Search Results - "Dienel GA"

Setting standards for brain collection procedures in metabolomic studies.

Authors: Dienel GA Nowak TS Jr

Source: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2026 Jun; Vol. 46 (6), pp. 1472-1479. Date of Electronic Publication: 2025 Jan 25.

Publication Type: Journal Article; Review

Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE

A Bird's-Eye View of Glycolytic Upregulation in Activated Brain: The Major Fate of Lactate Is Release From Activated Tissue, Not Shuttling to Nearby Neurons.

Authors: Dienel GA Rothman DL Mangia S

Source: Journal of neurochemistry [J Neurochem] 2025 Jun; Vol. 169 (6), pp. e70111.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

Revisiting phenylketonuria: Do high brain glycine levels caused by chronic hyperphenylalanemia contribute to brain dysfunction by modulating D-serine levels and NMDA receptor activity?

Authors: Dienel GA; Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Department of Cell Biology and Physiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA. Electronic address: gadienel@uams.edu.

Source: Analytical biochemistry [Anal Biochem] 2026 Jan; Vol. 708, pp. 115992. Date of Electronic Publication: 2025 Oct 14.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0370535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0309 (Electronic) Linking ISSN: 00032697 NLM ISO Abbreviation: Anal Biochem Subsets: MEDLINE

A tribute to Leif Hertz: The historical context of his pioneering studies of the roles of astrocytes in brain energy metabolism, neurotransmission, cognitive functions, and pharmacology identifies important, unresolved topics for future studies.

Authors: Dienel GA Schousboe A McKenna MC et al.

Source: Journal of neurochemistry [J Neurochem] 2024 May; Vol. 168 (5), pp. 461-495. Date of Electronic Publication: 2023 Apr 13.

Publication Type: Biography; Journal Article; Review; Research Support, N.I.H., Extramural

Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

In vivo calibration of genetically encoded metabolite biosensors must account for metabolite metabolism during calibration and cellular volume.

Authors: Dienel GA Rothman DL

Source: Journal of neurochemistry [J Neurochem] 2024 May; Vol. 168 (5), pp. 506-532. Date of Electronic Publication: 2023 Mar 27.

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural

Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, pCO2, and pO2.

Authors: DiNuzzo M Dienel GA Behar KL et al.

Source: Journal of neurochemistry [J Neurochem] 2024 May; Vol. 168 (5), pp. 632-662. Date of Electronic Publication: 2023 Jun 21.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

Mechanistic stoichiometric relationship between the rates of neurotransmission and neuronal glucose oxidation: Reevaluation of and alternatives to the pseudo-malate-aspartate shuttle model.

Authors: Rothman DL Behar KL Dienel GA

Source: Journal of neurochemistry [J Neurochem] 2024 May; Vol. 168 (5), pp. 555-591. Date of Electronic Publication: 2022 Sep 11.

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural

Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

Reply to Comment by Quistorff: ATP is not consumed solely by hydrolytic reactions.

Authors: Dienel GA Lauritzen M

Source: Fluids and barriers of the CNS [Fluids Barriers CNS] 2025 Oct 23; Vol. 22 (1), pp. 105. Date of Electronic Publication: 2025 Oct 23.

Publication Type: Comment; Letter

Journal Info: Publisher: Biomed Central Country of Publication: England NLM ID: 101553157 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-8118 (Electronic) Linking ISSN: 20458118 NLM ISO Abbreviation: Fluids Barriers CNS Subsets: MEDLINE

Comment on the Editorial "Embracing the Modern Biochemistry of Brain Metabolism".

Authors: Dienel GA Rothman DL Mangia S

Source: Journal of neurochemistry [J Neurochem] 2025 Aug; Vol. 169 (8), pp. e70197.

Publication Type: Letter

Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

A budget for brain metabolic water production by glucose catabolism during rest, rises in activity and sleep.

Authors: Dienel GA Lauritzen M

Source: Fluids and barriers of the CNS [Fluids Barriers CNS] 2025 May 06; Vol. 22 (1), pp. 44. Date of Electronic Publication: 2025 May 06.

Publication Type: Journal Article; Review

Journal Info: Publisher: Biomed Central Country of Publication: England NLM ID: 101553157 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-8118 (Electronic) Linking ISSN: 20458118 NLM ISO Abbreviation: Fluids Barriers CNS Subsets: MEDLINE

Reduced removal of waste products from energy metabolism takes center stage in human brain aging.

Authors: Mangia S DiNuzzo M Ponticorvo S et al.

Source: Scientific reports [Sci Rep] 2025 Mar 08; Vol. 15 (1), pp. 8127. Date of Electronic Publication: 2025 Mar 08.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Potential new roles for glycogen in epilepsy.

Authors: Dienel GA Gillinder L McGonigal A et al.

Source: Epilepsia [Epilepsia] 2023 Jan; Vol. 64 (1), pp. 29-53. Date of Electronic Publication: 2022 Nov 01.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE

Brain glycogen content is increased in the acute and interictal chronic stages of the mouse pilocarpine model of epilepsy.

Authors: Seo GY Neal ES Han F et al.

Source: Epilepsia open [Epilepsia Open] 2022 Jun; Vol. 7 (2), pp. 361-367. Date of Electronic Publication: 2022 Apr 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101692036 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9239 (Electronic) Linking ISSN: 24709239 NLM ISO Abbreviation: Epilepsia Open Subsets: MEDLINE

Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission.

Authors: Rothman DL Dienel GA Behar KL et al.

Source: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2022 May; Vol. 42 (5), pp. 844-860. Date of Electronic Publication: 2022 Jan 07.

Publication Type: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE

Correction to: Reevaluation of Astrocyte‑Neuron Energy Metabolism with Astrocyte Volume Fraction Correction: Impact on Cellular Glucose Oxidation Rates, Glutamate-Glutamine Cycle Energetics, Glycogen Levels and Utilization Rates vs. Exercising Muscle, and Na⁺/K⁺ Pumping Rates.

Authors: Dienel GA Rothman DL

Source: Neurochemical research [Neurochem Res] 2022 Mar; Vol. 47 (3), pp. 811-812.

Publication Type: Published Erratum

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Print Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE; PubMed not MEDLINE

Stop the rot. Enzyme inactivation at brain harvest prevents artifacts: A guide for preservation of the in vivo concentrations of brain constituents.

Authors: Dienel GA; Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Department of Cell Biology and Physiology, University of New Mexico School of Medicine, Albuquerque, NM, USA.

Source: Journal of neurochemistry [J Neurochem] 2021 Sep; Vol. 158 (5), pp. 1007-1031. Date of Electronic Publication: 2021 Feb 26.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

Metabolomic and Imaging Mass Spectrometric Assays of Labile Brain Metabolites: Critical Importance of Brain Harvest Procedures.

Authors: Dienel GA; Department of Neurology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Mail Slot 500, Little Rock, AR, 72205, USA. gadienel@uams.edu.; Department of Cell Biology and Physiology, University of New Mexico School of Medicine, Albuquerque, NM, 87131, USA. gadienel@uams.edu.

Source: Neurochemical research [Neurochem Res] 2020 Nov; Vol. 45 (11), pp. 2586-2606. Date of Electronic Publication: 2020 Sep 19.

Publication Type: Journal Article; Review

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE

Reevaluation of Astrocyte-Neuron Energy Metabolism with Astrocyte Volume Fraction Correction: Impact on Cellular Glucose Oxidation Rates, Glutamate-Glutamine Cycle Energetics, Glycogen Levels and Utilization Rates vs. Exercising Muscle, and Na⁺/K⁺ Pumping Rates.

Authors: Dienel GA Rothman DL

Source: Neurochemical research [Neurochem Res] 2020 Nov; Vol. 45 (11), pp. 2607-2630. Date of Electronic Publication: 2020 Sep 18.

Publication Type: Journal Article; Review

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE

Hypothesis: A Novel Neuroprotective Role for Glucose-6-phosphatase (G6PC3) in Brain-To Maintain Energy-Dependent Functions Including Cognitive Processes.

Authors: Dienel GA; Department of Neurology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Mail Slot 500, Little Rock, AR, 72205, USA. gadienel@uams.edu.; Department of Cell Biology and Physiology, University of New Mexico School of Medicine, Albuquerque, NM, 87131, USA. gadienel@uams.edu.

Source: Neurochemical research [Neurochem Res] 2020 Nov; Vol. 45 (11), pp. 2529-2552. Date of Electronic Publication: 2020 Aug 19.

Publication Type: Journal Article; Review

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE

A functional account of stimulation-based aerobic glycolysis and its role in interpreting BOLD signal intensity increases in neuroimaging experiments.

Authors: Theriault JE Shaffer C Dienel GA et al.

Source: Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2023 Oct; Vol. 153, pp. 105373. Date of Electronic Publication: 2023 Aug 25.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Pergamon Press Country of Publication: United States NLM ID: 7806090 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7528 (Electronic) Linking ISSN: 01497634 NLM ISO Abbreviation: Neurosci Biobehav Rev Subsets: MEDLINE