Search Results - "Frayling TM"

An interleukin-18 polymorphism is associated with reduced serum concentrations and better physical functioning in older people.

Authors: Frayling TM Rafiq S Murray A et al.

Source: Journals of Gerontology Series A: Biological Sciences & Medical Sciences. Jan2007, Vol. 62 Issue 1, p73-78. 6p.

URL: 25540128

Genetic regulation of birth weight and fasting glucose by a common polymorphism in the islet cell promoter of the glucokinase gene.

Authors: Weedon MN Frayling TM Shields B et al.

Source: Diabetes. Feb2005, Vol. 54 Issue 2, p576-581. 6p.

A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.

Authors: Frayling TM Lindgren CM Chevre JC et al.

Source: Diabetes. Mar2003, Vol. 52 Issue 3, p872-881. 10p.

URL: 9257139

Parent-offspring trios: a resource to facilitate the identification of type 2 diabetes genes.

Authors: Frayling TM Walker M McCarthy MI et al.

Source: Diabetes. Dec99, Vol. 48 Issue 12, p2475-2479. 5p.

Interleukin-18 polymorphism and physical functioning in older people: a replication study and meta-analysis.

Authors: Thomas K Rafiq S Frayling TM et al.

Source: Journals of Gerontology Series A: Biological Sciences & Medical Sciences. Nov2009, Vol. 64A Issue 11, p1177-1182. 6p.

URL: 53299266

The fat mass-- and obesity-associated locus and dietary intake in children.

Authors: Timpson NJ Emmett PM Frayling TM et al.

Source: American Journal of Clinical Nutrition. Oct2008, Vol. 88 Issue 4, p971-978. 8p.

Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies.

Authors: Barroso I Luan J Wheeler E et al.

Source: Diabetes. Nov2008, Vol. 57 Issue 11, p3161-3165. 5p.

URL: 35452243

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function.

Authors: Pascoe L Tura A Patel SK et al.

Source: Diabetes. Dec2007, Vol. 56 Issue 12, p3101-3104. 4p.

URL: 28135169

The transcription factor 7-like 2 (TCF7L2) gene is associated with Type 2 diabetes in UK community-based cases, but the risk allele frequency is reduced compared with UK cases selected for genetic studies.

Authors: De Silva NM Steele A Shields B et al.

Source: Diabetic Medicine. Oct2007, Vol. 24 Issue 10, p1067-1072. 6p.

URL: 26595996

Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes: association analyses in 9,518 subjects.

Authors: Owen KR Groves CJ Hanson RL et al.

Source: Diabetes. Mar2007, Vol. 56 Issue 3, p879-883. 5p.

URL: 24497703

Assessment of the Role of Common Genetic Variation in the Transient Neonatal Diabetes Mellitus (TNDM) Region in Type 2 Diabetes: A Comparative Genomic and Tagging Single Nucleotide Polymorphism Approach.

Authors: Gloyn AL Mackay DJ Weedon MN et al.

Source: Diabetes. Aug2006, Vol. 55 Issue 8, p2272-2276. 5p.

URL: 22151811

Examining the relationships between the Pro12Ala variant in PPARG and Type 2 diabetes-related traits in UK samples.

Authors: Zeggini E Parkinson JRC Halford S et al.

Source: Diabetic Medicine. Dec2005, Vol. 22 Issue 12, p1696-1700. 5p.

URL: 19009737

A large-scale association analysis of common variation of the HNF1alpha gene with type 2 diabetes in the U.K. Caucasian population.

Authors: Weedon MN Owen KR Shields B et al.

Source: Diabetes. Aug2005, Vol. 54 Issue 8, p2487-2491. 5p.

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes.

Authors: Gloyn AL Pearson ER Antcliff JF et al.

Source: New England Journal of Medicine. 4/29/2004, Vol. 350 Issue 18, p1838-1849. 12p.

Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable.

Authors: Lawlor DA Timpson NJ Harbord RM et al.

Source: PLoS Medicine. Mar2008, Vol. 5 Issue 3, pe33-e33. 1p.

Genetics identifies obesity as a shared risk factor for co-occurring multiple long-term conditions.

Authors: Mounier N Voller B Masoli JAH et al.

Corporate Authors: Mounier N Voller B Masoli JAH et al.

Source: Communications medicine [Commun Med (Lond)] 2026 Feb 04; Vol. 6 (1), pp. 67. Date of Electronic Publication: 2026 Feb 04.

Publication Type: Journal Article

Journal Info: Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918250414506676 Publication Model: Electronic Cited Medium: Internet ISSN: 2730-664X (Electronic) Linking ISSN: 2730664X NLM ISO Abbreviation: Commun Med (Lond) Subsets: PubMed not MEDLINE

Getting to GRIPS with MR-Egger: Modelling directional pleiotropy independently of allele coding.

Authors: Dudbridge F Voller B Woodward RM et al.

Source: PLoS genetics [PLoS Genet] 2025 Dec 30; Vol. 21 (12), pp. e1011967. Date of Electronic Publication: 2025 Dec 30 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

Genetic and epidemiological evidence linking respiratory and musculoskeletal diseases: shared risk factors and intervention windows.

Authors: Murrin O Voller B Woodward RM et al.

Source: Respiratory research [Respir Res] 2026 Jun 09. Date of Electronic Publication: 2026 Jun 09.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE

Whole-genome sequencing analysis of anthropometric traits in 672,976 individuals reveals convergence between rare and common genetic associations.

Authors: Hawkes G Wright HIW Beaumont RN et al.

Source: Nature communications [Nat Commun] 2026 Feb 06; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 06.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Trans-eQTLs reveal the architecture of human gene regulatory networks.

Authors: Warmerdam CAR Westra HJ van der Graaf A et al.

Corporate Authors: Warmerdam CAR Westra HJ van der Graaf A et al.

Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 Feb 05. Date of Electronic Publication: 2026 Feb 05.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE