Search Results - "Keun HC"

Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants.

Authors: Stratakis N Anguita-Ruiz A Fabbri L et al.

Source: Nature communications [Nat Commun] 2025 Jan 14; Vol. 16 (1), pp. 654. Date of Electronic Publication: 2025 Jan 14.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Exploiting the polypharmacology of alectinib for synergistic RNA splicing disruption with RBM39 degraders.

Authors: Ma Y Poon E Jin C et al.

Source: Cell reports [Cell Rep] 2026 Jan 27; Vol. 45 (1), pp. 116784. Date of Electronic Publication: 2026 Jan 08.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

The exit of naive pluripotency contains a metabolism-induced checkpoint for telomere homeostasis.

Authors: de Souza RA Barneda D Karimlou D et al.

Source: Cell reports [Cell Rep] 2025 Dec 23; Vol. 44 (12), pp. 116654. Date of Electronic Publication: 2025 Dec 11.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

RAS/PI3K pathway mutations sensitise epithelial ovarian cancer cells to a PARP/NAMPT inhibitor combination.

Authors: Gruet M Xu Y An L et al.

Source: Communications biology [Commun Biol] 2025 Dec 19; Vol. 9 (1), pp. 6. Date of Electronic Publication: 2025 Dec 19.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition.

Authors: Fogal V Michopoulos F Jarnuczak AF et al.

Source: Archives of toxicology [Arch Toxicol] 2024 Aug; Vol. 98 (8), pp. 2589-2603. Date of Electronic Publication: 2024 May 17.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE

Prenatal Exposure to Chemical Mixtures and Metabolic Syndrome Risk in Children.

Authors: Güil-Oumrait N Stratakis N Maitre L et al.

Source: JAMA network open [JAMA Netw Open] 2024 May 01; Vol. 7 (5), pp. e2412040. Date of Electronic Publication: 2024 May 01.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE

The potential and challenges of targeting MTAP-negative cancers beyond synthetic lethality.

Authors: Bray C Balcells C McNeish IA et al.

Source: Frontiers in oncology [Front Oncol] 2023 Sep 19; Vol. 13, pp. 1264785. Date of Electronic Publication: 2023 Sep 19 (Print Publication: 2023).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE

Associations of four biological age markers with child development: A multi-omic analysis in the European HELIX cohort.

Authors: Robinson O Lau CE Joo S et al.

Source: ELife [Elife] 2023 Jun 06; Vol. 12. Date of Electronic Publication: 2023 Jun 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

miR-22-enriched breast cancer cells display repressed glycolytic metabolism, increased glycogen synthesis, and reduced survival in low glucose conditions.

Authors: Koufaris C Papandreou ME Ellis JK et al.

Source: Molecular biology reports [Mol Biol Rep] 2023 Jun; Vol. 50 (6), pp. 5185-5193. Date of Electronic Publication: 2023 Apr 29.

Publication Type: Journal Article

Journal Info: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE

Multi-omics signatures of the human early life exposome.

Authors: Maitre L Bustamante M Hernández-Ferrer C et al.

Source: Nature communications [Nat Commun] 2022 Nov 21; Vol. 13 (1), pp. 7024. Date of Electronic Publication: 2022 Nov 21.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

PTEN Loss Shapes Macrophage Dynamics in High-Grade Serous Ovarian Carcinoma.

Authors: Spear S Le Saux O Mirza HB et al.

Source: Cancer research [Cancer Res] 2024 Nov 15; Vol. 84 (22), pp. 3772-3787.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

RNA-binding motif protein 39 (RBM39): An emerging cancer target.

Authors: Xu Y Nijhuis A Keun HC

Source: British journal of pharmacology [Br J Pharmacol] 2022 Jun; Vol. 179 (12), pp. 2795-2812. Date of Electronic Publication: 2021 Jan 03.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma.

Authors: Nijhuis A Sikka A Yogev O et al.

Source: Nature communications [Nat Commun] 2022 Mar 16; Vol. 13 (1), pp. 1380. Date of Electronic Publication: 2022 Mar 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Urinary metabolic biomarkers of diet quality in European children are associated with metabolic health.

Authors: Stratakis N Siskos AP Papadopoulou E et al.

Source: ELife [Elife] 2022 Jan 25; Vol. 11. Date of Electronic Publication: 2022 Jan 25.

Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Editorial overview: Recent advances in metabolomics.

Authors: McCullagh JSO Keun HC

Source: Current opinion in chemical biology [Curr Opin Chem Biol] 2024 Aug; Vol. 81, pp. 102498. Date of Electronic Publication: 2024 Jul 08.

Publication Type: Editorial; Introductory Journal Article

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9811312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0402 (Electronic) Linking ISSN: 13675931 NLM ISO Abbreviation: Curr Opin Chem Biol Subsets: MEDLINE

Safety and Preliminary Efficacy of Pembrolizumab Following Transarterial Chemoembolization for Hepatocellular Carcinoma: The PETAL Phase Ib Study.

Authors: Pinato DJ D'Alessio A Fulgenzi CAM et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Jun 03; Vol. 30 (11), pp. 2433-2443.

Publication Type: Journal Article; Clinical Trial, Phase I; Multicenter Study

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Chemical tools for profiling the intracellular ADP-ribosylated proteome.

Authors: Draganov SD Gruet MJ Conole D et al.

Source: RSC chemical biology [RSC Chem Biol] 2024 May 22; Vol. 5 (7), pp. 640-651. Date of Electronic Publication: 2024 May 22 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101768727 Publication Model: eCollection Cited Medium: Internet ISSN: 2633-0679 (Electronic) Linking ISSN: 26330679 NLM ISO Abbreviation: RSC Chem Biol Subsets: PubMed not MEDLINE

Blurred lines: Crossing the boundaries between the chemical exposome and the metabolome.

Authors: Balcells C Xu Y Gil-Solsona R et al.

Source: Current opinion in chemical biology [Curr Opin Chem Biol] 2024 Feb; Vol. 78, pp. 102407. Date of Electronic Publication: 2023 Dec 11.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9811312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0402 (Electronic) Linking ISSN: 13675931 NLM ISO Abbreviation: Curr Opin Chem Biol Subsets: MEDLINE

Variability of multi-omics profiles in a population-based child cohort.

Authors: Gallego-Paüls M Hernández-Ferrer C Bustamante M et al.

Source: BMC medicine [BMC Med] 2021 Jul 22; Vol. 19 (1), pp. 166. Date of Electronic Publication: 2021 Jul 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE

Enhanced triacylglycerol catabolism by carboxylesterase 1 promotes aggressive colorectal carcinoma.

Authors: Capece D D'Andrea D Begalli F et al.

Source: The Journal of clinical investigation [J Clin Invest] 2021 Jun 01; Vol. 131 (11).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE