Search Results - "Coombs CC"

Patient-reported outcomes among patients with mantle cell lymphoma or chronic lymphocytic leukemia receiving pirtobrutinib in the BRUIN phase 1/2 study: final analysis.

Authors: Coombs CC Woyach JA Brown JR et al.

Source: Current medical research and opinion [Curr Med Res Opin] 2025 Dec; Vol. 41 (12), pp. 2323-2338. Date of Electronic Publication: 2026 Jan 30.

Publication Type: Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0351014 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-4877 (Electronic) Linking ISSN: 03007995 NLM ISO Abbreviation: Curr Med Res Opin Subsets: MEDLINE

Patient-reported outcomes in BRUIN CLL-321: A randomized phase 3 trial comparing pirtobrutinib to investigators choice of idelalisib plus rituximab or bendamustine plus rituximab in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma in the post-cBTKi setting.

Authors: Ghia P Rossi D Ferrant E et al.

Source: Journal of geriatric oncology [J Geriatr Oncol] 2026 Jun 17; Vol. 17 (6), pp. 103024. Date of Electronic Publication: 2026 Jun 17.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101534770 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-4076 (Electronic) Linking ISSN: 18794068 NLM ISO Abbreviation: J Geriatr Oncol Subsets: MEDLINE

Docirbrutinib is a pan-mutant BTK inhibitor and inhibits B-cell receptor signaling in chronic lymphocytic leukemia cells in preclinical and early clinical investigations.

Authors: Timofeeva N Herrera B Fujiwara H et al.

Source: Blood cancer journal [Blood Cancer J] 2026 May 07. Date of Electronic Publication: 2026 May 07.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE

Treatment Decision-making for Individuals with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) in the United States.

Authors: Coombs CC LeBlanc TW Winfree KB et al.

Source: Acta haematologica [Acta Haematol] 2026 May 07, pp. 1-21. Date of Electronic Publication: 2026 May 07.

Publication Type: Journal Article

Journal Info: Publisher: Karger Country of Publication: Switzerland NLM ID: 0141053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9662 (Electronic) Linking ISSN: 00015792 NLM ISO Abbreviation: Acta Haematol Subsets: MEDLINE

What's hidden in plain sight? Impact of clonal hematopoiesis on the risk and progression of nonhematologic cancers.

Authors: Martínez JC Coombs CC

Source: Haematologica [Haematologica] 2026 May 01; Vol. 111 (5), pp. 1552-1565. Date of Electronic Publication: 2025 Sep 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE

Clinical strategies for lymphoma management: Recommendations from the Bridging the Gaps in Leukemia, Lymphoma, and Multiple Myeloma Consensus Conference 2025.

Authors: Danilov AV Coombs CC Phillips T et al.

Source: Cancer [Cancer] 2026 Apr 15; Vol. 132 (8), pp. e70389.

Publication Type: Journal Article; Consensus Statement

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0374236 Publication Model: Print Cited Medium: Internet ISSN: 1097-0142 (Electronic) Linking ISSN: 0008543X NLM ISO Abbreviation: Cancer Subsets: MEDLINE

Pirtobrutinib, a highly selective, noncovalent (reversible) BTKi in R/R marginal zone lymphoma: phase 1/2 BRUIN study.

Authors: Patel K Vose JM Nasta SD et al.

Source: Blood advances [Blood Adv] 2026 Apr 14; Vol. 10 (7), pp. 2441-2451.

Publication Type: Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I

Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

Perspectives on Current Challenges and Emerging Approaches for Lymphoma Management From the First Bridging the Gaps in Leukemia, Lymphoma, and Multiple Myeloma Conference.

Authors: Danilov AV Sauter C Phillips T et al.

Source: Clinical lymphoma, myeloma & leukemia [Clin Lymphoma Myeloma Leuk] 2025 Jun; Vol. 25 (6), pp. e366-e373. Date of Electronic Publication: 2025 Jan 13.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101525386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2152-2669 (Electronic) Linking ISSN: 21522669 NLM ISO Abbreviation: Clin Lymphoma Myeloma Leuk Subsets: MEDLINE

Pirtobrutinib Versus Ibrutinib in Treatment-Naïve and Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Authors: Woyach JA Qiu L Grosicki S et al.

Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2026 Feb 20; Vol. 44 (6), pp. 476-485. Date of Electronic Publication: 2025 Dec 07.

Publication Type: Journal Article; Randomized Controlled Trial; Comparative Study; Multicenter Study; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE

BETting on the future: BET inhibition for patients with lymphoma.

Authors: Voorhees TJ Coombs CC

Source: Med (New York, N.Y.) [Med] 2026 Jan 09; Vol. 7 (1), pp. 100955.

Publication Type: Journal Article; Comment

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101769215 Publication Model: Print Cited Medium: Internet ISSN: 2666-6340 (Electronic) Linking ISSN: 26666340 NLM ISO Abbreviation: Med Subsets: MEDLINE

Treatment Effectiveness of Venetoclax-Based Therapy After Bruton Tyrosine Kinase Inhibitors in Chronic Lymphocytic Leukemia: An International Real-World Study.

