Search Results - "Linley JE"

A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response.

Authors: Shilliday F Gancedo-Rodrigo M George G et al.

Source: Nature communications [Nat Commun] 2026 May 06. Date of Electronic Publication: 2026 May 06.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Monoclonal antibody inhibition of PAR2 reduces phenotype severity and pain in murine inflammatory bowel disease.

Authors: Ritoux A Grundy LJ Manjappa P et al.

Source: Pain reports [Pain Rep] 2026 Apr 20; Vol. 11 (3), pp. e1446. Date of Electronic Publication: 2026 Apr 20 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 101683899 Publication Model: eCollection Cited Medium: Internet ISSN: 2471-2531 (Electronic) Linking ISSN: 24712531 NLM ISO Abbreviation: Pain Rep Subsets: PubMed not MEDLINE

Efficacy of MEDI0618, a pH-dependent monoclonal antibody targeting PAR2, in preclinical models of migraine.

Authors: Kopruszinski CM Linley JE Thornton P et al.

Source: Brain : a journal of neurology [Brain] 2025 Apr 03; Vol. 148 (4), pp. 1345-1359.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

SLC45A4 is a pain gene encoding a neuronal polyamine transporter.

Authors: Middleton SJ Markússon S Åkerlund M et al.

Source: Nature [Nature] 2025 Oct; Vol. 646 (8084), pp. 404-412. Date of Electronic Publication: 2025 Aug 20.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Pain in fibrous dysplasia: identifying nociceptive mechanisms in a preclinical model.

Authors: Hopkins C de Castro LF Benthin J et al.

Source: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2025 Jun 25; Vol. 40 (7), pp. 891-903.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8610640 Publication Model: Print Cited Medium: Internet ISSN: 1523-4681 (Electronic) Linking ISSN: 08840431 NLM ISO Abbreviation: J Bone Miner Res Subsets: MEDLINE

Pregabalin Silences Oxaliplatin-Activated Sensory Neurons to Relieve Cold Allodynia.

Authors: Iseppon F Luiz AP Linley JE et al.

Source: ENeuro [eNeuro] 2023 Feb 21; Vol. 10 (2). Date of Electronic Publication: 2023 Feb 21 (Print Publication: 2023).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 101647362 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2822 (Electronic) Linking ISSN: 23732822 NLM ISO Abbreviation: eNeuro Subsets: MEDLINE

Identification of SLC45A4 as a pain gene encoding a neuronal polyamine transporter.

Authors: Middleton SJ Markússon S Åkerlund M et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 30. Date of Electronic Publication: 2024 Sep 30.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene-targeted mice.

Authors: Kanellopoulos AH Koenig J Huang H et al.

Source: The EMBO journal [EMBO J] 2018 Feb 01; Vol. 37 (3), pp. 427-445. Date of Electronic Publication: 2018 Jan 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

Calcium imaging for analgesic drug discovery.

Authors: Iseppon F Linley JE Wood JN

Source: Neurobiology of pain (Cambridge, Mass.) [Neurobiol Pain] 2022 Jan 05; Vol. 11, pp. 100083. Date of Electronic Publication: 2022 Jan 05 (Print Publication: 2022).

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 101705141 Publication Model: eCollection Cited Medium: Internet ISSN: 2452-073X (Electronic) Linking ISSN: 2452073X NLM ISO Abbreviation: Neurobiol Pain Subsets: PubMed not MEDLINE

Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia.

Authors: Koenig J Werdehausen R Linley JE et al.

Source: PloS one [PLoS One] 2015 Jun 02; Vol. 10 (6), pp. e0128830. Date of Electronic Publication: 2015 Jun 02 (Print Publication: 2015).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Recombinant expression and in vitro characterisation of active Huwentoxin-IV.

Authors: Sermadiras I Revell J Linley JE et al.

Source: PloS one [PLoS One] 2013 Dec 06; Vol. 8 (12), pp. e83202. Date of Electronic Publication: 2013 Dec 06 (Print Publication: 2013).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Novel mutations mapping to the fourth sodium channel domain of Nav1.7 result in variable clinical manifestations of primary erythromelalgia.

Authors: Cregg R Laguda B Werdehausen R et al.

Source: Neuromolecular medicine [Neuromolecular Med] 2013 Jun; Vol. 15 (2), pp. 265-78. Date of Electronic Publication: 2013 Jan 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 101135365 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1174 (Electronic) Linking ISSN: 15351084 NLM ISO Abbreviation: Neuromolecular Med Subsets: MEDLINE

A role for Piezo2 in EPAC1-dependent mechanical allodynia.

Authors: Eijkelkamp N Linley JE Torres JM et al.

Source: Nature communications [Nat Commun] 2013; Vol. 4, pp. 1682.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Neurological perspectives on voltage-gated sodium channels.

Authors: Eijkelkamp N Linley JE Baker MD et al.

Source: Brain : a journal of neurology [Brain] 2012 Sep; Vol. 135 (Pt 9), pp. 2585-612.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

M channel enhancers and physiological M channel block.

Authors: Linley JE Pettinger L Huang D et al.

Source: The Journal of physiology [J Physiol] 2012 Feb 15; Vol. 590 (4), pp. 793-807. Date of Electronic Publication: 2011 Dec 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

Potential role of reduced basolateral potassium (IKCa3.1) channel expression in the pathogenesis of diarrhoea in ulcerative colitis.

Authors: Al-Hazza A Linley JE Aziz Q et al.

Source: The Journal of pathology [J Pathol] 2012 Feb; Vol. 226 (3), pp. 463-70. Date of Electronic Publication: 2011 Oct 18.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE

Understanding inflammatory pain: ion channels contributing to acute and chronic nociception.

Authors: Linley JE Rose K Ooi L et al.

Source: Pflugers Archiv : European journal of physiology [Pflugers Arch] 2010 Apr; Vol. 459 (5), pp. 657-69. Date of Electronic Publication: 2010 Feb 17.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 0154720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2013 (Electronic) Linking ISSN: 00316768 NLM ISO Abbreviation: Pflugers Arch Subsets: MEDLINE

The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl- channels.

Authors: Liu B Linley JE Du X et al.

Source: The Journal of clinical investigation [J Clin Invest] 2010 Apr; Vol. 120 (4), pp. 1240-52. Date of Electronic Publication: 2010 Mar 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain.

Authors: Williams WA Linley JE Jones CA et al.

Source: Pain [Pain] 2019 Sep; Vol. 160 (9), pp. 1989-2003.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7508686 Publication Model: Print Cited Medium: Internet ISSN: 1872-6623 (Electronic) Linking ISSN: 03043959 NLM ISO Abbreviation: Pain Subsets: MEDLINE

A voltage-dependent Ca2+ influx pathway regulates the Ca2+-dependent Cl(-) conductance of renal IMCD-3 cells.

Authors: Linley JE Boese SH Simmons NL et al.

Source: The Journal of membrane biology [J Membr Biol] 2009 Jul; Vol. 230 (2), pp. 57-68. Date of Electronic Publication: 2009 Jun 28.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 0211301 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1424 (Electronic) Linking ISSN: 00222631 NLM ISO Abbreviation: J Membr Biol Subsets: MEDLINE