Search Results - "Klichinsky M"

CD33-specific chimeric antigen receptor T cells exhibit potent preclinical activity against human acute myeloid leukemia.

Authors: Kenderian, S S Ruella, M Shestova, O et al.

Source: Leukemia (08876924). Aug2015, Vol. 29 Issue 8, p1637-1647. 11p. 7 Graphs.

15 - Hematopoietic Stem/Progenitor Cells and Engineering: A PHASE 1, FIRST IN HUMAN (FIH) STUDY OF ADENOVIRALLY TRANSDUCED AUTOLOGOUS MACROPHAGES ENGINEERED TO CONTAIN AN ANTI-HER2 CHIMERIC ANTIGEN RECEPTOR (CAR) IN SUBJECTS WITH HER2 OVEREXPRESSING SOLID TUMORS

Authors: Abdou, Y. Yuan, Y. Ueno, N.T. et al.

Source: Cytotherapy (Elsevier Inc.). 2022 Supplement, Vol. 24 Issue 5, pS26-S27. 2p.

563TiP A phase I, first in human (FIH) study of adenovirally transduced autologous macrophages engineered to contain an anti-HER2 chimeric antigen receptor (CAR) in subjects with HER2 overexpressing solid tumors.

Authors: Binder, K.R. Barton, D. Ronczka, A. et al.

Source: Annals of Oncology. 2021 Supplement 5, Vol. 32, pS618-S618. 1p.

a phase 1, first in human (FIH) study of adenovirally transduced autologous macrophages engineered to contain an anti-HER2 chimeric antigen receptor (CAR) in subjects with HER2 overexpressing solid tumors.

Authors: Bauml, J. Barton, D. Ronczka, A. et al.

Source: Cytotherapy (Elsevier Inc.). 2021 Supplement, Vol. 23 Issue 5, pS95-S95. 1p.

Impaired TIM4-mediated efferocytosis by liver macrophages contributes to fibrosis in metabolic dysfunction-associated steatohepatitis.

Authors: Shi H Wang X Sloas C et al.

Source: Science translational medicine [Sci Transl Med] 2025 Sep 10; Vol. 17 (815), pp. eadv2106. Date of Electronic Publication: 2025 Sep 10.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

In vivo chimeric antigen receptor (CAR)-T cell therapy.

Authors: Bot A Scharenberg A Friedman K et al.

Source: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2026 Feb; Vol. 25 (2), pp. 116-137. Date of Electronic Publication: 2025 Sep 30.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124171 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-1784 (Electronic) Linking ISSN: 14741776 NLM ISO Abbreviation: Nat Rev Drug Discov Subsets: MEDLINE

Author Correction: Chimeric antigen receptor macrophages (CAR-M) sensitize HER2+ solid tumors to PD1 blockade in pre-clinical models.

Authors: Pierini S Gabbasov R Oliveira-Nunes MC et al.

Source: Nature communications [Nat Commun] 2025 Mar 19; Vol. 16 (1), pp. 2692. Date of Electronic Publication: 2025 Mar 19.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE; PubMed not MEDLINE

Chimeric antigen receptor macrophages (CAR-M) sensitize HER2+ solid tumors to PD1 blockade in pre-clinical models.

Authors: Pierini S Gabbasov R Oliveira-Nunes MC et al.

Source: Nature communications [Nat Commun] 2025 Jan 15; Vol. 16 (1), pp. 706. Date of Electronic Publication: 2025 Jan 15.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

CAR-macrophage therapy for HER2-overexpressing advanced solid tumors: a phase 1 trial.

Authors: Reiss KA Angelos MG Dees EC et al.

Source: Nature medicine [Nat Med] 2025 Apr; Vol. 31 (4), pp. 1171-1182. Date of Electronic Publication: 2025 Feb 07.

Publication Type: Journal Article; Clinical Trial, Phase I

Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

Engineered CAR-Macrophages as Adoptive Immunotherapies for Solid Tumors.

Authors: Sloas C Gill S Klichinsky M

Source: Frontiers in immunology [Front Immunol] 2021 Nov 24; Vol. 12, pp. 783305. Date of Electronic Publication: 2021 Nov 24 (Print Publication: 2021).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Expression of inducible factors reprograms CAR-T cells for enhanced function and safety.

Authors: Smole A Benton A Poussin MA et al.

Source: Cancer cell [Cancer Cell] 2022 Dec 12; Vol. 40 (12), pp. 1470-1487.e7.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies.

Authors: Ruella M Barrett DM Kenderian SS et al.

Source: The Journal of clinical investigation [J Clin Invest] 2016 Oct 03; Vol. 126 (10), pp. 3814-3826. Date of Electronic Publication: 2016 Aug 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

Macrophage-Based Approaches for Cancer Immunotherapy.

Authors: Anderson NR Minutolo NG Gill S et al.

Source: Cancer research [Cancer Res] 2021 Mar 01; Vol. 81 (5), pp. 1201-1208. Date of Electronic Publication: 2020 Nov 17.

Publication Type: Journal Article; Review

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Human chimeric antigen receptor macrophages for cancer immunotherapy.

Authors: Klichinsky M Ruella M Shestova O et al.

Source: Nature biotechnology [Nat Biotechnol] 2020 Aug; Vol. 38 (8), pp. 947-953. Date of Electronic Publication: 2020 Mar 23.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

A fungal protease allergen provokes airway hyper-responsiveness in asthma.

Authors: Balenga NA Klichinsky M Xie Z et al.

Source: Nature communications [Nat Commun] 2015 Apr 13; Vol. 6, pp. 6763. Date of Electronic Publication: 2015 Apr 13.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

EBV latency types adopt alternative chromatin conformations.

Authors: Tempera I Klichinsky M Lieberman PM

Source: PLoS pathogens [PLoS Pathog] 2011 Jul; Vol. 7 (7), pp. e1002180. Date of Electronic Publication: 2011 Jul 28.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell.

Authors: Ruella M Xu J Barrett DM et al.

Source: Nature medicine [Nat Med] 2018 Oct; Vol. 24 (10), pp. 1499-1503. Date of Electronic Publication: 2018 Oct 01.

Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia.

Authors: Kim MY Yu KR Kenderian SS et al.

Source: Cell [Cell] 2018 May 31; Vol. 173 (6), pp. 1439-1453.e19. Date of Electronic Publication: 2018 May 31.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Overcoming the Immunosuppressive Tumor Microenvironment of Hodgkin Lymphoma Using Chimeric Antigen Receptor T Cells.

Authors: Ruella M Klichinsky M Kenderian SS et al.

Source: Cancer discovery [Cancer Discov] 2017 Oct; Vol. 7 (10), pp. 1154-1167. Date of Electronic Publication: 2017 Jun 02.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

Kinase inhibitor ibrutinib to prevent cytokine-release syndrome after anti-CD19 chimeric antigen receptor T cells for B-cell neoplasms.

Authors: Ruella M Kenderian SS Shestova O et al.

Source: Leukemia [Leukemia] 2017 Jan; Vol. 31 (1), pp. 246-248. Date of Electronic Publication: 2016 Sep 28.

Publication Type: Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE