Search Results - "Keywood C"

Efficacy, tolerability and pharmacokinetics of a modified release formulation of ADX10059, a negative allosteric modulator of metabotropic glutamate receptor 5: an esophageal pH-impedance study in healthy subjects.

Authors: ZERBIB, F. KEYWOOD, C. STRABACH, G.

Source: Neurogastroenterology & Motility. Aug2010, Vol. 22 Issue 8, p859-e231. 8p. 1 Diagram, 3 Charts, 2 Graphs.

A proof-of-concept study evaluating the effect of ADX10059, a metabotropic glutamate receptor-5 negative allosteric modulator, on acid exposure and symptoms in gastro-oesophageal reflux disease.

Authors: Keywood, C. Wakefield, M. Tack, J.

Source: Gut (0017-5749). Sep2009, Vol. 58 Issue 9, p1192-1199. 8p. 1 Diagram, 4 Charts, 3 Graphs.

Transient lower oesophageal sphincter relaxation reducers - have we hit a brick wall? authors' reply.

Authors: Zerbib, F. Keywood, C.

Source: Alimentary Pharmacology & Therapeutics. Jun2011, Vol. 33 Issue 11, p1257-1258. 2p.

Comparison of Therapeutic Gain With Therapeutic Ratio for the Assessment of Selective 5HT1B/1D Agonist Efficacy in Migraine.

Authors: Fox AW Keywood C Sheftell FD et al.

Source: Headache: The Journal of Head & Face Pain. Jul2002, Vol. 42 Issue 7, p680-688. 9p.

Clinical Pharmacokinetics of Frovatriptan.

Authors: Buchan, P Keywood, C Wade, A et al.

Source: Headache: The Journal of Head & Face Pain. Apr2002 Supplement 2, Vol. 42, p54-62. 9p.

Subjects: Serotonin, Pharmacokinetics, Isoenzymes, Cytochrome P-450

Clinical Efficacy of Frovatriptan: Placebo-Controlled Studies.

Authors: Ryan, R Géraud, G Goldstein, J et al.

Source: Headache: The Journal of Head & Face Pain. Apr2002 Supplement 2, Vol. 42, p84-92. 9p.

Subjects: Serotonin, Headache treatment, Migraine

Frovatriptan for the Acute Treatment of Migraine: A Dose-Finding Study.

Authors: Goldstein, Jerome Keywood, C on behalf of the 251/96/14 Study Group

Source: Headache: The Journal of Head & Face Pain. Jan2002, Vol. 42 Issue 1, p41-48. 8p.

Subjects: Migraine, Headache treatment

2.231 ADX48621, A MGLUR5 NEGATIVE ALLOSTERIC MODULATOR ALLEVIATES L-DOPA-INDUCED CHOREA AND DYSTONIA IN THE MPTP MACAQUE MODEL OF PARKINSON'S DISEASE

Authors: Keywood, C. Bezard, E. Hill, M. et al.

Source: Parkinsonism & Related Disorders. Jan2012, Vol. 18, pS122-S122. 1p.

1.139 ANTI-PARKINSONIAN EFFECTS OF ADX48621 A MGLUR5 NEGATIVE ALLOSTERIC MODULATOR (NAM), IN THE RAT HALOPERIDOL INDUCED CATALEPSY MODEL

Authors: Keywood, C. Girard, F. Poli, S. et al.

Source: Parkinsonism & Related Disorders. Jan2012, Vol. 18, pS45-S45. 1p.

Randomised clinical trial: effects of monotherapy with ADX10059, a mGluR5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux disease.

Authors: Zerbib, F. Bruley des Varannes, S. Roman, S. et al.

Source: Alimentary Pharmacology & Therapeutics. Apr2011, Vol. 33 Issue 8, p911-921. 11p. 1 Diagram, 4 Charts, 3 Graphs.

Food and Drug Administration Public Workshop Summary-Addressing Challenges in Inhaled Antifungal Drug Development.

Authors: Jjingo CJ Bala S Waack U et al.

Source: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2024 Jun 14; Vol. 78 (6), pp. 1564-1570.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE

A Phase 2A Trial of the Novel mGluR5-Negative Allosteric Modulator Dipraglurant for Levodopa-Induced Dyskinesia in Parkinson's Disease.

Authors: Tison F Keywood C Wakefield M et al.

Source: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2016 Sep; Vol. 31 (9), pp. 1373-80. Date of Electronic Publication: 2016 May 23.

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8610688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8257 (Electronic) Linking ISSN: 08853185 NLM ISO Abbreviation: Mov Disord Subsets: MEDLINE

Therapeutic innovation in Parkinson's disease: a 2020 update on disease-modifying approaches.

Authors: Colombo D Pnevmatikou P Melloni E et al.

Source: Expert review of neurotherapeutics [Expert Rev Neurother] 2020 Oct; Vol. 20 (10), pp. 1047-1064. Date of Electronic Publication: 2020 Aug 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101129944 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8360 (Electronic) Linking ISSN: 14737175 NLM ISO Abbreviation: Expert Rev Neurother Subsets: MEDLINE

Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study.

Authors: Svenningsson P Rosenblad C Af Edholm Arvidsson K et al.

Source: Brain : a journal of neurology [Brain] 2015 Apr; Vol. 138 (Pt 4), pp. 963-73. Date of Electronic Publication: 2015 Feb 10.

Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

The mGluR5 negative allosteric modulator dipraglurant reduces dyskinesia in the MPTP macaque model.

Authors: Bezard E Pioli EY Li Q et al.

Source: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2014 Jul; Vol. 29 (8), pp. 1074-9. Date of Electronic Publication: 2014 May 27.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8610688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8257 (Electronic) Linking ISSN: 08853185 NLM ISO Abbreviation: Mov Disord Subsets: MEDLINE

Effects of safinamide on the glutamatergic striatal network in experimental Parkinson's disease.

Authors: Sciaccaluga M Mazzocchetti P Bastioli G et al.

Source: Neuropharmacology [Neuropharmacology] 2020 Jun 15; Vol. 170, pp. 108024. Date of Electronic Publication: 2020 Mar 03.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo.

Authors: Desaphy JF Farinato A Altamura C et al.

Source: Experimental neurology [Exp Neurol] 2020 Jun; Vol. 328, pp. 113287. Date of Electronic Publication: 2020 Mar 20.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2430 (Electronic) Linking ISSN: 00144886 NLM ISO Abbreviation: Exp Neurol Subsets: MEDLINE

Safinamide inhibits in vivo glutamate release in a rat model of Parkinson's disease.

Authors: Pisanò CA Brugnoli A Novello S et al.

Source: Neuropharmacology [Neuropharmacology] 2020 May 01; Vol. 167, pp. 108006. Date of Electronic Publication: 2020 Feb 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

Rapid responders to frovatriptan in acute migraine treatment: results from a long-term, open-label study.

Authors: Spierings EL Keywood C

Source: Pain medicine (Malden, Mass.) [Pain Med] 2009 May-Jun; Vol. 10 (4), pp. 633-8. Date of Electronic Publication: 2009 Apr 22.

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: published by Oxford University Press on behalf of the American Academy of Pain Medicine Country of Publication: England NLM ID: 100894201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-4637 (Electronic) Linking ISSN: 15262375 NLM ISO Abbreviation: Pain Med Subsets: MEDLINE

Topical eutectic mixture for premature ejaculation (TEMPE): a novel aerosol-delivery form of lidocaine-prilocaine for treating premature ejaculation.

Authors: Dinsmore WW Hackett G Goldmeier D et al.

Source: BJU international [BJU Int] 2007 Feb; Vol. 99 (2), pp. 369-75. Date of Electronic Publication: 2006 Nov 24.

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Blackwell Science Country of Publication: England NLM ID: 100886721 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1464-4096 (Print) Linking ISSN: 14644096 NLM ISO Abbreviation: BJU Int Subsets: MEDLINE