Search Results - "Holtzman DM"

Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β.

Authors: Koffie RM Hashimoto T Tai HC et al.

Source: Brain: A Journal of Neurology; Jul2012, Vol. 135 Issue 7, p2155-2168, 14p

Relationship of dementia screening tests with biomarkers of Alzheimer's disease.

Authors: Galvin JE Fagan AM Holtzman DM et al.

Source: Brain: A Journal of Neurology; Nov2010, Vol. 133 Issue 11, p3290-3300, 11p

Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls.

Authors: Esparza TJ Zhao H Cirrito JR et al.

Source: Annals of Neurology. Jan2013, Vol. 73 Issue 1, p104-119. 16p.

Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer's disease.

Authors: Portelius E Zetterberg H Dean RA et al.

Source: Journal of Alzheimer's Disease. 2012, Vol. 28 Issue 1, p335-341. 7p.

Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction.

Authors: Hata S Fujishige S Araki Y et al.

Source: Annals of Neurology. Jun2011, Vol. 69 Issue 6, p1026-1031. 6p.

Caffeine suppresses amyloid-beta levels in plasma and brain of Alzheimer's disease transgenic mice.

Authors: Cao C Cirrito JR Lin X et al.

Source: Journal of Alzheimer's Disease. 2009, Vol. 17 Issue 3, p681-697. 17p.

A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system.

Authors: Bateman RJ Siemers ER Mawuenyega KG et al.

Source: Annals of Neurology. Jul2009, Vol. 66 Issue 1, p48-54. 7p.

Decreased cerebrospinal fluid Abeta(42) correlates with brain atrophy in cognitively normal elderly.

Authors: Fagan AM Head D Shah AR et al.

Source: Annals of Neurology. Feb2009, Vol. 65 Issue 2, p176-183. 8p.

Extreme cerebrospinal fluid amyloid beta levels identify family with late-onset Alzheimer's disease presenilin 1 mutation.

Authors: Kauwe JS Jacquart S Chakraverty S et al.

Source: Annals of Neurology. May2007, Vol. 61 Issue 5, p446-453. 8p.

Blood-based proteomic signature of amyloidosis: identification of novel regulators of amyloid load.

Authors: Chen Y Duggan MR Timsina J et al.

Corporate Authors: Chen Y Duggan MR Timsina J et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Jun; Vol. 22 (6), pp. e71611.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

GPND-AI NULISA: A 15-Protein AI classifier for diagnosis and co-pathology profiling across neurodegenerative diseases.

Authors: Xu Y Denkinger MN Liu M et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 May; Vol. 22 (5), pp. e71420.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

Low overlap of plasma and CSF protein quantitative trait loci affects protein discovery for neurological disease.

Authors: Western D Yang C Timsina J et al.

Source: Science translational medicine [Sci Transl Med] 2026 Apr 29; Vol. 18 (847), pp. eadz2016. Date of Electronic Publication: 2026 Apr 29.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Targeting amyloid-β pathology by chimeric antigen receptor astrocyte (CAR-A) therapy.

Authors: Chen Y Liu Y Nguyen K et al.

Source: Science (New York, N.Y.) [Science] 2026 Mar 05; Vol. 391 (6789), pp. eads3972. Date of Electronic Publication: 2026 Mar 05.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Analyses of plasma multi-omic data across ancestries identify novel pathways implicated in Alzheimer's disease.

Authors: Yang C Timsina J Liu M et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Feb; Vol. 22 (2), pp. e71164.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

Variability of longitudinal sleep monitoring in amyloid-negative and amyloid-positive cognitively unimpaired and mildly impaired older adults.

Authors: Pedersen TJ Lu R Toedebusch C et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Oct; Vol. 21 (10), pp. e70761.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

Early binding of anti-amyloid antibodies to CAA drives complement activation, inflammation and ARIA in mice.

Authors: Bathini P Schilling S Rahfeld JU et al.

Source: Molecular neurodegeneration [Mol Neurodegener] 2026 Jun 26. Date of Electronic Publication: 2026 Jun 26.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE

Longitudinal multiphoton imaging of cerebral amyloid angiopathy in response to anti-ApoE4 immunotherapy in mice.

Authors: Bonnar O Saadi F Sanchez-Mico MV et al.

Source: Molecular neurodegeneration [Mol Neurodegener] 2026 Jun 11. Date of Electronic Publication: 2026 Jun 11.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE

Identification of genetic modifiers of autosomal dominant Alzheimer's disease: a genome-wide association study.

Authors: Patel M Feng W Mckay NS et al.

Corporate Authors: Patel M Feng W Mckay NS et al.

Source: The Lancet. Neurology [Lancet Neurol] 2026 Jun; Vol. 25 (6), pp. 581-590.

Publication Type: Journal Article

Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 101139309 Publication Model: Print Cited Medium: Internet ISSN: 1474-4465 (Electronic) Linking ISSN: 14744422 NLM ISO Abbreviation: Lancet Neurol Subsets: MEDLINE

Neuroproteasomes regulate endogenous tau paired helical filament formation in an APOE genotype- and age-dependent manner.

Authors: Paradise V Konrad-Vicario KD Nguyen C et al.

Source: Nature neuroscience [Nat Neurosci] 2026 May 29. Date of Electronic Publication: 2026 May 29.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE

Early syndecan-4 upregulation predicts cognitive and pathological trajectories in Alzheimer disease.

Authors: Tarawneh R Moulder KL Topouza DG et al.

Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2026 May 07; Vol. 18 (1). Date of Electronic Publication: 2026 May 07.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE