Search Results - "Neurofibromin"

Integrative Genomic and Functional Analysis Reveals NF1 Loss as a Modifier of DNA Damage and Replication Stress Responses in Ovarian Cancer.

Authors: He S Liu C Li Z et al.

Source: Human mutation [Hum Mutat] 2026 May 18; Vol. 2026, pp. 9333284. Date of Electronic Publication: 2026 May 18 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9215429 Publication Model: eCollection Cited Medium: Internet ISSN: 1098-1004 (Electronic) Linking ISSN: 10597794 NLM ISO Abbreviation: Hum Mutat Subsets: MEDLINE

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non-NF1 patients and role of R1276.

Authors: Selig M Lohse S Elahi S et al.

Source: FEBS open bio [FEBS Open Bio] 2026 Apr; Vol. 16 (4), pp. 803-813. Date of Electronic Publication: 2025 Nov 11.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 101580716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-5463 (Electronic) Linking ISSN: 22115463 NLM ISO Abbreviation: FEBS Open Bio Subsets: MEDLINE

Metabolic and behavioral effects of neurofibromin result from differential recruitment of MAPK and mTOR signaling.

Authors: Botero V Barrios J Knauss A et al.

Source: PLoS genetics [PLoS Genet] 2026 Mar 05; Vol. 22 (3), pp. e1012061. Date of Electronic Publication: 2026 Mar 05 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient pleural mesothelioma.

Authors: Karnan S Ota A Hasan MN et al.

Source: Cell death & disease [Cell Death Dis] 2026 Feb 28; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 28.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

Personalized pharmacokinetic-pharmacodynamic guided therapy via an induced pluripotent stem cell-derived multi-organoid platform in NF1-mutant breast cancer.

Authors: Lim JH Mun SJ Kang HM et al.

Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Mar 05; Vol. 11 (1). Date of Electronic Publication: 2026 Mar 05.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE

Secondary analysis of GenRED data (Genetics of Recurrent Early-Onset major Depression) using MERLIN.

Authors: Amin M Gragnoli C

Source: European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2026 Mar; Vol. 276 (2), pp. 723-729. Date of Electronic Publication: 2025 Apr 26.

Publication Type: Journal Article

Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9103030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-8491 (Electronic) Linking ISSN: 09401334 NLM ISO Abbreviation: Eur Arch Psychiatry Clin Neurosci Subsets: MEDLINE

High Allelic Heterogeneity in Kazakhstani Patients with Neurofibromatosis Type 1: Results from the First Molecular Study.

Authors: Idrissova Z Rakhimbekova F Orazgaliyeva M et al.

Source: Genes [Genes (Basel)] 2025 Nov 19; Vol. 16 (11). Date of Electronic Publication: 2025 Nov 19.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE

NF1 and SPRED1/2 cooperate through RAS-MAPK-independent functions.

Authors: Silva JM Canche L Cheng A et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jun 02; Vol. 123 (22), pp. e2535319123. Date of Electronic Publication: 2026 May 27.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

De novo pyrimidine synthesis is a collateral metabolic vulnerability in NF2-deficient mesothelioma.

Authors: Xu D Gao Y Liu S et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2025 Sep; Vol. 17 (9), pp. 2258-2298. Date of Electronic Publication: 2025 Jul 24.

Publication Type: Journal Article

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

KMT2C Loss Promotes NF2-Wildtype Meningioma Progression and Ferroptosis Sensitivity via Epigenetic Repression of Hippo Signaling.

Authors: Zhang L Ye Y Gu W et al.

Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Apr; Vol. 13 (20), pp. e22756. Date of Electronic Publication: 2026 Feb 05.

Publication Type: Journal Article

Journal Info: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

Merlin-YAP signaling: emerging mechanisms, functions, and therapeutic approaches.

Authors: Guo P; Institute for Human Genetics and Molecular Medicine, Chinese Institutes for Medical Research (CIMR), Beijing 100069, China; Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China. Electronic address: guopengfei@cimrbj.ac.cn.

Source: Trends in cell biology [Trends Cell Biol] 2026 Apr; Vol. 36 (4), pp. 301-311. Date of Electronic Publication: 2025 Oct 21.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Publishers Country of Publication: England NLM ID: 9200566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3088 (Electronic) Linking ISSN: 09628924 NLM ISO Abbreviation: Trends Cell Biol Subsets: MEDLINE

Development of an adeno-associated virus vector for gene replacement therapy of NF1-related tumors.

Authors: Bai RY Shi J Liu J et al.

Source: Nature communications [Nat Commun] 2025 Sep 29; Vol. 16 (1), pp. 8594. Date of Electronic Publication: 2025 Sep 29.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

NF1-depleted ER⁺ breast cancers are differentially sensitive to CDK4/6 inhibitors.

Authors: Zheng ZY Chen A Jaehnig EJ et al.

Source: Science translational medicine [Sci Transl Med] 2025 Aug 27; Vol. 17 (813), pp. eadq5492. Date of Electronic Publication: 2025 Aug 27.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Pipeline to evaluate YAP-TEAD inhibitors indicates TEAD inhibition represses NF2-mutant mesothelioma.

Authors: Cunningham R Jia S Purohit K et al.

Source: Life science alliance [Life Sci Alliance] 2025 Jul 31; Vol. 8 (10). Date of Electronic Publication: 2025 Jul 31 (Print Publication: 2025).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE

NF1 mutation may be associated with lung-tropic metastasis in cutaneous melanoma: a genomic analysis of 520 patients.

Authors: Akpalamut D; Buca Seyfi Demirsoy Research and Training Hospital, Izmir, Turkey. dogancanakpalamut@gmail.com.

Source: Clinical & experimental metastasis [Clin Exp Metastasis] 2026 Jun 06; Vol. 43 (3). Date of Electronic Publication: 2026 Jun 06.

Publication Type: Journal Article

Journal Info: Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 8409970 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7276 (Electronic) Linking ISSN: 02620898 NLM ISO Abbreviation: Clin Exp Metastasis Subsets: MEDLINE

Phenotypic Spectrum of Neurofibromatosis Type 1 Patients in India and Low Prevalence of Microdeletions in NF1 Gene.

Authors: Kaur R Chowdhury MR Chauhan S et al.

Source: American journal of medical genetics. Part A [Am J Med Genet A] 2026 Jun; Vol. 200 (6), pp. 1245-1256. Date of Electronic Publication: 2026 Feb 05.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101235741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4833 (Electronic) Linking ISSN: 15524825 NLM ISO Abbreviation: Am J Med Genet A Subsets: MEDLINE

Lipidomic profile of meningiomas harboring different NF2 mutation status.

Authors: Bogusiewicz J Stanimirova I Gaca-Tabaszewska M et al.

Source: Metabolomics : Official journal of the Metabolomic Society [Metabolomics] 2026 May 07; Vol. 22 (3). Date of Electronic Publication: 2026 May 07.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101274889 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-3890 (Electronic) Linking ISSN: 15733882 NLM ISO Abbreviation: Metabolomics Subsets: MEDLINE

Genetic characterization of a Chinese cohort of suspected pediatric NF1 patients: a large-scale study using optimized whole-exome sequencing.

Authors: Wang K Jing M Mao J et al.

Source: Journal of human genetics [J Hum Genet] 2026 May; Vol. 71 (5), pp. 283-291. Date of Electronic Publication: 2025 Dec 10.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 9808008 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-232X (Electronic) Linking ISSN: 14345161 NLM ISO Abbreviation: J Hum Genet Subsets: MEDLINE

Loss of meningothelial identity and mesenchymal fate switching in NF2-mutant meningiomas.

Authors: Rahmanzade R Schweizer L Schmid S et al.

Source: Acta neuropathologica [Acta Neuropathol] 2026 Apr 25; Vol. 151 (1). Date of Electronic Publication: 2026 Apr 25.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

Malignant Phyllodes Tumor of the Breast in a Young Adult With Neurofibromatosis Type 1.

Authors: Okumura A Fujii K Kurahashi H et al.

Source: American journal of medical genetics. Part A [Am J Med Genet A] 2026 Apr; Vol. 200 (4), pp. 887-891. Date of Electronic Publication: 2025 Nov 08.

Publication Type: Case Reports; Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101235741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4833 (Electronic) Linking ISSN: 15524825 NLM ISO Abbreviation: Am J Med Genet A Subsets: MEDLINE