Search Results - "Gumpper RH"

Chemistry/structural biology of psychedelic drugs and their receptor(s).

Authors: Gumpper RH Nichols DE

Source: British journal of pharmacology [Br J Pharmacol] 2026 Jul; Vol. 183 (14), pp. 3920-3934. Date of Electronic Publication: 2024 Oct 02.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Histone decrotonylation plays a distinct role in HIV latency.

Authors: Li X Li D Tang Y et al.

Source: Science advances [Sci Adv] 2026 Apr 10; Vol. 12 (15), pp. eaec0149. Date of Electronic Publication: 2026 Apr 10.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

Structural insights into coffee bitter taste perception by TAS2R43 receptor.

Authors: Kim Y Gumpper RH Zhuang Y et al.

Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2026 Apr; Vol. 33 (4), pp. 701-710. Date of Electronic Publication: 2026 Apr 20.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

Differential Effects of Sodium on Agonist-Induced Conformational Transitions and Signaling at μ and κ Opioid Receptors.

Authors: Kuijer MB Fulton CJ Albert TL et al.

Source: Biochemistry [Biochemistry] 2025 Dec 16; Vol. 64 (24), pp. 4746-4757. Date of Electronic Publication: 2025 Dec 03.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

The polypharmacology of psychedelics reveals multiple targets for potential therapeutics.

Authors: Jain MK Gumpper RH Slocum ST et al.

Source: Neuron [Neuron] 2025 Oct 01; Vol. 113 (19), pp. 3129-3142.e9. Date of Electronic Publication: 2025 Jul 18.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

Differential effects of sodium on agonist-induced conformational transitions and signaling at μ and κ opioid receptors.

Authors: Kuijer B Fulton CJ Albert TL et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Sep 02. Date of Electronic Publication: 2025 Sep 02.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

The structural diversity of psychedelic drug actions revealed.

Authors: Gumpper RH Jain MK Kim K et al.

Source: Nature communications [Nat Commun] 2025 Mar 19; Vol. 16 (1), pp. 2734. Date of Electronic Publication: 2025 Mar 19.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Molecular Glues: A New Approach to Modulating GPCR Signaling Bias.

Authors: Kushnir J Gumpper RH

Source: Biochemistry [Biochemistry] 2025 Feb 18; Vol. 64 (4), pp. 749-759. Date of Electronic Publication: 2025 Feb 03.

Publication Type: Journal Article; Review; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

Structure-guided design of a peripherally restricted chemogenetic system.

Authors: Kang HJ Krumm BE Tassou A et al.

Source: Cell [Cell] 2024 Dec 26; Vol. 187 (26), pp. 7433-7449.e20. Date of Electronic Publication: 2024 Dec 03.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

High-affinity agonists reveal recognition motifs for the MRGPRD GPCR.

Authors: Wang C Liu Y Lanier M et al.

Source: Cell reports [Cell Rep] 2024 Dec 24; Vol. 43 (12), pp. 114942. Date of Electronic Publication: 2024 Nov 23.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

Author Correction: Bitter taste receptor activation by cholesterol and an intracellular tastant.

Authors: Kim Y Gumpper RH Liu Y et al.

Source: Nature [Nature] 2024 Jun; Vol. 630 (8016), pp. E5.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE; PubMed not MEDLINE

Bitter taste receptor activation by cholesterol and an intracellular tastant.

Authors: Kim Y Gumpper RH Liu Y et al.

Source: Nature [Nature] 2024 Apr; Vol. 628 (8008), pp. 664-671. Date of Electronic Publication: 2024 Apr 10.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Psychedelics: preclinical insights provide directions for future research.

Authors: Gumpper RH Roth BL

Source: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2024 Jan; Vol. 49 (1), pp. 119-127. Date of Electronic Publication: 2023 Mar 17.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE

DNA selection by the master transcription factor PU.1.

Authors: Terrell JR Taylor SJ Schneider AL et al.

Source: Cell reports [Cell Rep] 2023 Jul 25; Vol. 42 (7), pp. 112671. Date of Electronic Publication: 2023 Jun 22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

Psychedelics as Transformative Therapeutics.

Authors: Roth BL Gumpper RH

Source: The American journal of psychiatry [Am J Psychiatry] 2023 May 01; Vol. 180 (5), pp. 340-347.

Publication Type: Journal Article; Review; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Psychiatric Association Country of Publication: United States NLM ID: 0370512 Publication Model: Print Cited Medium: Internet ISSN: 1535-7228 (Electronic) Linking ISSN: 0002953X NLM ISO Abbreviation: Am J Psychiatry Subsets: MEDLINE

Ligand recognition and allosteric modulation of the human MRGPRX1 receptor.

Authors: Liu Y Cao C Huang XP et al.

Source: Nature chemical biology [Nat Chem Biol] 2023 Apr; Vol. 19 (4), pp. 416-422. Date of Electronic Publication: 2022 Oct 27.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

SnapShot: Psychedelics and serotonin receptor signaling.

Authors: Gumpper RH Roth BL

Source: Cell [Cell] 2023 Jan 05; Vol. 186 (1), pp. 232-232.e1.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Molecular basis for selective activation of DREADD-based chemogenetics.

Authors: Zhang S Gumpper RH Huang XP et al.

Source: Nature [Nature] 2022 Dec; Vol. 612 (7939), pp. 354-362. Date of Electronic Publication: 2022 Nov 30.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.

Authors: Cao C Barros-Álvarez X Zhang S et al.

Source: Neuron [Neuron] 2022 Oct 05; Vol. 110 (19), pp. 3154-3167.e7. Date of Electronic Publication: 2022 Sep 09.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

Molecular insights into the regulation of constitutive activity by RNA editing of 5HT2C serotonin receptors.

Authors: Gumpper RH Fay JF Roth BL

Source: Cell reports [Cell Rep] 2022 Aug 16; Vol. 40 (7), pp. 111211.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE