Search Results - "Nault, Rance"

Loss of Dioxin Response Element-Mediated Induction of PKM2 Reprograms Hepatic Metabolism in Response to TCDD.

Authors: Orlowska, Karina Nault, Rance Zacharewski, Tim

Source: International Journal of Molecular Sciences. Nov2025, Vol. 26 Issue 22, p10853. 16p.

Cell-specific AHR-driven differential gene expression in the mouse liver cell following acute TCDD exposure.

Authors: Cholico, Giovan N. Nault, Rance Zacharewski, Tim

Source: BMC Genomics. 8/28/2024, Vol. 25 Issue 1, p1-13. 13p.

Cell type- and species-specific regulation of hepatic lncRNAs by TCDD-activated aryl hydrocarbon receptor.

Authors: Post, Gavin A. Cholico, Giovan N. Nault, Rance et al.

Source: Scientific Reports. 10/24/2025, Vol. 15 Issue 1, p1-16. 16p.

Characterizing the impact of simvastatin co-treatment of cell specific TCDD-induced gene expression and systemic toxicity.

Authors: Jurgelewicz, Amanda Nault, Rance Harkema, Jack et al.

Source: Scientific Reports. 10/3/2023, Vol. 13 Issue 1, p1-12. 12p.

A Case for Accelerating Standards to Achieve the FAIR Principles of Environmental Health Research Experimental Data.

Authors: Nault, Rance Cave, Matthew C. Ludewig, Gabriele et al.

Source: Environmental Health Perspectives. Jun2023, Vol. 131 Issue 6, p065001-1-065001-8. 8p. 1 Diagram, 3 Charts, 1 Graph.

Single-cell transcriptomics shows dose-dependent disruption of hepatic zonation by TCDD in mice.

Authors: Nault, Rance Saha, Satabdi Bhattacharya, Sudin et al.

Source: Toxicological Sciences. Jan2023, Vol. 191 Issue 1, p135-148. 14p.

Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice.

Authors: Nault, Rance Fader, Kelly A. Harkema, Jack R. et al.

Source: PLoS ONE. 9/18/2017, Vol. 12 Issue 9, p1-17. 17p.

Coagulation-Driven Hepatic Fibrosis Requires Protease Activated Receptor-1 (PAR-1) in a Mouse Model of TCDD-Elicited Steatohepatitis.

Authors: Nault, Rance Fader, Kelly A. Kopec, Anna K. et al.

Source: Toxicological Sciences. Dec2016, Vol. 154 Issue 2, p381-391. 11p. 2 Diagrams, 1 Chart, 4 Graphs.

Dose-Dependent Metabolic Reprogramming and Differential Gene Expression in TCDD-Elicited Hepatic Fibrosis.

Authors: Nault, Rance Fader, Kelly A. Ammendolia, Dustin A. et al.

Source: Toxicological Sciences. Dec2016, Vol. 154 Issue 2, p253-266. 14p. 1 Color Photograph, 1 Diagram, 1 Chart, 5 Graphs.

Pyruvate Kinase Isoform Switching and Hepatic Metabolic Reprogramming by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin.

Authors: Nault, Rance Fader, Kelly A. Kirby, Mathew P. et al.

Source: Toxicological Sciences. Feb2016, Vol. 149 Issue 2, p358-371. 14p. 2 Diagrams, 6 Graphs.

2,3,7,8-Tetrachlorodibenzo-p-Dioxin Alters Lipid Metabolism and Depletes Immune Cell Populations in the Jejunum of C57BL/6 Mice.

Authors: Fader, Kelly A. Nault, Rance Ammendolia, Dustin A. et al.

Source: Toxicological Sciences. Dec2015, Vol. 148 Issue 2, p567-580. 14p. 4 Color Photographs, 2 Charts, 1 Graph.

RNA-Seq versus oligonucleotide array assessment of dose-dependent TCDDelicited hepatic gene expression in mice

Authors: Nault, Rance Fader, Kelly A Zacharewski, Tim

Source: BMC Genomics. 2015, Vol. 16 Issue 1, p373-384. 12p. 5 Graphs.

Abstracts From the 54th Annual Meeting of the Environmental Mutagenesis and Genomics Society, September 9 – 13, 2023 ‐ Chicago, IL, USA, EMGS in the Windy City: Billowing the Sails of DNA Science.

Source: Environmental & Molecular Mutagenesis. Sep2023 Supplement 1, Vol. 64, p1-135. 135p.

Genome-Wide ChIPseq Analysis of AhR, COUP-TF, and HNF4 Enrichment in TCDD-Treated Mouse Liver.

Authors: Cholico, Giovan N. Nault, Rance Zacharewski, Tim R.

Source: International Journal of Molecular Sciences. Feb2022, Vol. 23 Issue 3, p1558-N.PAG. 1p.

Consequences of reprogramming acetyl-CoA metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse liver.

Authors: Cholico, Giovan N. Orlowska, Karina Fling, Russell R. et al.

Source: Scientific Reports. 3/13/2023, Vol. 13 Issue 1, p1-14. 14p.

Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibits hepatic β-oxidation.

Authors: Cholico, Giovan N. Fling, Russell R. Zacharewski, Nicholas A. et al.

Source: Scientific Reports. 8/3/2021, Vol. 11 Issue 1, p1-20. 20p.

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Genetics-Based Approach to Identify Novel Genes Regulated by the Aryl Hydrocarbon Receptor in Mouse Liver.

Authors: Jurgelewicz, Amanda Dornbos, Peter Warren, Melanie et al.

Source: Toxicological Sciences. Jun2021, Vol. 181 Issue 2, p285-294. 10p.

Toxicogenomic Evaluation of Long-term Hepatic Effects of TCDD in Immature, Ovariectomized C57BL/6 Mice.

Authors: Kopec, Anna K. Boverhof, Darrell R. Nault, Rance et al.

Source: Toxicological Sciences. Oct2013, Vol. 135 Issue 2, p465-475. 11p. 1 Color Photograph, 1 Diagram, 3 Charts, 3 Graphs.

Acknowledgment to Reviewers of Cells in 2020.

Source: Cells (2073-4409). Feb2021, Vol. 10 Issue 2, p244. 1p.