Authors: Ghosh N Eyre TA Brown JR et al.

Source: American journal of hematology [Am J Hematol] 2025 Mar; Vol. 100 (3), pp. 511-515. Date of Electronic Publication: 2024 Dec 19.

Publication Type: Letter

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE; In Process

Safety of Extended Pirtobrutinib Exposure in Relapsed and/or Refractory B-Cell Malignancies.

Authors: Roeker LE Coombs CC Shah NN et al.

Source: Acta haematologica [Acta Haematol] 2025; Vol. 148 (2), pp. 180-197. Date of Electronic Publication: 2024 Jun 05.

Publication Type: Journal Article

Journal Info: Publisher: Karger Country of Publication: Switzerland NLM ID: 0141053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9662 (Electronic) Linking ISSN: 00015792 NLM ISO Abbreviation: Acta Haematol Subsets: MEDLINE

Interindividual variability in CYP3A-mediated venetoclax metabolism in vitro and in vivo in patients with chronic lymphocytic leukemia.

Authors: Lee J Beers JL Cheng I et al.

Source: Clinical and translational science [Clin Transl Sci] 2024 Dec; Vol. 17 (12), pp. e70106.

Publication Type: Journal Article

Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

Pirtobrutinib, a highly selective, noncovalent (reversible) BTKi in R/R follicular lymphoma: phase 1/2 BRUIN study.

Authors: Shah NN Zinzani PL Wang M et al.

Source: Blood advances [Blood Adv] 2025 Dec 09; Vol. 9 (23), pp. 5954-5964.

Publication Type: Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I; Multicenter Study

Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

R-DA-EPOCH Versus DA-EPOCH-R: Impact of Chemoimmunotherapy Sequencing on Treatment Outcomes in Patients With Diffuse Large B-Cell Lymphoma.

Authors: Lee BJ Griffin SP Doh J et al.

Source: Clinical lymphoma, myeloma & leukemia [Clin Lymphoma Myeloma Leuk] 2025 Dec; Vol. 25 (12), pp. e1014-e1021. Date of Electronic Publication: 2025 Jun 23.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101525386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2152-2669 (Electronic) Linking ISSN: 21522669 NLM ISO Abbreviation: Clin Lymphoma Myeloma Leuk Subsets: MEDLINE

Pirtobrutinib in the treatment of chronic lymphocytic leukemia or small lymphocytic lymphoma.

Authors: Ibrahim S Pham N Sahni A et al.

Source: Future oncology (London, England) [Future Oncol] 2025 Nov; Vol. 21 (26), pp. 3435-3445. Date of Electronic Publication: 2025 Oct 03.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101256629 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8301 (Electronic) Linking ISSN: 14796694 NLM ISO Abbreviation: Future Oncol Subsets: MEDLINE

Frontline Therapy of CLL-Changing Treatment Paradigms.

Authors: Coombs CC; University of California Irvine, 200 S. Manchester Avenue, Suite 400, Room 428, ZOT 4061, Orange, Irvine, CA, 92868, USA. coombsc@hs.uci.edu.

Source: Current hematologic malignancy reports [Curr Hematol Malig Rep] 2024 Apr; Vol. 19 (2), pp. 65-74. Date of Electronic Publication: 2024 Feb 10.

Publication Type: Journal Article; Review

Journal Info: Publisher: Current Science Country of Publication: United States NLM ID: 101262565 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-822X (Electronic) Linking ISSN: 15588211 NLM ISO Abbreviation: Curr Hematol Malig Rep Subsets: MEDLINE

Are we closer to a standard of care for Richter's syndrome? Novel treatments on the horizon.

Authors: Pham N Coombs CC O'Brien S

Source: Expert review of hematology [Expert Rev Hematol] 2024 Apr-May; Vol. 17 (4-5), pp. 117-126. Date of Electronic Publication: 2024 May 09.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101485942 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-4094 (Electronic) Linking ISSN: 17474094 NLM ISO Abbreviation: Expert Rev Hematol Subsets: MEDLINE

Feasibility of Bruton's Tyrosine Kinase Inhibitor Discontinuation in Chronic Lymphocytic Leukemia: The Patient Perspective.

Authors: Stephens DM Stewart C Avruch L et al.

Source: Clinical lymphoma, myeloma & leukemia [Clin Lymphoma Myeloma Leuk] 2025 Sep; Vol. 25 (9), pp. e663-e667. Date of Electronic Publication: 2025 May 16.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101525386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2152-2669 (Electronic) Linking ISSN: 21522669 NLM ISO Abbreviation: Clin Lymphoma Myeloma Leuk Subsets: MEDLINE

Erratum: Phase III Trial of Pirtobrutinib Versus Idelalisib/Rituximab or Bendamustine/Rituximab in Covalent Bruton Tyrosine Kinase Inhibitor-Pretreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-321).

Authors: Sharman JP Munir T Grosicki S et al.

Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2025 Sep; Vol. 43 (25), pp. 2841. Date of Electronic Publication: 2025 Jul 29.

Publication Type: Journal Article; Published Erratum

Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE; In Process