Search Results - "Oxindoles"

Synthesis of xanthenone fused spiro pyrrolidine oxindoles via multicomponent [3 + 2] cycloaddition reactions.

Authors: Paramasivam G Palanichamy B Paramathevar N

Source: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 6533-6542. Date of Electronic Publication: 2025 Mar 21.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Novel imidazolium salts bearing 2-oxindoles scaffold as potent acetylcholinesterase inhibitors for Alzheimer's disease: Design, synthesis, in vitro and in silico studies.

Authors: Tien LQ Phung HTT Do HH et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2026 May; Vol. 134, pp. 130560. Date of Electronic Publication: 2026 Jan 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

Rhynchophylline inhibits cluster of differentiation 36 (CD36) on endothelial cells to reduce fibrotic scar formation and enhance functional recovery after spinal cord injury.

Authors: Chopra M Singh N Verma M et al.

Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2026 Jul; Vol. 156, pp. 158219. Date of Electronic Publication: 2026 Apr 19.

Publication Type: Journal Article

Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE

Rhynchophylline as an agonist of sirtuin 3 ameliorates endothelial dysfunction via antagonizing mitochondrial damage of endothelial progenitor cells.

Authors: Lin L Sun B Hu Y et al.

Source: British journal of pharmacology [Br J Pharmacol] 2025 Aug; Vol. 182 (15), pp. 3476-3502. Date of Electronic Publication: 2025 Mar 31.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Marine-Inspired Spirooxindole PIM-1 Kinase Inhibitors Endowed with Concomitant TRKA/CDK2 Inhibition for Multifaceted Non-Small Cell Lung Cancer Apoptotic Induction.

Authors: Al-Jassas RM Islam MS Al-Majid AM et al.

Source: ChemMedChem [ChemMedChem] 2025 Jul 18; Vol. 20 (14), pp. e202500028. Date of Electronic Publication: 2025 Jun 01.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

Oxindole-Coumarin Hybrids With Broad-Spectrum Anticancer Activity: Apoptosis Induction and Selective CA IX/XII Targeting.

Authors: Abdelaal HI Mohamed AR Elnagar MR et al.

Source: Drug development research [Drug Dev Res] 2025 Jun; Vol. 86 (4), pp. e70116.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print Cited Medium: Internet ISSN: 1098-2299 (Electronic) Linking ISSN: 02724391 NLM ISO Abbreviation: Drug Dev Res Subsets: MEDLINE

Synthesis, crystal structure, Hirshfeld surface, computational and biological studies of spiro-oxindole derivatives as MDM2-p53 inhibitors.

Authors: Sivanandhan M Ragupathy S Thangamani A et al.

Source: Molecular diversity [Mol Divers] 2025 Jun; Vol. 29 (3), pp. 2157-2177. Date of Electronic Publication: 2024 Aug 29.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Oxindole derivatives alleviate paracetamol-induced nephrotoxicity and hepatotoxicity: biochemical, histological, and computational expressions.

Authors: Ahmad I Alam W Pirzada AS et al.

Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 May; Vol. 398 (5), pp. 5273-5285. Date of Electronic Publication: 2024 Nov 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

Design, Synthesis, Anti-Proliferative, and Apoptotic Assessment of Spirocyclopropyl Oxindole-Isatin Hybrids on Triple-Negative Breast Cancer.

Authors: Preeti Raza A Sharma RK et al.

Source: Chemistry & biodiversity [Chem Biodivers] 2025 May; Vol. 22 (5), pp. e202402910. Date of Electronic Publication: 2024 Dec 18.

Publication Type: Journal Article

Journal Info: Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

MC16 promotes mitochondrial biogenesis and ameliorates acute and diabetic nephropathy.

Authors: Thompson AD Hurtado KA Janda J et al.

Source: British journal of pharmacology [Br J Pharmacol] 2025 May; Vol. 182 (9), pp. 1912-1929. Date of Electronic Publication: 2025 Jan 31.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Discovery of indolinone-based covalent ULK1 inhibitors that suppressed autophagy and induced apoptosis against colorectal carcinoma.

Authors: Ye J Wang D Pang H et al.

Source: European journal of medicinal chemistry [Eur J Med Chem] 2026 Apr 05; Vol. 307, pp. 118633. Date of Electronic Publication: 2026 Jan 31.

Publication Type: Journal Article

Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Isorhyncophylline Targets PP2AC to Modulate YAP to Inhibit Endothelial Cell Inflammation.

Authors: Wang L Liu Y Li H et al.

Source: Phytotherapy research : PTR [Phytother Res] 2026 Apr; Vol. 40 (4), pp. 1793-1809. Date of Electronic Publication: 2026 Feb 02.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8904486 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1573 (Electronic) Linking ISSN: 0951418X NLM ISO Abbreviation: Phytother Res Subsets: MEDLINE

Microbial metabolite oxindole curbs acute lung injury by suppressing CXCL13.

Authors: Tang S Zhang J He Z et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Mar 03; Vol. 123 (9), pp. e2519332123. Date of Electronic Publication: 2026 Feb 27.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Synthesis, Characterization, and Evaluation of the Antifungal Properties of 3-Indolyl-3-Hydroxy Oxindole Derivatives Against Plant Pathogenic Fungi.

Authors: Bai Z Dang K Tang J et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2025 Feb 26; Vol. 30 (5). Date of Electronic Publication: 2025 Feb 26.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Discovery, bioactivities and biosynthesis of spirooxindole alkaloids.

Authors: Chen R Zhang L Zhao X et al.

Source: Natural product reports [Nat Prod Rep] 2026 Apr 29; Vol. 43 (4), pp. 650-684. Date of Electronic Publication: 2026 Apr 29.

Publication Type: Journal Article; Review

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 8502408 Publication Model: Electronic Cited Medium: Internet ISSN: 1460-4752 (Electronic) Linking ISSN: 02650568 NLM ISO Abbreviation: Nat Prod Rep Subsets: MEDLINE

Synthesis, TD-DFT calculations, molecular docking and ADME studies of new spiro-oxindole derivatives containing 5(4H)-oxazolone as anti-viral and anti-bacterial agents.

Authors: Madadi Mahani N Hamidian H Fozooni S et al.

Source: Journal of computer-aided molecular design [J Comput Aided Mol Des] 2025 Apr 11; Vol. 39 (1), pp. 14. Date of Electronic Publication: 2025 Apr 11.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 8710425 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4951 (Electronic) Linking ISSN: 0920654X NLM ISO Abbreviation: J Comput Aided Mol Des Subsets: MEDLINE

Asymmetric synthesis of spiro[4H-chromene-3,3'-oxindoles] via a squaramide-organocatalytic three-component cascade Knoevenagel/Michael/cyclization sequence.

Authors: Wang L Mu H Sun Y et al.

Source: Molecular diversity [Mol Divers] 2025 Feb; Vol. 29 (1), pp. 293-302. Date of Electronic Publication: 2024 Apr 30.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Pyrazoline Spiro-oxindole tethered 1,2,3-triazole hybrids: Design, synthesis, antimicrobial efficacy and molecular modelling studies.

Authors: Bhukal A Kumar V Raman APS et al.

Source: Molecular diversity [Mol Divers] 2025 Apr; Vol. 29 (2), pp. 1479-1492. Date of Electronic Publication: 2024 Jul 26.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Selective membrane disrupting dispiro-oxindole Dehydrocostuslactone hybrids with potent anti-MRSA, antibiofilm, and synergistic activity.

Authors: Bhushan A Rathore A Baghel VS et al.

Source: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109230. Date of Electronic Publication: 2025 Nov 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

IA-0130, a novel 3-(1,3-diarylallylidene)oxindole derivative, alleviates ovarian cancer via inhibiting IL-6/gp130/STAT3 signalling.

Authors: Park SA Kim HJ Kim LK et al.

Source: British journal of pharmacology [Br J Pharmacol] 2025 Nov; Vol. 182 (22), pp. 5670-5689. Date of Electronic Publication: 2025 Jul 28.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE