Search Results - "Crofton, Kevin M."

Cumulative Author Index for Volumes 29–341.

Source: Fundamental & Applied Toxicology. 1996, Vol. 34 Issue 2, p307-310. 4p.

A developmental neurotoxicity adverse outcome pathway (DNT‐AOP) with voltage gate sodium channel (VGSC) inhibition as a molecular initiating event (MiE).

Authors: Crofton, Kevin M. Paparella, Martin Price, Anna et al.

Source: EFSA Journal. Aug2024, Vol. 22 Issue 8, p1-19. 19p.

Cumulative Author Index for Volumes 41–461.

Source: Toxicological Sciences. 1998, Vol. 46 Issue 2, p423-426. 4p.

Putative adverse outcome pathways relevant to neurotoxicity.

Authors: Bal-Price, Anna Crofton, Kevin M. Sachana, Magdalini et al.

Source: Critical Reviews in Toxicology. Jan2015, Vol. 45 Issue 1, p83-91. 9p. 1 Chart.

Comment on "On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens".

Authors: Houck, Keith A. Judson, Richard S. Knudsen, Thomas B. et al.

Source: Environmental Health Perspectives. Jan2017, Vol. 125 Issue 1, pA8-A11. 4p. 1 Chart.

Subject Terms: *Toxicity testing, *Physiology, Obesity risk factors, Adipogenesis, Biotransformation (Metabolism), Cell differentiation, Adipose tissue physiology, Obesity

An Empirical Approach to Sufficient Similarity: Combining Exposure Data and Mixtures Toxicology Data.

Authors: Marshall, Scott Gennings, Chris Teuschler, Linda K. et al.

Source: Risk Analysis: An International Journal. Sep2013, Vol. 33 Issue 9, p1582-1595.

Optimal Design for the Precise Estimation of an Interaction Threshold: The Impact of Exposure to a Mixture of 18 Polyhalogenated Aromatic Hydrocarbons.

Authors: Yeatts, Sharon D. Gennings, Chris Crofton, Kevin M.

Source: Risk Analysis: An International Journal. Oct2012, Vol. 32 Issue 10, p1784-1797.

Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches.

Authors: Noyes, Pamela D. Friedman, Katie Paul Browne, Patience et al.

Source: Environmental Health Perspectives. Sep2019, Vol. 127 Issue 9, p1-20. 20p. 3 Diagrams, 3 Charts.

Subject Terms: *Biomarkers, *Physiological control systems, *Environmental health, *Environmental monitoring, *Environmentally induced diseases, *Pollutants, *Toxicity testing, *Environmental exposure, *Environmental medicine, Thyroid gland physiology, Hypothalamic hormones, Medical technology, Thyroid diseases, Thyroid hormones, Thyrotropin, Signal peptides, In vitro studies, Standards

Company/Entity: Organisation for Economic Co-operation & Development

Author Index for Volume 33.

Source: Fundamental & Applied Toxicology. 1996, Vol. 33 Issue 2, p298-298. 1p.

Author Index for Volume 29.

Source: Fundamental & Applied Toxicology. 1996, Vol. 29 Issue 2, p302-302. 1p.

European Food Safety Authority database for in vivo developmental neurotoxicity studies of pesticides.

Authors: Mangas, Iris Spilioti, Eliana Terron, Andrea et al.

Source: Critical Reviews in Toxicology. May2025, Vol. 55 Issue 5, p587-598. 12p.

The Next Generation of Risk Assessment Multi-Year Study--Highlights of Findings, Applications to Risk Assessment, and Future Directions.

Authors: Cote, IIa Andersen, Melvin E. Ankley, Gerald T. et al.

Source: Environmental Health Perspectives. Nov2016, Vol. 124 Issue 11, p1671-1682. 12p. 1 Diagram, 2 Charts, 1 Graph.

Subject Terms: *Molecular biology, *Physiological effects of chemicals, *Toxic substance exposure, *Biomarkers, *Dose-response relationship in biochemistry, *Environmental health, *Hazardous substances, *Public health, *Toxicology, *Environmental exposure, Risk assessment, Biological research methodology, Computational biology, Systems biology, Bioinformatics, Genomics, Proteomics

Company/Entity: United States. Environmental Protection Agency

Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure.

