Search Results - "Prions"

Distinct prion conformers from brain and peripheral tissues of gene-targeted mice produce convergent CWD strain properties.

Authors: DeFranco JP Atkinson ZN Crowell J et al.

Source: PLoS pathogens [PLoS Pathog] 2026 Jun 04; Vol. 22 (6), pp. e1014303. Date of Electronic Publication: 2026 Jun 04 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

PrP turnover in vivo and the time to effect of prion disease therapeutics.

Authors: Corridon TL O'Moore J Seerley A et al.

Source: PLoS pathogens [PLoS Pathog] 2026 May 26; Vol. 22 (5), pp. e1014263. Date of Electronic Publication: 2026 May 26 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

A Neuronal Cell Line Model for Studying Camel Prions.

Authors: Abdulrahman B Rahimi Aqdam S Mosca M et al.

Source: Pathogens (Basel, Switzerland) [Pathogens] 2026 Apr 27; Vol. 15 (5). Date of Electronic Publication: 2026 Apr 27.

Publication Type: Journal Article

Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101596317 Publication Model: Electronic Cited Medium: Internet ISSN: 2076-0817 (Electronic) Linking ISSN: 20760817 NLM ISO Abbreviation: Pathogens Subsets: MEDLINE

Prion shedding is reduced by chronic wasting disease vaccination.

Authors: Ahmed-Hassan H Abdelaziz D Cheng YC et al.

Source: PLoS pathogens [PLoS Pathog] 2026 Apr 24; Vol. 22 (4), pp. e1014166. Date of Electronic Publication: 2026 Apr 24 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Prion propagation is controlled by a hierarchical network involving the nuclear Tfap2c and hnRNP K factors and the cytosolic mTORC1 complex.

Authors: Sellitto S Caredio D Bimbati M et al.

Source: PLoS pathogens [PLoS Pathog] 2026 Apr 20; Vol. 22 (4), pp. e1014056. Date of Electronic Publication: 2026 Apr 20 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Chemo-omic pipeline enables discovery of prion synaptotoxic pathways and inhibitory drugs.

Authors: Le NTT Mercer RCC Fang C et al.

Source: PLoS pathogens [PLoS Pathog] 2026 Jun 18; Vol. 22 (6), pp. e1014314. Date of Electronic Publication: 2026 Jun 18 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Hyperglycemia impairs cognitive function by inducing mitochondrial damage through lactylation of LRPPRC at K223.

Authors: Xu J Hao Y Cao J et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2026 Jun; Vol. 18 (6), pp. 2038-2061. Date of Electronic Publication: 2026 Apr 06.

Publication Type: Journal Article

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

Divalent siRNA for prion disease.

Authors: Gentile JE Corridon TL Serack FE et al.

Source: Nucleic acids research [Nucleic Acids Res] 2026 Apr 23; Vol. 54 (8).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains.

Authors: Eraña H Vidal E Fernández-Borges N et al.

Source: Brain pathology (Zurich, Switzerland) [Brain Pathol] 2026 Jul; Vol. 36 (4), pp. e70083. Date of Electronic Publication: 2026 Feb 09.

Publication Type: Journal Article

Journal Info: Publisher: International Society of Neuropathology Country of Publication: Switzerland NLM ID: 9216781 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-3639 (Electronic) Linking ISSN: 10156305 NLM ISO Abbreviation: Brain Pathol Subsets: MEDLINE

Rapid generation of prion disease models using AAV-delivered PrP variants in knockout mice.

Authors: San-Juan-Ansoleaga M Fernández-Muñoz E Charco JM et al.

Source: Brain pathology (Zurich, Switzerland) [Brain Pathol] 2026 Jul; Vol. 36 (4), pp. e70077. Date of Electronic Publication: 2026 Jan 31.

Publication Type: Journal Article

Journal Info: Publisher: International Society of Neuropathology Country of Publication: Switzerland NLM ID: 9216781 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-3639 (Electronic) Linking ISSN: 10156305 NLM ISO Abbreviation: Brain Pathol Subsets: MEDLINE

Practical Real-Time Quaking-Induced Conversion for Detecting Classical Bovine Spongiform Encephalopathy and Classical and Atypical Scrapie Prions.

Authors: Suzuki A Sawada K Nakashima T et al.

Source: Pathogens (Basel, Switzerland) [Pathogens] 2026 Mar 20; Vol. 15 (3). Date of Electronic Publication: 2026 Mar 20.

Publication Type: Journal Article

Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101596317 Publication Model: Electronic Cited Medium: Internet ISSN: 2076-0817 (Electronic) Linking ISSN: 20760817 NLM ISO Abbreviation: Pathogens Subsets: MEDLINE

A phase separation hypothesis for the biological function of PrP: the role of multivalent interactions at the plasma membrane.

Authors: Freire MH Linden R Cordeiro Y

Source: Biochemical Society transactions [Biochem Soc Trans] 2026 Jan 28; Vol. 54 (1), pp. 83-93.

Publication Type: Journal Article; Review

Journal Info: Publisher: Portland Press On The Behalf Of The Biochemical Society Country of Publication: England NLM ID: 7506897 Publication Model: Print Cited Medium: Internet ISSN: 1470-8752 (Electronic) Linking ISSN: 03005127 NLM ISO Abbreviation: Biochem Soc Trans Subsets: MEDLINE

Silent Propagation of Classical Scrapie Prions in Homozygous K222 Transgenic Mice.

Authors: Fernández-Borges N Marín-Moreno A Espinosa JC et al.

Source: Emerging infectious diseases [Emerg Infect Dis] 2025 Dec; Vol. 31 (12), pp. 2254-2264.

Publication Type: Journal Article

Journal Info: Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE

Chronic wasting disease as a model for human prion therapy.

Authors: Bordonaro M; Department of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA, USA.

Source: Prion [Prion] 2025 Dec; Vol. 19 (1), pp. 17-22. Date of Electronic Publication: 2025 May 24.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101472305 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-690X (Electronic) Linking ISSN: 19336896 NLM ISO Abbreviation: Prion Subsets: MEDLINE

Prion 2024 conference: from two decades of growth to a new journey forward.

Authors: Kong Y Huang P Shi Q et al.

Source: Prion [Prion] 2025 Dec; Vol. 19 (1), pp. 1-7. Date of Electronic Publication: 2025 Jun 03.

Publication Type: Conference Proceedings; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101472305 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-690X (Electronic) Linking ISSN: 19336896 NLM ISO Abbreviation: Prion Subsets: MEDLINE

Substitution of histidine 95 by tyrosine in the prion protein causes spontaneous neurodegeneration in transgenic mice.

Authors: Torres JM Marín-Moreno A Espinosa JC et al.

Source: PLoS pathogens [PLoS Pathog] 2025 Oct 16; Vol. 21 (10), pp. e1013554. Date of Electronic Publication: 2025 Oct 16 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Contrasting roles of autophagy in cellular prion infection.

Authors: Abdulrahman B Heiseke A Aguib Y et al.

Source: Autophagy [Autophagy] 2025 Dec; Vol. 21 (12), pp. 3361-3379. Date of Electronic Publication: 2025 Aug 13.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE

Detection of chronic wasting disease prions in soil at an illegal white-tailed deer carcass disposal site.

Authors: Grunklee MK Lichtenberg SS Lurndahl NA et al.

Source: Prion [Prion] 2025 Dec; Vol. 19 (1), pp. 8-19. Date of Electronic Publication: 2025 Jun 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101472305 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-690X (Electronic) Linking ISSN: 19336896 NLM ISO Abbreviation: Prion Subsets: MEDLINE

Beyond prion-like spreading in neurodegenerative disease.

Authors: Meisl G Rowe JB Klenerman D

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Oct; Vol. 21 (10), pp. e70789.

Publication Type: Journal Article; Review

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

Strain-specific propagation of variant Creutzfeldt-Jakob disease prions in humanized neural cells.

Authors: Rayner MLD Arora P Linehan JM et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jun 16; Vol. 123 (24), pp. e2609054123. Date of Electronic Publication: 2026 Jun 11.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE