Search Results - "Iavarone L"

Safety and pharmacokinetics of GSK3494245, a highly selective Leishmaniasis kinetoplastid proteasome inhibitor for the treatment of visceral leishmaniasis: A Phase 1, randomized, single ascending dose escalation study in healthy participants.

Authors: Moodley M Kostapanos M Iavarone L et al.

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2026 May 13; Vol. 20 (5), pp. e0014181. Date of Electronic Publication: 2026 May 13 (Print Publication: 2026).

Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

Clinical activity and safety of nivolumab in combination with ipilimumab in metastatic melanoma: findings from REALIPINIVO, a real-world study.

Authors: Caraglia F Argenziano G Scala M et al.

Source: Frontiers in immunology [Front Immunol] 2026 Apr 16; Vol. 17, pp. 1738772. Date of Electronic Publication: 2026 Apr 16 (Print Publication: 2026).

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Molecular pharmacology and structural insights of naloxone: a comprehensive review.

Authors: Reddyrajula, Rajkumar Veeramachaneni, Yeshaswini Gadiraju, Vaishnavi et al.

Source: Discover Molecules (3004-9350). 6/21/2026, Vol. 3 Issue 1, p1-25. 25p.

Mapping the Extended Pain Pathway: Human Genetic and Multi-Omic Strategies for Next-Generation Analgesics.

Authors: Koivisto, Ari-Pekka¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Apr2026, Vol. 27 Issue 7, p3035. 17p.

Targeting Na v Channels for Pain Relief: Structural Insights and Therapeutic Opportunities.

Authors: Xie, Yuzhen Huang, Xiaoshuang Lu, Fangzhou et al.

Source: International Journal of Molecular Sciences. Feb2026, Vol. 27 Issue 3, p1180. 23p.

Validity and Reliability of the Turkish Version of the Environmental Health Literacy Scale.

Authors: Akgül Gündoğdu, Nurcan Selçuk Tosun, Alime Dağcı Günal, Büşra

Source: Journal of Evaluation in Clinical Practice. Feb2025, Vol. 31 Issue 1, p1-10. 10p.

Bioremediation of Chlorate and Chromium Contamination with Native Microbial Culture in Cold Climate.

Authors: Motevasselin, Mehdi Gorczyca, Beata Kalinovich, Indra et al.

Source: Ground Water Monitoring & Remediation; Jan2024, Vol. 44 Issue 1, p46-56, 11p

ST‐2560, a selective inhibitor of the NaV1.7 sodium channel, affects nocifensive and cardiovascular reflexes in non‐human primates.

Authors: Mulcahy, John V. Beckley, Jacob T. Klas, Sheri D. et al.

Source: British Journal of Pharmacology. Sep2024, Vol. 181 Issue 17, p3160-3171. 12p.

Linker minimization and characterization of Fc-fused interleukin-17A for increased in vivo half-life.

Authors: Wu, Qiu C Lee, Jungmin Swaminathan, Aishwarya et al.

Source: PEDS: Protein Engineering, Design & Selection. 2025, Vol. 38, p1-11. 11p.

Subjects: Interleukin-17, Pharmacokinetics, Protein engineering, Cytokines, Chimeric proteins, Inflammation, Regeneration (Biology)

Clinical Phenotypes of Diabetic Peripheral Neuropathy: Implications for Phenotypic-Based Therapeutics Strategies.

Authors: Jie-Eun Lee Jong Chul Won

Source: Diabetes & Metabolism Journal. Jul2025, Vol. 49 Issue 4, p542-564. 23p.

Exposure to Secondhand Smoke Extract Increases Cisplatin Resistance in Head and Neck Cancer Cells.

Authors: Sadhasivam, Balaji Manyanga, Jimmy Ganapathy, Vengatesh et al.

Source: International Journal of Molecular Sciences. Jan2024, Vol. 25 Issue 2, p1032. 18p.

Detrimental Effect of T261I and R287W SMAD3 Variants on Early Osteoarthritis: A Potential Anti‐Inflammatory Molecule for Personalized Treatment.

Authors: V, Janakiraman M, Sudhan Ahmad, Sheikh F. et al.

Source: Advanced Theory & Simulations. Apr2025, Vol. 8 Issue 4, p1-14. 14p.

Preclinical Animal Models to Investigate the Role of Na v 1.7 Ion Channels in Pain.

Authors: Yogi, Alvaro Banderali, Umberto Moreno, Maria J. et al.

Source: Life (2075-1729). Apr2025, Vol. 15 Issue 4, p640. 30p.

Ascending single-dose study of the safety, pharmacokinetics, and pharmacodynamics of CSTI-500, a novel monoamine triple reuptake inhibitor, first-in-human.

Authors: Appel L Risinger R Wall A et al.

Source: Psychopharmacology [Psychopharmacology (Berl)] 2026 Mar; Vol. 243 (3), pp. 565-580. Date of Electronic Publication: 2025 Aug 11.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE

Spanlastic Nano-Vesicles: A Novel Approach to Improve the Dissolution, Bioavailability, and Pharmacokinetic Behavior of Famotidine.

Authors: Almohamady, Hend I. Mortagi, Yasmin Gad, Shadeed et al.

Source: Pharmaceuticals (14248247). Dec2024, Vol. 17 Issue 12, p1614. 25p.

Design and Synthesis of Potential Multi-Target Antidepressants: Exploration of 1-(4-(7-Azaindole)-3,6-dihydropyridin-1-yl)alkyl-3-(1 H -indol-3-yl)pyrrolidine-2,5-dione Derivatives with Affinity for the Serotonin Transporter.

Authors: Wróbel, Martyna Z. Chodkowski, Andrzej Siwek, Agata et al.

Source: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 20, p11276. 18p.

Novel drugs affecting diabetic peripheral neuropathy.

Authors: Saleh, Dalia O. Sedik, Ahmed A.

Source: Iranian Journal of Basic Medical Sciences. Jun2024, Vol. 27 Issue 6, p657-670. 14p.

Design and Synthesis of D 3 R Bitopic Ligands with Flexible Secondary Binding Fragments: Radioligand Binding and Computational Chemistry Studies.

Authors: Tian, Gui-Long Hsieh, Chia-Ju Taylor, Michelle et al.

Source: Molecules. Jan2024, Vol. 29 Issue 1, p123. 13p.

Development of long-acting local anesthetics: a long way from basic research to clinical application.

Authors: Oda, Yutaka¹ (AUTHOR) yutakaodayutaka@gmail.com

Source: Journal of Anesthesia. Oct2024, Vol. 38 Issue 5, p581-583. 3p.

Resveratrol alleviates diabetic mechanical allodynia in rats by downregulating P2X3R.

Authors: Cui, Yuanyuan Li, Yuting Ning, Jiayi et al.

Source: Molecular Medicine Reports. Aug2020, Vol. 22 Issue 2, p957-963. 7p.