Search Results - "He, Yingfang"

Development of a novel molecular probe for visualizing mesothelin on the tumor via positron emission tomography.

Authors: He, Yingfang Kong, Jinping Wang, Ze et al.

Source: European Journal of Nuclear Medicine & Molecular Imaging. Jun2025, Vol. 52 Issue 7, p2605-2616. 12p.

Exploration of (R)-[¹¹C]YH168 as a PET tracer for imaging monoacylglycerol lipase in the brain: from mice to non-human primates.

Authors: He, Yingfang Zheng, MingQiang Gu, Jiwei et al.

Source: European Journal of Nuclear Medicine & Molecular Imaging. Mar2025, Vol. 52 Issue 4, p1556-1565. 10p.

Preclinical evaluation and pilot clinical study of [⁶⁸Ga]Ga-NOTA-H006 for non-invasive PET imaging of 5T4 oncofetal antigen.

Authors: He, Yingfang Tian, Ruhua Xu, Dong et al.

Source: European Journal of Nuclear Medicine & Molecular Imaging. Jan2025, Vol. 52 Issue 2, p611-622. 12p.

Metabotropic glutamate receptor 5 (mGluR5) is associated with neurodegeneration and amyloid deposition in Alzheimer's disease: A [¹⁸F]PSS232 PET/MRI study.

Authors: Wang, Jie He, Yingfang Chen, Xing et al.

Source: Alzheimer's Research & Therapy. 1/12/2024, Vol. 16 Issue 1, p1-13. 13p.

Proof-of-concept optimization of a copper-mediated ¹⁸F-radiosynthesis of a novel MAGL PET tracer on a high-throughput microdroplet platform and its macroscale translation.

Authors: Lu, Yingqing He, Yingfang Schibli, Roger et al.

Source: Lab on a Chip. 11/7/2023, Vol. 23 Issue 21, p4652-4663. 12p.

Subjects: Radiochemical purification, Positron emission tomography, Proof of concept, Radioactive tracers, Lipases

Recent progress in allosteric modulators for GluN2A subunit and development of GluN2A‐selective nuclear imaging probes.

Authors: He, Yingfang Mu, Linjing Ametamey, Simon M. et al.

Source: Journal of Labelled Compounds & Radiopharmaceuticals. 6/30/2019, Vol. 62 Issue 8, p552-560. 9p.

Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold.

Authors: He, Yingfang Gobbi, Luca C. Herde, Adrienne Müller et al.

Source: Nuclear Medicine & Biology. May2022, Vol. 108, p24-32. 9p.

P-298 - Rapid copper-mediated radiosynthesis optimization for a novel monoacylglycerol lipase PET tracer on a high-throughput microdroplet radiochemistry platform.

Authors: Lu, Yingqing He, Yingfang Schibli, Roger et al.

Source: Nuclear Medicine & Biology. Nov2023 Supplement, Vol. 126/127, pN.PAG-N.PAG. 1p.

P-074 - Identification of (R)-[18F]YH134 as a promising reversible MAGL PET tracer and the impact of peripheral MAGL blockade on its brain uptake.

Authors: Mu, Linjing He, Yingfang Krämer, Stefanie et al.

Source: Nuclear Medicine & Biology. Nov2023 Supplement, Vol. 126/127, pN.PAG-N.PAG. 1p.

O-04 - Development of a novel reversible monoacylglycerol lipase PET tracer bearing a morpholine-3-one scaffold.

Authors: He, Yingfang Grether, Uwe Taddio, Marco et al.

Source: Nuclear Medicine & Biology. 2022 Supplement, Vol. 108, pS5-S6. 2p.

Anti-HER2 nanobody 5F7-based theranostics using [68Ga]Ga-NOTA-5F7 PET/CT and [131I]SGMIB-5F7 SPECT/CT in HER2-positive breast cancer.

Authors: Wu, Yanfei Kong, Jingping Chen, Jixuan et al.

Source: European Journal of Nuclear Medicine & Molecular Imaging. Apr2026, p1-11. 11p.

Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain.

Authors: He, Yingfang Grether, Uwe Taddio, Marco F. et al.

Source: European Journal of Medicinal Chemistry. Dec2022, Vol. 243, pN.PAG-N.PAG. 1p.

Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2.

Authors: Wang, Jinling Beyer, Darja Vaccarin, Christian et al.

Source: European Journal of Nuclear Medicine & Molecular Imaging. Dec2024, Vol. 52 Issue 1, p9-21. 13p.

SP-005 - Development of reversible monoacylglycerol lipase PET tracers with improved brain uptake.

Authors: He, Yingfang Schild, Matthias Grether, Uwe et al.

Source: Nuclear Medicine & Biology. 2021:Supplement, Vol. 96, pS36-S36. 1p.

Development of PET radioligands for imaging monoacylglycerol lipase and N-methyl D-aspartate receptor subtype 2A in the brain

Authors: He, Yingfang

Committee Members: Supervisor; Schibli, Roger; Supervisor; Mu, Linjing; id_orcid 0000-0001-5354-1546; Supervisor; Gobbi, Luca; Supervisor; Krämer, Stefanie-Dorothea; id_orcid 0000-0002-0426-4340

URL: http://dx.doi.org/10.3929/ethz-b-000535148

Synthesis and evaluation of new 1-oxa-8-azaspiro[4.5]decane derivatives as candidate radioligands for sigma-1 receptors.

Authors: Tian, Jiale He, Yingfang Deuther-Conrad, Winnie et al.

Source: Bioorganic & Medicinal Chemistry. Jul2020, Vol. 28 Issue 14, pN.PAG-N.PAG. 1p.

Synthesis and biological evaluation of ⁶⁸Ga-labeled Pteroyl-Lys conjugates for folate receptor-targeted tumor imaging.

Authors: Zhang, Xuran Yu, Qian He, Yingfang et al.

Source: Journal of Labelled Compounds & Radiopharmaceuticals. Jul2016, Vol. 59 Issue 9, p346-353. 8p.

18F-Labeled indole-based analogs as highly selective radioligands for imaging sigma-2 receptors in the brain.

Authors: Wang, Liang Ye, Jiajun He, Yingfang et al.

Source: Bioorganic & Medicinal Chemistry. Jul2017, Vol. 25 Issue 14, p3792-3802. 11p.

Development of radiolabeling 2-oxo-2-(4-phenylpiperazin-1-yl)acetamide derivatives as potential molecular probes for excitatory amino acid transporter 2.

Authors: Song, Pengfei Gong, Kehao Xing, Liyuan et al.

Source: European Journal of Medicinal Chemistry. Nov2025, Vol. 298, pN.PAG-N.PAG. 1p.

O-67 - Quantitative Evaluation of a Novel PET Radioligand for the Monoacylglycerol Lipase (MAGL) in Non-Human Primates.

Authors: Gu, Jiwei Huang, Henry Carson, Richard et al.

Source: Nuclear Medicine & Biology. Nov2023 Supplement, Vol. 126/127, pN.PAG-N.PAG. 1p.