Search Results - "Hinck AP"

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell-Type-Specific TGFβ Modulators.

Authors: van Dinther M Schwartze T Zhang J et al.

Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Apr 20, pp. e75322. Date of Electronic Publication: 2026 Apr 20.

Publication Type: Journal Article

Journal Info: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

Molecular Engineering of the Helminth TGF-β Mimetics, TGM1 and TGM4, Reveals a Novel Antagonist of TGF-β Signaling in Fibroblasts.

Authors: Cunningham KT Ciancia C Campion T et al.

Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2026 Apr 15; Vol. 40 (7), pp. e71338.

Publication Type: Journal Article

Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

Decoding the Mechanism of Action of a Parasite TGFβ antagonist Inspires the Creation of Cell-type-specific TGFβ Modulators.

Authors: van Dinther M Schwartze T Zhang J et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 18. Date of Electronic Publication: 2026 Feb 18.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Structural and functional analysis of the TGF-β mimic, TGM-2: an immunomodulatory helminth protein.

Authors: Ntang EY Cunningham KT Singh SP et al.

Source: Genes and immunity [Genes Immun] 2026 Feb; Vol. 27 (1), pp. 117-129. Date of Electronic Publication: 2025 Dec 18.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100953417 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5470 (Electronic) Linking ISSN: 14664879 NLM ISO Abbreviation: Genes Immun Subsets: MEDLINE

Cytokines from parasites: manipulating host responses by molecular mimicry.

Authors: Maizels RM McSorley HJ Smits HH et al.

Source: The Biochemical journal [Biochem J] 2025 Apr 29; Vol. 482 (9). Date of Electronic Publication: 2025 Apr 29.

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Electronic Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

Design of high-affinity binders to immune modulating receptors for cancer immunotherapy.

Authors: Yang W Hicks DR Ghosh A et al.

Source: Nature communications [Nat Commun] 2025 Feb 26; Vol. 16 (1), pp. 2001. Date of Electronic Publication: 2025 Feb 26.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling.

Authors: Wieteska Ł Taylor AB Punch E et al.

Source: Nature communications [Nat Commun] 2025 Feb 26; Vol. 16 (1), pp. 1778. Date of Electronic Publication: 2025 Feb 26.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding.

Authors: Singh SP Smyth DJ Cunningham KT et al.

Source: EMBO reports [EMBO Rep] 2025 Jan; Vol. 26 (1), pp. 218-244. Date of Electronic Publication: 2024 Nov 28.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

Improved protein binder design using β-pairing targeted RFdiffusion.

Authors: Sappington I Toul M Lee DS et al.

Source: Nature communications [Nat Commun] 2026 Jan 10; Vol. 17 (1), pp. 1101. Date of Electronic Publication: 2026 Jan 10.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma.

Authors: Daley JD Mukherjee E Ferraro D et al.

Source: Cancer research communications [Cancer Res Commun] 2025 Aug 01; Vol. 5 (8), pp. 1441-1457. Date of Electronic Publication: 2025 Aug 08.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE

Th1 differentiation and function are inhibited in neonates following human metapneumovirus infection.

Authors: Brown E Lan J Parks OB et al.

Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2025 Jul 01; Vol. 214 (7), pp. 1827-1838.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

TGM6 is a helminth secretory product that mimics TGF-β binding to TGFBR2 to antagonize signaling in fibroblasts.

Authors: White SE Schwartze TA Mukundan A et al.

Source: Nature communications [Nat Commun] 2025 Feb 21; Vol. 16 (1), pp. 1847. Date of Electronic Publication: 2025 Feb 21.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Molecular Basis of Interchain Disulfide Bond Formation in BMP-9 and BMP-10.

Authors: Schwartze TA Morosky SA Rosato TL et al.

Source: Journal of molecular biology [J Mol Biol] 2025 Feb 15; Vol. 437 (4), pp. 168935. Date of Electronic Publication: 2025 Jan 08.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE

Ficolin-3 induces apoptosis and suppresses malignant property of hepatocellular carcinoma cells via the complement pathway.

Authors: Zheng G Wu L Bouamar H et al.

Source: Life sciences [Life Sci] 2024 Nov 15; Vol. 357, pp. 123103. Date of Electronic Publication: 2024 Sep 30.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE

Molecular basis of interchain disulfide-bond formation in BMP-9 and BMP-10.

Authors: Schwartze TA Morosky SA Rosato TL et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 17. Date of Electronic Publication: 2024 Oct 17.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Structures of TGF-β with betaglycan and the signaling receptors reveal the mechanism whereby betaglycan potentiates receptor complex assembly and signaling.

Authors: Wieteska Ł Taylor AB Punch E et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 22. Date of Electronic Publication: 2024 Jul 22.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Immunocompetent murine model of Ewing sarcoma reveals role for TGFβ inhibition to enhance immune infiltrates in Ewing tumors during radiation.

Authors: Daley JD Mukherjee E Tufino AC et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 10. Date of Electronic Publication: 2024 May 10.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Design of High Affinity Binders to Convex Protein Target Sites.

Authors: Yang W Hicks DR Ghosh A et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 02. Date of Electronic Publication: 2024 May 02.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Betaglycan sustains HGF/Met signaling in lung cancer and endothelial cells promoting cell migration and tumor growth.

Authors: Cervantes-Villagrana RD Mendoza V Hinck CS et al.

Source: Heliyon [Heliyon] 2024 Apr 30; Vol. 10 (9), pp. e30520. Date of Electronic Publication: 2024 Apr 30 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101672560 Publication Model: eCollection Cited Medium: Print ISSN: 2405-8440 (Print) Linking ISSN: 24058440 NLM ISO Abbreviation: Heliyon Subsets: PubMed not MEDLINE

Shear Stress and Sub-Femtomolar Levels of Ligand Synergize to Activate ALK1 Signaling in Endothelial Cells.

Authors: Cheng YW Anzell AR Morosky SA et al.

Source: Cells [Cells] 2024 Feb 05; Vol. 13 (3). Date of Electronic Publication: 2024 Feb 05.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE