Search Results - "Datoo, Mehreen S"

The R21/Matrix-M malaria vaccine: questions remain – Author's reply.

Authors: Datoo, Mehreen S Hill, Adrian V S Beaumont, Emma et al.

Source: Lancet. Jan2025, Vol. 405 Issue 10475, p299-301. 3p.

Safety and efficacy of malaria vaccine candidate R21/Matrix-M in African children: a multicentre, double-blind, randomised, phase 3 trial.

Authors: Datoo, Mehreen S Dicko, Alassane Tinto, Halidou et al.

Source: Lancet. Feb2024, Vol. 403 Issue 10426, p533-544. 12p.

Safety and immunogenicity of varied doses of R21/Matrix-M™ vaccine at three years follow-up: A phase 1b age deescalation, dose-escalation trial in adults, children, and infants in Kilifi-Kenya.

Authors: Sang, Samuel Datoo, Mehreen S. Otieno, Edward et al.

Source: Wellcome Open Research. 2023, p1-16. 16p.

Subject Terms: *Health, *Vaccination, *Immunization, Immunogenetics, Infants, Children

Efficacy and immunogenicity of R21/Matrix-M vaccine against clinical malaria after 2 years' follow-up in children in Burkina Faso: a phase 1/2b randomised controlled trial.

Authors: Datoo, Mehreen S Natama, Hamtandi Magloire Somé, Athanase et al.

Source: Lancet Infectious Diseases. Dec2022, Vol. 22 Issue 12, p1728-1736. 9p.

Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial.

Authors: Datoo, Mehreen S Natama, Magloire H Somé, Athanase et al.

Source: Lancet. 5/15/2021, Vol. 397 Issue 10287, p1809-1818. 10p.

Subjects: Malaria vaccines, National Institute for Health Research (Great Britain), Wellcome Trust (London, England), Randomized controlled trials, Vaccine effectiveness, Vaccine safety, Rabies vaccines, Malaria prevention, Proteins, Evaluation research, Research funding, Immunoglobulins, Blind experiment, Statistical sampling, Treatment effectiveness, Viral antigens, Viral vaccines, Glycosides, Research, Research methodology, Vaccines, Comparative studies, Immunomodulators, Proportional hazards models, Nanoparticles

Geographic Terms: Burkina Faso

Developing a new anti-sporozoite malaria vaccine

Authors: Datoo, Mehreen S.

Committee Members: Hill, Adrian; Ewer, Katie

URL: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.879235

The public health impact and cost-effectiveness of the R21/Matrix-M malaria vaccine: a mathematical modelling study.

Authors: Schmit, Nora Topazian, Hillary M Natama, H Magloire et al.

Source: Lancet Infectious Diseases. May2024, Vol. 24 Issue 5, p465-475. 11p.

R21/Matrix-M malaria vaccine drives diverse immune responses in pre-exposed adults: insights from a phase IIb controlled human malaria infection trial.

Authors: Kibwana E Bundi C Kimani D et al.

Source: Frontiers in immunology [Front Immunol] 2025 Jul 07; Vol. 16, pp. 1620365. Date of Electronic Publication: 2025 Jul 07 (Print Publication: 2025).

Publication Type: Journal Article; Clinical Trial, Phase II

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Malaria vaccine protection against intradermal or venous parasites: a randomized phase 2b human challenge trial.

Authors: Kapulu MC Orenge F Kimani D et al.

Source: Nature medicine [Nat Med] 2026 Jan; Vol. 32 (1), pp. 178-185. Date of Electronic Publication: 2026 Jan 06.

Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II

Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

R21 in Matrix-M adjuvant in UK malaria-naive adult men and non-pregnant women aged 18-45 years: an open-label, partially blinded, phase 1-2a controlled human malaria infection study.

Authors: Venkatraman N Silman D Bellamy D et al.

Source: The Lancet. Microbe [Lancet Microbe] 2025 Mar; Vol. 6 (3), pp. 100867. Date of Electronic Publication: 2025 Jan 10.

Publication Type: Journal Article; Clinical Trial, Phase I; Clinical Trial, Phase II

Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101769019 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-5247 (Electronic) Linking ISSN: 26665247 NLM ISO Abbreviation: Lancet Microbe Subsets: MEDLINE

Evaluation of a novel malaria anti-sporozoite vaccine candidate, R21 in Matrix-M adjuvant, in the UK and Burkina Faso: two phase 1, first-in-human trials.

Authors: Venkatraman N Tiono AB Bowyer G et al.

Source: The Lancet. Microbe [Lancet Microbe] 2025 Mar; Vol. 6 (3), pp. 100868. Date of Electronic Publication: 2025 Jan 10.

Publication Type: Journal Article; Clinical Trial, Phase I; Randomized Controlled Trial

Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101769019 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-5247 (Electronic) Linking ISSN: 26665247 NLM ISO Abbreviation: Lancet Microbe Subsets: MEDLINE

Deep Immune Phenotyping and Single-Cell Transcriptomics Allow Identification of Circulating TRM-Like Cells Which Correlate With Liver-Stage Immunity and Vaccine-Induced Protection From Malaria.

Authors: Noé A Datoo MS Flaxman A et al.

Source: Frontiers in immunology [Front Immunol] 2022 Feb 07; Vol. 13, pp. 795463. Date of Electronic Publication: 2022 Feb 07 (Print Publication: 2022).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Safety and immunogenicity of varied doses of R21/Matrix-M™ vaccine at three years follow-up: A phase 1b age de-escalation, dose-escalation trial in adults, children, and infants in Kilifi-Kenya.

Authors: Sang S Datoo MS Otieno E et al.

Source: Wellcome open research [Wellcome Open Res] 2023 Oct 12; Vol. 8, pp. 450. Date of Electronic Publication: 2023 Oct 12 (Print Publication: 2023).

Publication Type: Journal Article

Journal Info: Publisher: Wellcome Trust Country of Publication: England NLM ID: 101696457 Publication Model: eCollection Cited Medium: Print ISSN: 2398-502X (Print) Linking ISSN: 2398502X NLM ISO Abbreviation: Wellcome Open Res Subsets: PubMed not MEDLINE

Mass administration of azithromycin reduces childhood mortality in Niger.

Authors: Murphy S Datoo MS

Source: Archives of disease in childhood. Education and practice edition [Arch Dis Child Educ Pract Ed] 2021 Oct; Vol. 106 (5), pp. 320. Date of Electronic Publication: 2020 Sep 08.

Publication Type: Journal Article; Comment

Journal Info: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101220684 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-0593 (Electronic) Linking ISSN: 17430585 NLM ISO Abbreviation: Arch Dis Child Educ Pract Ed Subsets: MEDLINE