Search Results - "Kearns FL"

D614G reshapes allosteric networks and opening mechanisms of SARS-CoV-2 spikes.

Authors: Kearns FL Bogetti AT Calvó-Tusell C et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 May 12; Vol. 123 (19), pp. e2504793123. Date of Electronic Publication: 2026 May 08.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Condensate-Like Organization in Respiratory Aerosols Modulates the Dynamics of an Airborne Virus.

Authors: Wauer NA Calvó-Tusell C Dommer AC et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 04. Date of Electronic Publication: 2026 May 04.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Structural dynamics and allosteric communication of a SARS-like bat coronavirus spike glycoprotein.

Authors: Balogun TA Kearns FL Calvó-Tusell C et al.

Source: Biophysical journal [Biophys J] 2026 Apr 22. Date of Electronic Publication: 2026 Apr 22.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

Allosteric modulation by the fatty acid site in the glycosylated SARS-CoV-2 spike.

Authors: Oliveira ASF Kearns FL Rosenfeld MA et al.

Source: ELife [Elife] 2025 Apr 10; Vol. 13. Date of Electronic Publication: 2025 Apr 10.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Distinct pathways for evolution of enhanced receptor binding and cell entry in SARS-like bat coronaviruses.

Authors: Tse AL Acreman CM Ricardo-Lax I et al.

Source: PLoS pathogens [PLoS Pathog] 2024 Nov 15; Vol. 20 (11), pp. e1012704. Date of Electronic Publication: 2024 Nov 15 (Print Publication: 2024).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Simulation-driven design of stabilized SARS-CoV-2 spike S2 immunogens.

Authors: Nuqui X Casalino L Zhou L et al.

Source: Nature communications [Nat Commun] 2024 Aug 27; Vol. 15 (1), pp. 7370. Date of Electronic Publication: 2024 Aug 27.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

An unconventional HxD motif orchestrates coatomer-dependent coronavirus morphogenesis.

Authors: Mohona S Shakya AK Singh S et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 17. Date of Electronic Publication: 2025 Oct 17.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.

Authors: Chongsaritsinsuk J Steigmeyer AD Mahoney KE et al.

Source: Nature communications [Nat Commun] 2023 Oct 04; Vol. 14 (1), pp. 6169. Date of Electronic Publication: 2023 Oct 04.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

SARS CoV-2 spike adopts distinct conformational ensembles in situ.

Authors: Gramm AJ Braet SM Srinivasu BY et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Mar 05. Date of Electronic Publication: 2025 Mar 05.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Mining for Potent Inhibitors through Artificial Intelligence and Physics: A Unified Methodology for Ligand Based and Structure Based Drug Design.

Authors: Li J Zhang O Sun K et al.

Source: Journal of chemical information and modeling [J Chem Inf Model] 2024 Dec 23; Vol. 64 (24), pp. 9082-9097. Date of Electronic Publication: 2024 Jun 06.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

Breaking Down the Bottlebrush: Atomically Detailed Structural Dynamics of Mucins.

Authors: Kearns FL Rosenfeld MA Amaro RE

Source: Journal of chemical information and modeling [J Chem Inf Model] 2024 Oct 28; Vol. 64 (20), pp. 7949-7965. Date of Electronic Publication: 2024 Sep 27.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

CHARMM at 45: Enhancements in Accessibility, Functionality, and Speed.

Authors: Hwang W Austin SL Blondel A et al.

Source: The journal of physical chemistry. B [J Phys Chem B] 2024 Oct 17; Vol. 128 (41), pp. 9976-10042. Date of Electronic Publication: 2024 Sep 20.

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Intramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5207 (Electronic) Linking ISSN: 15205207 NLM ISO Abbreviation: J Phys Chem B Subsets: MEDLINE

Distinct pathway for evolution of enhanced receptor binding and cell entry in SARS-like bat coronaviruses.

Authors: Tse AL Acreman CM Ricardo-Lax I et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 13. Date of Electronic Publication: 2024 Jul 13.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

SARS-CoV-2 evolved variants optimize binding to cellular glycocalyx.

Authors: Kim SH Kearns FL Rosenfeld MA et al.

Source: Cell reports. Physical science [Cell Rep Phys Sci] 2023 Apr 19; Vol. 4 (4), pp. 101346. Date of Electronic Publication: 2023 Apr 07.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101769239 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3864 (Electronic) Linking ISSN: 26663864 NLM ISO Abbreviation: Cell Rep Phys Sci Subsets: PubMed not MEDLINE

Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.

Authors: Moghadasi SA Heilmann E Khalil AM et al.

Source: Science advances [Sci Adv] 2023 Mar 29; Vol. 9 (13), pp. eade8778. Date of Electronic Publication: 2023 Mar 29.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection.

Authors: Oh CK Nakamura T Beutler N et al.

Source: Nature chemical biology [Nat Chem Biol] 2023 Mar; Vol. 19 (3), pp. 275-283. Date of Electronic Publication: 2022 Sep 29.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.

Authors: Chongsaritsinsuk J Steigmeyer AD Mahoney KE et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Feb 03. Date of Electronic Publication: 2023 Feb 03.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

The Good, the Bad, and the Ugly: "HiPen", a New Dataset for Validating (S)QM/MM Free Energy Simulations.

Authors: Kearns FL Warrensford L Boresch S et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2019 Feb 14; Vol. 24 (4). Date of Electronic Publication: 2019 Feb 14.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.

Authors: Moghadasi SA Heilmann E Khalil AM et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2022 Dec 26. Date of Electronic Publication: 2022 Dec 26.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Spike-heparan sulfate interactions in SARS-CoV-2 infection.

Authors: Kearns FL Sandoval DR Casalino L et al.

Source: Current opinion in structural biology [Curr Opin Struct Biol] 2022 Oct; Vol. 76, pp. 102439. Date of Electronic Publication: 2022 Jul 06.

Publication Type: Journal Article; Review; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9107784 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-033X (Electronic) Linking ISSN: 0959440X NLM ISO Abbreviation: Curr Opin Struct Biol Subsets: MEDLINE