Search Results - "Luk KC"

Testing an inverse link between limbic alpha-synucleinopathy and myelin markers in mice and humans.

Authors: Clark RN Landes RE Abbas M et al.

Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2026 Feb 17; Vol. 12 (1). Date of Electronic Publication: 2026 Feb 17.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE

Synphilin-1 modulates alpha-synuclein assembly, release and uptake.

Authors: Lázaro DF Amen T Gerhardt E et al.

Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2025 Nov 20; Vol. 11 (1), pp. 326. Date of Electronic Publication: 2025 Nov 20.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE

NERINE reveals rare variant associations in gene networks across phenotypes and implicates an SNCA-PRL-LRRK2 subnetwork in Parkinson's disease.

Authors: Nazeen S Wang X Morrow AR et al.

Source: Cell genomics [Cell Genom] 2026 Jun 22, pp. 101284. Date of Electronic Publication: 2026 Jun 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918284260106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-979X (Electronic) Linking ISSN: 2666979X NLM ISO Abbreviation: Cell Genom Subsets: MEDLINE

IFNγ alters the aberrant phenotype of α-synuclein-treated microglia reducing the detrimental impact of their secretome on dopaminergic neurons.

Authors: Niskanen J Hakosalo V Hämäläinen W et al.

Source: Neuroscience [Neuroscience] 2026 May 25; Vol. 603, pp. 201-213. Date of Electronic Publication: 2026 Mar 28.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

Secreted GPNMB enhances uptake of fibrillar alpha-synuclein in a non-cell-autonomous process that can be blocked by anti-GPNMB antibodies.

Authors: Carceles-Cordon M Brody EM Boucher ML et al.

Source: Neuron [Neuron] 2026 May 12. Date of Electronic Publication: 2026 May 12.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

Cell vulnerability within the sublaterodorsal tegmental nucleus underlies REM sleep behaviour disorder in prodromal α-synucleinopathy.

Authors: Luke R Yoo HS McKenna D et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 01. Date of Electronic Publication: 2026 May 01.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Complement Dysregulation During the Early Phases of Synucleinopathy.

Authors: Khan H Gifford M Kordbacheh A et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 30. Date of Electronic Publication: 2026 Apr 30.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Intrastriatal injection of alpha-synuclein preformed fibrils to rats results in L-DOPA reversible sensorimotor impairments and alterations in non-motor function.

Authors: Fleming SM Scott S Hamad EJ et al.

Source: Frontiers in neuroscience [Front Neurosci] 2025 Apr 01; Vol. 19, pp. 1556447. Date of Electronic Publication: 2025 Apr 01 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101478481 Publication Model: eCollection Cited Medium: Print ISSN: 1662-4548 (Print) Linking ISSN: 1662453X NLM ISO Abbreviation: Front Neurosci Subsets: PubMed not MEDLINE

Clinically advanced NLRP3 inhibitor modulates microglial transcriptome and alleviates α-synuclein-induced progression of parkinsonism.

Authors: Luque M Matic M Heras-Garvin A et al.

Source: Journal of neuroinflammation [J Neuroinflammation] 2026 Jan 31; Vol. 23 (1). Date of Electronic Publication: 2026 Jan 31.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE

Unraveling the intersection of aging and Parkinson's disease: a collaborative roadmap for advancing research models.

Authors: Schmidt MY Cuervo AM Double KL et al.

Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2026 Jan 16; Vol. 12 (1), pp. 28. Date of Electronic Publication: 2026 Jan 16.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE

Uptake of alpha-synuclein preformed fibrils is suppressed by inflammation and induces an aberrant phenotype in human microglia.

Authors: Niskanen J Peltonen S Ohtonen S et al.

Source: Glia [Glia] 2025 Jan; Vol. 73 (1), pp. 159-174. Date of Electronic Publication: 2024 Oct 22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8806785 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1136 (Electronic) Linking ISSN: 08941491 NLM ISO Abbreviation: Glia Subsets: MEDLINE

Targeting Endogenous Tau in Seeded Tauopathy Models Inhibits Tau Spread.

Authors: Jang E Hoxha K Mozier D et al.

Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2024 Nov 27; Vol. 44 (48). Date of Electronic Publication: 2024 Nov 27.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

Human microglia reduce alpha-synuclein aggregation and are neuroprotective in adult mouse brain.

Authors: Albert K Peltonen S Vanne A et al.

Source: Brain, behavior, and immunity [Brain Behav Immun] 2025 Nov; Vol. 130, pp. 106097. Date of Electronic Publication: 2025 Sep 03.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE

Current insights and assumptions on α-synuclein in Lewy body disease.

Authors: Leak RK Clark RN Abbas M et al.

Source: Acta neuropathologica [Acta Neuropathol] 2024 Aug 14; Vol. 148 (1), pp. 18. Date of Electronic Publication: 2024 Aug 14.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

Deficits in basal and evoked striatal dopamine release following alpha-synuclein preformed fibril injection: An in vivo microdialysis study.

Authors: Centner A Del Priore I Chambers N et al.

Source: The European journal of neuroscience [Eur J Neurosci] 2024 Apr; Vol. 59 (7), pp. 1585-1603. Date of Electronic Publication: 2024 Feb 14.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: France NLM ID: 8918110 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-9568 (Electronic) Linking ISSN: 0953816X NLM ISO Abbreviation: Eur J Neurosci Subsets: MEDLINE

Development and Validation of Three Automated High-Throughput Molecular Tests to Detect Monkeypox Virus Infections.

Authors: Anderson M Hodges A Luk KC et al.

Source: The Journal of infectious diseases [J Infect Dis] 2024 Mar 26; Vol. 229 (Supplement_2), pp. S137-S143.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE

MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons.

Authors: Xu H Qiu Q Hu P et al.

Source: Acta neuropathologica [Acta Neuropathol] 2024 Mar 12; Vol. 147 (1), pp. 55. Date of Electronic Publication: 2024 Mar 12.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils.

Authors: Patterson JR Kochmanski J Stoll AC et al.

Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2024 Jan 03; Vol. 10 (1), pp. 7. Date of Electronic Publication: 2024 Jan 03.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE

Combining fibril-induced alpha-synuclein aggregation and 6-hydroxydopamine in a mouse model of Parkinson's disease and the effect of cerebral dopamine neurotrophic factor on the induced neurodegeneration.

Authors: Singh A Panhelainen A Reunanen S et al.

Source: The European journal of neuroscience [Eur J Neurosci] 2024 Jan; Vol. 59 (1), pp. 132-153. Date of Electronic Publication: 2023 Dec 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: France NLM ID: 8918110 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-9568 (Electronic) Linking ISSN: 0953816X NLM ISO Abbreviation: Eur J Neurosci Subsets: MEDLINE

Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice.

Authors: Boyd SL Kuhn NC Patterson JR et al.

Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2023 Oct 30; Vol. 196 (1), pp. 99-111.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE