Search Results - "Perng MD"

Synergistic Effects of Glial Fibrillary Acidic Protein Mutation and Overexpression in the Pathogenesis of Alexander Disease.

Authors: Lin NH Perng MD

Source: International journal of molecular sciences [Int J Mol Sci] 2026 May 15; Vol. 27 (10). Date of Electronic Publication: 2026 May 15.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Phenotypic and molecular characterization of a recurrent SPTAN1 mutation causing SPG91.

Authors: Lan SC Perng MD Chang YY et al.

Source: Molecular biology reports [Mol Biol Rep] 2025 May 21; Vol. 52 (1), pp. 476. Date of Electronic Publication: 2025 May 21.

Publication Type: Journal Article; Case Reports

Journal Info: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE

Experimental Approaches for Biochemical Analysis of Glial Fibrillary Acidic Protein and Its Disease-associated Variants.

Authors: Lin NH Perng MD

Source: Journal of visualized experiments : JoVE [J Vis Exp] 2025 Nov 28 (225). Date of Electronic Publication: 2025 Nov 28.

Publication Type: Journal Article; Video-Audio Media; Research Support, Non-U.S. Gov't

Journal Info: Publisher: MYJoVE Corporation Country of Publication: United States NLM ID: 101313252 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-087X (Electronic) Linking ISSN: 1940087X NLM ISO Abbreviation: J Vis Exp Subsets: MEDLINE

Deletions in Glial Fibrillary Acidic Protein Leading to Alterations in Intermediate Filament Assembly and Network Formation.

Authors: Lin NH Jian WS Perng MD

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Feb 23; Vol. 26 (5). Date of Electronic Publication: 2025 Feb 23.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

The Relationship between Obesity-Related Factors and Graves' Orbitopathy: A Pilot Study.

Authors: Lu C Lai CL Yang CM et al.

Source: Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2022 Nov 29; Vol. 58 (12). Date of Electronic Publication: 2022 Nov 29.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Electronic Cited Medium: Internet ISSN: 1648-9144 (Electronic) Linking ISSN: 1010660X NLM ISO Abbreviation: Medicina (Kaunas) Subsets: MEDLINE

Type II Alexander disease caused by splicing errors and aberrant overexpression of an uncharacterized GFAP isoform.

Authors: Helman G Takanohashi A Hagemann TL et al.

Source: Human mutation [Hum Mutat] 2022 Sep; Vol. 43 (9), pp. 1344.

Publication Type: Published Erratum

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9215429 Publication Model: Print Cited Medium: Internet ISSN: 1098-1004 (Electronic) Linking ISSN: 10597794 NLM ISO Abbreviation: Hum Mutat Subsets: PubMed not MEDLINE

Development of Fusion-Based Assay as a Drug Screening Platform for Nipah Virus Utilizing Baculovirus Expression Vector System.

Authors: Sari IP Ortiz CLD Yang LW et al.

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 22; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 22.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Glial fibrillary acidic protein is pathologically modified in Alexander disease.

Authors: Lin NH Jian WS Snider N et al.

Source: The Journal of biological chemistry [J Biol Chem] 2024 Jul; Vol. 300 (7), pp. 107402. Date of Electronic Publication: 2024 May 21.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Antisense therapy in a rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment.

Authors: Hagemann TL Powers B Lin NH et al.

Source: Science translational medicine [Sci Transl Med] 2021 Nov 17; Vol. 13 (620), pp. eabg4711. Date of Electronic Publication: 2021 Nov 17.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Elevated GFAP isoform expression promotes protein aggregation and compromises astrocyte function.

Authors: Lin NH Yang AW Chang CH et al.

Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 May; Vol. 35 (5), pp. e21614.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

Recessively-Inherited Adult-Onset Alexander Disease Caused by a Homozygous Mutation in the GFAP Gene.

Authors: Fu MH Chang YY Lin NH et al.

Source: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2020 Sep; Vol. 35 (9), pp. 1662-1667. Date of Electronic Publication: 2020 May 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8610688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8257 (Electronic) Linking ISSN: 08853185 NLM ISO Abbreviation: Mov Disord Subsets: MEDLINE

Type II Alexander disease caused by splicing errors and aberrant overexpression of an uncharacterized GFAP isoform.

Authors: Helman G Takanohashi A Hagemann TL et al.

Source: Human mutation [Hum Mutat] 2020 Jun; Vol. 41 (6), pp. 1131-1137. Date of Electronic Publication: 2020 Mar 11.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9215429 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1004 (Electronic) Linking ISSN: 10597794 NLM ISO Abbreviation: Hum Mutat Subsets: MEDLINE

Chlorella sorokiniana Extract Prevents Cisplatin-Induced Myelotoxicity In Vitro and In Vivo.

Authors: Lin SH Li MH Chuang KA et al.

Source: Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2020 Jan 25; Vol. 2020, pp. 7353618. Date of Electronic Publication: 2020 Jan 25 (Print Publication: 2020).

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101479826 Publication Model: eCollection Cited Medium: Internet ISSN: 1942-0994 (Electronic) Linking ISSN: 19420994 NLM ISO Abbreviation: Oxid Med Cell Longev Subsets: MEDLINE

Site-specific phosphorylation and caspase cleavage of GFAP are new markers of Alexander disease severity.

Authors: Battaglia RA Beltran AS Delic S et al.

Source: ELife [Elife] 2019 Nov 04; Vol. 8. Date of Electronic Publication: 2019 Nov 04.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo.

Authors: Lin NH Goh A Lin SH et al.

Source: Journal of Alzheimer's disease reports [J Alzheimers Dis Rep] 2023 Jan 27; Vol. 7 (1), pp. 51-76. Date of Electronic Publication: 2023 Jan 27 (Print Publication: 2023).

Publication Type: Journal Article

Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 101705500 Publication Model: eCollection Cited Medium: Internet ISSN: 2542-4823 (Electronic) Linking ISSN: 25424823 NLM ISO Abbreviation: J Alzheimers Dis Rep Subsets: PubMed not MEDLINE

Effects of Alexander disease-associated mutations on the assembly and organization of GFAP intermediate filaments.

Authors: Yang AW Lin NH Yeh TH et al.

Source: Molecular biology of the cell [Mol Biol Cell] 2022 Jul 01; Vol. 33 (8), pp. ar69. Date of Electronic Publication: 2022 May 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Cell Biology Country of Publication: United States NLM ID: 9201390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-4586 (Electronic) Linking ISSN: 10591524 NLM ISO Abbreviation: Mol Biol Cell Subsets: MEDLINE

Aggregation-prone GFAP mutation in Alexander disease validated using a zebrafish model.

Authors: Lee SH Nam TS Kim KH et al.

Source: BMC neurology [BMC Neurol] 2017 Sep 07; Vol. 17 (1), pp. 175. Date of Electronic Publication: 2017 Sep 07.

Publication Type: Case Reports; Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968555 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2377 (Electronic) Linking ISSN: 14712377 NLM ISO Abbreviation: BMC Neurol Subsets: MEDLINE

Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP.

Authors: Lin NH Messing A Perng MD

Source: PloS one [PLoS One] 2017 Jul 10; Vol. 12 (7), pp. e0180694. Date of Electronic Publication: 2017 Jul 10 (Print Publication: 2017).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

A novel in-frame GFAP p.E138_L148del mutation in Type II Alexander disease with atypical phenotypes.

Authors: Kang YR Lee SH Lin NH et al.

Source: European journal of human genetics : EJHG [Eur J Hum Genet] 2022 Jun; Vol. 30 (6), pp. 687-694. Date of Electronic Publication: 2022 Mar 04.

Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9302235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5438 (Electronic) Linking ISSN: 10184813 NLM ISO Abbreviation: Eur J Hum Genet Subsets: MEDLINE

Rhinacanthin C Alleviates Amyloid-β Fibrils' Toxicity on Neurons and Attenuates Neuroinflammation Triggered by LPS, Amyloid-β, and Interferon-γ in Glial Cells.

Authors: Chuang KA Li MH Lin NH et al.

Source: Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2017; Vol. 2017, pp. 5414297. Date of Electronic Publication: 2017 Oct 18.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101479826 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0994 (Electronic) Linking ISSN: 19420994 NLM ISO Abbreviation: Oxid Med Cell Longev Subsets: MEDLINE