Authors: Shah, Imran Setzer, R. Woodrow Jack, John et al.

Source: Environmental Health Perspectives. Jul2016, Vol. 124 Issue 7, p910-919. 10p. 5 Graphs.

Subject Terms: *Dimethyl sulfoxide, *Hazardous substances, *Organic compounds, *Pesticides, *Toxicity testing, Protein analysis, Cell analysis, Acids, Cell culture, Cell cycle, Confidence intervals, Digital diagnostic imaging, Paclitaxel, Stains & staining (Microscopy), Time, Phenotypes, Bioinformatics, Data analysis software, Descriptive statistics, Fluorescent dyes, In vitro studies

Current Perspectives on the Use of Alternative Species in Human Health and Ecological Hazard Assessments.

Authors: Perkins, Edward J. Ankley, Gerald T. Crofton, Kevin M. et al.

Source: Environmental Health Perspectives. Sep2013, Vol. 121 Issue 9, p1002-1010. 9p. 2 Diagrams, 3 Charts.

Subject Terms: *Animal experimentation, *Fishes, *Health, *Organic compounds, *Environmental exposure, Biological assay, Biological models, Pharmaceutical technology, Rats, Risk assessment, In vitro studies

Using in Vitro High Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals.

Authors: Rotroff, Daniel M. Dix, David J. Houck, Keith A. et al.

Source: Environmental Health Perspectives. Jan2013, Vol. 121 Issue 1, p7-14. 8p.

Subject Terms: *Organic compounds, *Pollutants, *Environmental exposure, Organic compound analysis, Confidence intervals, Estrogen antagonists, Hormone antagonists, Medical protocols, MEDLINE, Online information services, Systematic reviews, High throughput screening (Drug development), Endocrine system, Predictive tests, Descriptive statistics, In vitro studies, Meta-synthesis, In vivo studies

URL: 87008057

Supplemental Material. Using in Vitro High-Throughput Screening Assays to Identify Potential Endocrine Disrupting Chemicals.

Authors: Rotroff, Daniel M. Dix, David J. Houck, Keith A. et al.

Source: Environmental Health Perspectives. Jan2013, Vol. 121 Issue 1, p1-13. 13p. 3 Charts.

Subject Terms: *Animal experimentation, *Environmental exposure, High throughput screening (Drug development), Chemical laboratory equipment, Laboratory animals, World Wide Web, Endocrine system

Additivity of Pyrethroid Actions on Sodium Influx in Cerebrocortical Neurons in Primary Culture.

Authors: Zhengyu Cao Shafer, Timothy J. Crofton, Kevin M. et al.

Source: Environmental Health Perspectives. Sep2011, Vol. 119 Issue 9, p1239-1246. 8p. 2 Charts, 7 Graphs.

Evidence for Dose-Additive Effects of Pyrethroids on Motor Activity in Rats.

Authors: Wolansky, Marcelo J. Gennings, Chris DeVito, Michael J. et al.

Source: Environmental Health Perspectives. Oct2009, Vol. 117 Issue 10, p1563-1570. 8p. 5 Charts, 2 Graphs.

Subject Terms: *Pyrethroids, *Physiological effects of insecticides, *Dose-response relationship in biochemistry, *Solution (Chemistry), Motor ability, Neurotoxicology, Corn oil, Numerical analysis, Laboratory rats

Thyroid-Disrupting Chemicals: Interpreting Upstream Biomarkers of Adverse Outcomes.

Authors: Miller, Mark D. Crofton, Kevin M. Rice, Deborah C. et al.

Source: Environmental Health Perspectives. Jul2009, Vol. 117 Issue 7, p1033-1041. 9p. 3 Diagrams, 1 Chart, 2 Graphs.

A Retrospective Performance Assessment of the Developmental Neurotoxicity Study in Support of OECD Test Guideline 426.

Authors: Makris, Susan L. Raffaele, Kathleen Allen, Sandra et al.

Source: Environmental Health Perspectives. Jan2009, Vol. 117 Issue 1, p17-25. 9p. 4 Charts.

Subject Terms: Retrospective studies, Neurotoxicology, Children's health, Risk assessment, Adult education workshops

Geographic Terms: United States

Company/Entity: United States. Environmental Protection Agency