Search Results - "Maia de Oliveira T"

RAF inhibitors activate the integrated stress response by direct activation of GCN2.

Authors: Gilley R Kidger AM Neill G et al.

Source: Nature communications [Nat Commun] 2025 Nov 17; Vol. 16 (1), pp. 10033. Date of Electronic Publication: 2025 Nov 17.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

The rise and fall of SARM1 base-exchange inhibitors.

Authors: Lundbäck T Chandrasekar V Gu C et al.

Source: Communications chemistry [Commun Chem] 2026 May 19; Vol. 9 (1). Date of Electronic Publication: 2026 May 19.

Publication Type: Journal Article

Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101725670 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3669 (Electronic) Linking ISSN: 23993669 NLM ISO Abbreviation: Commun Chem Subsets: PubMed not MEDLINE

A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response.

Authors: Shilliday F Gancedo-Rodrigo M George G et al.

Source: Nature communications [Nat Commun] 2026 May 06. Date of Electronic Publication: 2026 May 06.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Identification and Characterization of Novel Inhibitors of Human Poly(ADP-Ribose) Polymerase-1.

Authors: Morgan, Ibrahim Rennert, Robert Berger, Robert et al.

Source: Molecules. Jul2025, Vol. 30 Issue 13, p2728. 19p.

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Interplay Between Poly(ADP-ribosyl)ation and Specific Inner Cellular Events That Suggest Combination Strategies for Overcoming PARP Inhibitor Resistance.

Authors: Xu, Lingwen Kong, Xiangyu Zhang, Bin et al.

Source: Pharmaceutics. Mar2026, Vol. 18 Issue 3, p355. 46p.

Molecular Insights and Therapeutic Innovations in Cervical Cancer: Emerging Drug Targets.

Authors: Debnath, Abhijit Singh, Rajesh Kumar Mazumder, Rupa et al.

Source: Advances in Pharmacological & Pharmaceutical Sciences. 1/16/2026, Vol. 2026, p1-26. 26p.

PARP3 Affects Nucleosome Compaction Regulation.

Authors: Ukraintsev, Alexander Kutuzov, Mikhail Belousova, Ekaterina et al.

Source: International Journal of Molecular Sciences. May2023, Vol. 24 Issue 10, p9042. 25p.

Unlocking the Therapeutic Potential of DNA-PKcs in Cancer: Comprehensive Insights into Mechanisms and Clinical Applications.

Authors: Zheng, Tong Sun, Chao Yun, Cijun et al.

Source: Cancers. Sep2025, Vol. 17 Issue 17, p2787. 23p.

Isolation of New Chemical Modulators of the Interaction Between HIV-1 Integrase and the Cellular Restriction Factor GCN2.

Authors: Torres, Chloé Lagadec, Floriane Basyuk, Eugenia et al.

Source: Viruses (1999-4915). Aug2025, Vol. 17 Issue 8, p1138. 23p.

The Crucial Role of NAD⁺ in Mitochondrial Metabolic Regulation.

Authors: Mishra, Kumudesh Kakhlon, Or

Source: Biocell. 2025, Vol. 49 Issue 7, p1101-1123. 23p.

Computational prediction of potential aggravating mechanisms of polyethylene terephthalate microplastics in diabetic foot ulcers: An integrated in silico approach combining network toxicology, bioinformatics, machine learning, and molecular dynamics simulations.

Authors: Li D Ma Z Li Z et al.

Source: Medicine [Medicine (Baltimore)] 2026 Jun 05; Vol. 105 (23), pp. e49208.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE

Nicotinamide phosphoribosyltransferase in NAD⁺ metabolism: physiological and pathophysiological implications.

Authors: Zhang W Ren H Chen W et al.

Source: Cell death discovery [Cell Death Discov] 2025 Aug 08; Vol. 11 (1), pp. 371. Date of Electronic Publication: 2025 Aug 08.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE

Machine learning-based screening and molecular simulations for discovering novel PARP-1 inhibitors targeting DNA repair mechanisms for breast cancer therapy.

Authors: Shahab M Waqas M Fahira A et al.

Source: Molecular diversity [Mol Divers] 2025 Aug; Vol. 29 (4), pp. 3323-3343. Date of Electronic Publication: 2025 Feb 03.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

PARP-1 as a novel target in endocrine-resistant breast cancer.

Authors: Zicarelli, Azzurra Talia, Marianna Lainé, Muriel et al.

Source: Journal of Experimental & Clinical Cancer Research (17569966). 6/16/2025, Vol. 44 Issue 1, p1-19. 19p.

Clinical approaches to overcome PARP inhibitor resistance.

Authors: Zou, Yutian Zhang, Hanqi Chen, Pangzhou et al.

Source: Molecular Cancer. 5/30/2025, Vol. 24 Issue 1, p1-25. 25p.

Role of PARP Inhibitors: A New Hope for Breast Cancer Therapy.

Authors: De, Kamalendu Jana, Malabendu Chowdhury, Bhabadeb et al.

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 6, p2773. 27p.

Targeting selective inhibitors of PARPs in drug discovery and development.

Authors: Duan, Maolin Gao, Jing Li, Jiajin et al.

Source: Medicinal Chemistry Research. Oct2024, Vol. 33 Issue 10, p1734-1756. 23p.

Human PARP1 Facilitates Transcription through a Nucleosome and Histone Displacement by Pol II In Vitro.

Authors: Kotova, Elena Y. Hsieh, Fu-Kai Chang, Han-Wen et al.

Source: International Journal of Molecular Sciences. Jul2022, Vol. 23 Issue 13, p7107-N.PAG. 15p.

PARP-1 Expression and BRCA1 Mutations in Breast Cancer Patients' CTCs.

Authors: Sklias, Thodoris Vardas, Vasileios Pantazaka, Evangelia et al.

Source: Cancers. Apr2022, Vol. 14 Issue 7, p1731. 13p.