteins, Immunoglobulins, SARS-CoV-2, Antiviral agents, Intranasal administration, COVID-19 treatment, SARS-CoV-2 Omicron variant

Engineered Prx-LCA2 fusion protein restores oxidative skin damage via enhanced intracellular peroxidase delivery.

Authors: Liu, Di Zhan, Yafen Qu, Jiaqi et al.

Source: AMB Express. 6/18/2025, Vol. 15 Issue 1, p1-16. 16p.

The Trivalent Recombinant Chimeric Proteins Containing Immunodominant Fragments of Toxoplasma gondii SAG1 and SAG2 Antigens in Their Core—A Good Diagnostic Tool for Detecting IgG Antibodies in Human Serum Samples.

Authors: Ferra, Bartłomiej Tomasz Chyb, Maciej Skwarecka, Marta et al.

Source: International Journal of Molecular Sciences. Jun2025, Vol. 26 Issue 12, p5621. 18p.

Cas9‐Rep fusion tethers donor DNAin vivo and boosts the efficiency of HDR‐mediated genome editing.

Authors: Zhou, Zhentao Xiao, Jiahui Yin, Shuai et al.

Source: Plant Biotechnology Journal. Jun2025, Vol. 23 Issue 6, p2006-2017. 12p.