Search Results - "Clegg LE"

Efficacy and safety of sipavibart for prevention of COVID-19 in individuals who are immunocompromised (SUPERNOVA): a randomised, controlled, double-blind, phase 3 trial.

Authors: Haidar G Thomas S Loubet P et al.

Corporate Authors: Haidar G Thomas S Loubet P et al.

Source: The Lancet. Infectious diseases [Lancet Infect Dis] 2025 Jul; Vol. 25 (7), pp. 813-826. Date of Electronic Publication: 2025 Feb 24.

Publication Type: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Multicenter Study

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4457 (Electronic) Linking ISSN: 14733099 NLM ISO Abbreviation: Lancet Infect Dis Subsets: MEDLINE

RSV Neutralizing Antibodies Following Nirsevimab and Palivizumab Dosing.

Authors: Wilkins D Wählby Hamrén U Chang Y et al.

Source: Pediatrics [Pediatrics] 2024 Nov 01; Vol. 154 (5).

Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Clinical Trial, Phase III; Multicenter Study

Journal Info: Publisher: American Academy of Pediatrics Country of Publication: United States NLM ID: 0376422 Publication Model: Print Cited Medium: Internet ISSN: 1098-4275 (Electronic) Linking ISSN: 00314005 NLM ISO Abbreviation: Pediatrics Subsets: MEDLINE

Assessing reproducibility and utility of clustering of patients with type 2 diabetes and established CV disease (SAVOR -TIMI 53 trial).

Authors: Aoki Y Hamrén B Clegg LE et al.

Source: PloS one [PLoS One] 2021 Nov 19; Vol. 16 (11), pp. e0259372. Date of Electronic Publication: 2021 Nov 19 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Serum AZD7442 (tixagevimab-cilgavimab) concentrations and in vitroIC50 values predict SARS-CoV-2 neutralising antibody titres.

Authors: Clegg LE Stepanov O Matthews S et al.

Source: Clinical & translational immunology [Clin Transl Immunology] 2024 Jun 13; Vol. 13 (6), pp. e1517. Date of Electronic Publication: 2024 Jun 13 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons Australia, Ltd. on behalf of Australasian Society for Immunology Inc Country of Publication: Australia NLM ID: 101638268 Publication Model: eCollection Cited Medium: Print ISSN: 2050-0068 (Print) Linking ISSN: 20500068 NLM ISO Abbreviation: Clin Transl Immunology Subsets: PubMed not MEDLINE

Accelerating therapeutics development during a pandemic: population pharmacokinetics of the long-acting antibody combination AZD7442 (tixagevimab/cilgavimab) in the prophylaxis and treatment of COVID-19.

Authors: Clegg LE Stepanov O Schmidt H et al.

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2024 May 02; Vol. 68 (5), pp. e0158723. Date of Electronic Publication: 2024 Mar 27.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

Potassium homeostasis and therapeutic intervention with sodium zirconium cyclosilicate: A model-informed drug development case study.

Authors: Clegg LE Chu L Nagard M et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Feb; Vol. 13 (2), pp. 296-307. Date of Electronic Publication: 2023 Dec 04.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

Cardiovascular and renal safety of metformin in patients with diabetes and moderate or severe chronic kidney disease: Observations from the EXSCEL and SAVOR-TIMI 53 cardiovascular outcomes trials.

Authors: Clegg LE Jing Y Penland RC et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2021 May; Vol. 23 (5), pp. 1101-1110. Date of Electronic Publication: 2021 Feb 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Effect of once-weekly exenatide on estimated glomerular filtration rate slope depends on baseline renal risk: A post hoc analysis of the EXSCEL trial.

Authors: van der Aart-van der Beek AB Clegg LE Penland RC et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2020 Dec; Vol. 22 (12), pp. 2493-2498. Date of Electronic Publication: 2020 Sep 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Prediction and validation of exenatide risk marker effects on progression of renal disease: Insights from EXSCEL.

Authors: Idzerda NMA Clegg LE Hernandez AF et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2020 May; Vol. 22 (5), pp. 798-806. Date of Electronic Publication: 2020 Feb 03.

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Effects of exenatide and open-label SGLT2 inhibitor treatment, given in parallel or sequentially, on mortality and cardiovascular and renal outcomes in type 2 diabetes: insights from the EXSCEL trial.

Authors: Clegg LE Penland RC Bachina S et al.

Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2019 Oct 22; Vol. 18 (1), pp. 138. Date of Electronic Publication: 2019 Oct 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE

Reduction of Cardiovascular Risk and Improved Estimated Glomerular Filtration Rate by SGLT2 Inhibitors, Including Dapagliflozin, Is Consistent Across the Class: An Analysis of the Placebo Arm of EXSCEL.

Authors: Clegg LE Heerspink HJL Penland RC et al.

Source: Diabetes care [Diabetes Care] 2019 Feb; Vol. 42 (2), pp. 318-326. Date of Electronic Publication: 2018 Dec 06.

Publication Type: Journal Article; Multicenter Study; Pragmatic Clinical Trial; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 7805975 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-5548 (Electronic) Linking ISSN: 01495992 NLM ISO Abbreviation: Diabetes Care

Arterialized collateral capillaries progress from nonreactive to capable of increasing perfusion in an ischemic arteriolar tree.

Authors: Gouin KH 3rd Hellstrom SK Clegg LE et al.

Source: Microcirculation (New York, N.Y. : 1994) [Microcirculation] 2018 Apr; Vol. 25 (3), pp. e12438.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 9434935 Publication Model: Print Cited Medium: Internet ISSN: 1549-8719 (Electronic) Linking ISSN: 10739688 NLM ISO Abbreviation: Microcirculation Subsets: MEDLINE

A computational analysis of pro-angiogenic therapies for peripheral artery disease.

Authors: Clegg LE Mac Gabhann F

Source: Integrative biology : quantitative biosciences from nano to macro [Integr Biol (Camb)] 2018 Jan 22; Vol. 10 (1), pp. 18-33.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101478378 Publication Model: Print Cited Medium: Internet ISSN: 1757-9708 (Electronic) Linking ISSN: 17579694 NLM ISO Abbreviation: Integr Biol (Camb) Subsets: MEDLINE

A computational analysis of in vivo VEGFR activation by multiple co-expressed ligands.

Authors: Clegg LE Mac Gabhann F

Source: PLoS computational biology [PLoS Comput Biol] 2017 Mar 20; Vol. 13 (3), pp. e1005445. Date of Electronic Publication: 2017 Mar 20 (Print Publication: 2017).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

Systems biology of the microvasculature.

Authors: Clegg LE Mac Gabhann F

Source: Integrative biology : quantitative biosciences from nano to macro [Integr Biol (Camb)] 2015 May; Vol. 7 (5), pp. 498-512. Date of Electronic Publication: 2015 Apr 02.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101478378 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-9708 (Electronic) Linking ISSN: 17579694 NLM ISO Abbreviation: Integr Biol (Camb) Subsets: MEDLINE

Systems Pharmacology of VEGF165b in Peripheral Artery Disease.

Authors: Clegg LE Ganta VC Annex BH et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2017 Dec; Vol. 6 (12), pp. 833-844. Date of Electronic Publication: 2017 Nov 28.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

Molecular mechanism matters: Benefits of mechanistic computational models for drug development.

Authors: Clegg LE Mac Gabhann F

Source: Pharmacological research [Pharmacol Res] 2015 Sep; Vol. 99, pp. 149-54. Date of Electronic Publication: 2015 Jun 18.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1186 (Electronic) Linking ISSN: 10436618 NLM ISO Abbreviation: Pharmacol Res Subsets: MEDLINE