Search Results - "Knust H"

Crane runway maintenance.

Authors: Knust, H. R.

Source: Iron & Steel Engineer; September 1952, Vol. 29, p84-91, 8p

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Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX(2) receptor.

Authors: Malherbe, P. Borroni, E. Gobbi, L. et al.

Source: British Journal of Pharmacology. Apr2009, Vol. 156 Issue 8, p1326-1341. 16p. 1 Diagram, 5 Charts, 9 Graphs.

Preclinical pharmacology of alogabat: a novel GABAA-α5 positive allosteric modulator targeting neurodevelopmental disorders with impaired GABAA signaling.

Authors: Cecere G Ballard TM Knoflach F et al.

Source: Frontiers in pharmacology [Front Pharmacol] 2025 Jul 21; Vol. 16, pp. 1626078. Date of Electronic Publication: 2025 Jul 21 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE

Preclinical Evaluation of ¹⁸F-RO6958948, ¹¹C-RO6931643, and ¹¹C-RO6924963 as Novel PET Radiotracers for Imaging Tau Aggregates in Alzheimer Disease.

Authors: Honer M Gobbi L Knust H et al.

Source: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2018 Apr; Vol. 59 (4), pp. 675-681. Date of Electronic Publication: 2017 Sep 28.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE

Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man.

Authors: Hipp JF Knoflach F Comley R et al.

Source: Scientific reports [Sci Rep] 2021 Apr 08; Vol. 11 (1), pp. 7700. Date of Electronic Publication: 2021 Apr 08.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

RO4938581, a novel cognitive enhancer acting at GABAA alpha5 subunit-containing receptors.

Authors: Ballard TM Knoflach F Prinssen E et al.

Source: Psychopharmacology [Psychopharmacology (Berl)] 2009 Jan; Vol. 202 (1-3), pp. 207-23. Date of Electronic Publication: 2008 Oct 21.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE

Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer's Disease with Positron Emission Tomography.

Authors: Gobbi LC Knust H Körner M et al.

Source: Journal of medicinal chemistry [J Med Chem] 2017 Sep 14; Vol. 60 (17), pp. 7350-7370. Date of Electronic Publication: 2017 Jul 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Direct photocatalytic fluorination of benzylic C-H bonds with N-fluorobenzenesulfonimide.

Authors: Nodwell MB Bagai A Halperin SD et al.

Source: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2015 Jul 28; Vol. 51 (59), pp. 11783-6.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: MEDLINE

Mapping the binding pocket of a novel, high-affinity, slow dissociating tachykinin NK3 receptor antagonist: biochemical and electrophysiological characterization.

Authors: Malherbe P Knoflach F Marcuz A et al.

Source: Neuropharmacology [Neuropharmacology] 2014 Nov; Vol. 86, pp. 259-72. Date of Electronic Publication: 2014 Aug 05.

Publication Type: Journal Article

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

Adventures in drug-like chemistry space: from oxetanes to spiroazetidines and beyond!

Authors: Rogers-Evans M Knust H Plancher JM et al.

Source: Chimia [Chimia (Aarau)] 2014; Vol. 68 (7-8), pp. 492-9.

Publication Type: Journal Article

Journal Info: Publisher: Swiss Chemical Society Country of Publication: Switzerland NLM ID: 0373152 Publication Model: Print Cited Medium: Print ISSN: 0009-4293 (Print) Linking ISSN: 00094293 NLM ISO Abbreviation: Chimia (Aarau) Subsets: MEDLINE

Conformationally restricted pyrrolidines by intramolecular [2+2] photocycloaddition reactions.

Authors: Fort DA Woltering TJ Nettekoven M et al.

Source: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2013 Apr 14; Vol. 49 (29), pp. 2989-91.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: MEDLINE

Bis(arylvinyl)pyrazines, -pyrimidines, and -pyridazines as imaging agents for tau fibrils and β-amyloid plaques in Alzheimer's disease models.

Authors: Boländer A Kieser D Voss C et al.

Source: Journal of medicinal chemistry [J Med Chem] 2012 Nov 08; Vol. 55 (21), pp. 9170-80. Date of Electronic Publication: 2012 Aug 31.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Synthesis of fluorinated tricyclic scaffolds by intramolecular [2+2] photocycloaddition reactions.

Authors: Fort DA Woltering TJ Nettekoven M et al.

Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2012 Oct 01; Vol. 51 (40), pp. 10169-72. Date of Electronic Publication: 2012 Sep 07.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: PubMed not MEDLINE

Expanding the azaspiro[3.3]heptane family: synthesis of novel highly functionalized building blocks.

Authors: Burkhard JA Guérot C Knust H et al.

Source: Organic letters [Org Lett] 2012 Jan 06; Vol. 14 (1), pp. 66-9. Date of Electronic Publication: 2011 Nov 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

Synthesis of novel angular spirocyclic azetidines.

Authors: Guérot C Tchitchanov BH Knust H et al.

Source: Organic letters [Org Lett] 2011 Feb 18; Vol. 13 (4), pp. 780-3. Date of Electronic Publication: 2011 Jan 14.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

Rational design of novel pyrrolidine derivatives as orally active neurokinin-3 receptor antagonists.

Authors: Ratni H Ballard TM Bissantz C et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2010 Nov 15; Vol. 20 (22), pp. 6735-8. Date of Electronic Publication: 2010 Sep 17.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

Synthesis and structural analysis of a new class of azaspiro[3.3]heptanes as building blocks for medicinal chemistry.

Authors: Burkhard JA Guérot C Knust H et al.

Source: Organic letters [Org Lett] 2010 May 07; Vol. 12 (9), pp. 1944-7.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

Imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepines as potent and highly selective GABAA alpha5 inverse agonists with potential for the treatment of cognitive dysfunction.

Authors: Buettelmann B Ballard TM Gasser R et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Oct 15; Vol. 19 (20), pp. 5958-61. Date of Electronic Publication: 2009 Aug 11.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA alpha5 inverse agonists for the treatment of cognitive dysfunction.

Authors: Knust H Achermann G Ballard T et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Oct 15; Vol. 19 (20), pp. 5940-4. Date of Electronic Publication: 2009 Aug 15.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE