Search Results - "Myant KB"

A progeria syndrome links DNA hypermethylation to age-related pathology.

Authors: Sarni D Neary G Carroll PL et al.

Source: Nature genetics [Nat Genet] 2026 Jun 12. Date of Electronic Publication: 2026 Jun 12.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

DP103 as a critical modulator of Wnt signaling and cancer stemness: implications for precision treatment in triple negative breast cancer.

Authors: Cai W Pohl SÖ Lai X et al.

Source: Cell death & disease [Cell Death Dis] 2026 Jun 05. Date of Electronic Publication: 2026 Jun 05.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

NSUN2 mediates intestinal stem cell expansion and colorectal tumour initiation via MAPK/ERK signalling.

Authors: Bastem Akan A Billard CV Chen SY et al.

Source: Cell death & disease [Cell Death Dis] 2026 Mar 19; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 19.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

Synthesis, Identification, and Characterization of a Novel 1,2,5-Selenadiazole Derivative as a Microtubule Targeting Agent That Overcomes Multidrug Resistance.

Authors: Firdous F Farrukh SUB Furqan M et al.

Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2025 Sep; Vol. 358 (9), pp. e70087.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE

Loss of colonic fidelity enables multilineage plasticity and metastasis.

Authors: Cammareri P Raponi M Hong Y et al.

Source: Nature [Nature] 2025 Aug; Vol. 644 (8076), pp. 547-556. Date of Electronic Publication: 2025 Jun 04.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Genetic variation at 11q23.1 confers colorectal cancer risk by dysregulation of colonic tuft cell transcriptional activator POU2AF2.

Authors: Rajasekaran V Harris BT Osborn RT et al.

Source: Gut [Gut] 2025 Apr 07; Vol. 74 (5), pp. 787-803. Date of Electronic Publication: 2025 Apr 07.

Publication Type: Journal Article

Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE

Loss of DOCK2 potentiates Inflammatory Bowel Disease-associated colorectal cancer via immune dysfunction and IFNγ induction of IDO1 expression.

Authors: Churchhouse AMD Billard CV Suzuki T et al.

Source: Oncogene [Oncogene] 2024 Oct; Vol. 43 (42), pp. 3094-3107. Date of Electronic Publication: 2024 Sep 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer.

Authors: Hall AE Pohl SÖ Cammareri P et al.

Source: Nature communications [Nat Commun] 2022 May 19; Vol. 13 (1), pp. 2791. Date of Electronic Publication: 2022 May 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Negative regulation of TGFβ-induced apoptosis by RAC1B enhances intestinal tumourigenesis.

Authors: Gudiño V Cammareri P Billard CV et al.

Source: Cell death & disease [Cell Death Dis] 2021 Sep 25; Vol. 12 (10), pp. 873. Date of Electronic Publication: 2021 Sep 25.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

Synthesis and characterization of bis-amide SSE1917 as a microtubule-stabilizing anticancer agent.

Authors: Iqbal S Firdous F Furqan M et al.

Source: Bioorganic chemistry [Bioorg Chem] 2024 Feb; Vol. 143, pp. 107094. Date of Electronic Publication: 2024 Jan 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways.

Authors: Gudiño V Pohl SÖ Billard CV et al.

Source: Nature communications [Nat Commun] 2021 Apr 20; Vol. 12 (1), pp. 2335. Date of Electronic Publication: 2021 Apr 20.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Be like water, my cells: cell plasticity and the art of transformation.

Authors: Cammareri P Myant KB

Source: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2023 Oct 11; Vol. 11, pp. 1272730. Date of Electronic Publication: 2023 Oct 11 (Print Publication: 2023).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE

Design, Synthesis, and Biological Evaluation of SSE1806, a Microtubule Destabilizer That Overcomes Multidrug Resistance.

Authors: Firdous F Riaz S Furqan M et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2023 Sep 08; Vol. 14 (10), pp. 1369-1377. Date of Electronic Publication: 2023 Sep 08 (Print Publication: 2023).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

Alternative RNA splicing in tumour heterogeneity, plasticity and therapy.

Authors: Öther-Gee Pohl S Myant KB

Source: Disease models & mechanisms [Dis Model Mech] 2022 Jan 01; Vol. 15 (1). Date of Electronic Publication: 2022 Jan 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101483332 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1754-8411 (Electronic) Linking ISSN: 17548403 NLM ISO Abbreviation: Dis Model Mech Subsets: MEDLINE

HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.

Authors: Myant KB Cammareri P Hodder MC et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2017 Feb; Vol. 9 (2), pp. 181-197.

Publication Type: Journal Article

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1.

Authors: Dunbar K Valanciute A Lima ACS et al.

Source: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2021; Vol. 11 (2), pp. 465-489. Date of Electronic Publication: 2020 Sep 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media

Journal Info: Publisher: American Gastroenterological Association Country of Publication: United States NLM ID: 101648302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-345X (Electronic) Linking ISSN: 2352345X NLM ISO Abbreviation: Cell Mol Gastroenterol Hepatol Subsets: MEDLINE

mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.

Authors: Faller WJ Jackson TJ Knight JR et al.

Source: Nature [Nature] 2015 Jan 22; Vol. 517 (7535), pp. 497-500. Date of Electronic Publication: 2014 Nov 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo.

Authors: Phesse TJ Myant KB Cole AM et al.

Source: Cell death and differentiation [Cell Death Differ] 2014 Jun; Vol. 21 (6), pp. 956-66. Date of Electronic Publication: 2014 Feb 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE

Rac1 drives intestinal stem cell proliferation and regeneration.

Authors: Myant KB Scopelliti A Haque S et al.

Source: Cell cycle (Georgetown, Tex.) [Cell Cycle] 2013 Sep 15; Vol. 12 (18), pp. 2973-7. Date of Electronic Publication: 2013 Aug 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137841 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1551-4005 (Electronic) Linking ISSN: 15514005 NLM ISO Abbreviation: Cell Cycle Subsets: MEDLINE

A FAK-PI-3K-mTOR axis is required for Wnt-Myc driven intestinal regeneration and tumorigenesis.

Authors: Morton JP Myant KB Sansom OJ

Source: Cell cycle (Georgetown, Tex.) [Cell Cycle] 2011 Jan 15; Vol. 10 (2), pp. 173-5. Date of Electronic Publication: 2011 Jan 15.

Publication Type: Editorial

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137841 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1551-4005 (Electronic) Linking ISSN: 15514005 NLM ISO Abbreviation: Cell Cycle Subsets: MEDLINE