Search Results - "Protein stability"

Prediction of protein biophysical traits from limited data: a case study on nanobody thermostability through NanoMelt.

Authors: Ramon A Ni M Predeina O et al.

Source: MAbs [MAbs] 2025 Dec; Vol. 17 (1), pp. 2442750. Date of Electronic Publication: 2025 Jan 08.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE

dUTPase is essential in zebrafish development and possesses several single-nucleotide variants with pronounced structural and functional consequences.

Authors: Perey-Simon V Békesi A Kazzazy L et al.

Source: FEBS open bio [FEBS Open Bio] 2026 Jun; Vol. 16 (6), pp. 1087-1101. Date of Electronic Publication: 2025 Dec 16.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 101580716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-5463 (Electronic) Linking ISSN: 22115463 NLM ISO Abbreviation: FEBS Open Bio Subsets: MEDLINE

Comparative unfolding of the Trp-cage miniprotein in anionic and cationic surfactants.

Authors: Nnyigide OS Byeon H Okpete UE

Source: PloS one [PLoS One] 2026 Jun 03; Vol. 21 (6), pp. e0347734. Date of Electronic Publication: 2026 Jun 03 (Print Publication: 2026).

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

ROWVA: A Structure-Based Metric for Predicting the Pathogenicity of Protein Variants Using Alphafold2.

Authors: Furutani T Okusha Y Nagami H et al.

Source: Cancer science [Cancer Sci] 2026 Jun; Vol. 117 (6), pp. 1736-1747. Date of Electronic Publication: 2026 Apr 07.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE

K294E change in the rotavirus factory forming protein NSP2 stabilizes a rare C-terminal conformation.

Authors: Nichols SL Hollis T Salsbury FR et al.

Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2026 Jun; Vol. 44 (9), pp. 4422-4438. Date of Electronic Publication: 2025 Sep 26.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

Computational prioritization of deleterious human myelin protein zero gene mutations reveals structural disruption and potential myelin dysfunction through dynamic simulations and stability analysis.

Authors: Alhassan HH Surti M Patel M

Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2026 Jun; Vol. 44 (9), pp. 4439-4458. Date of Electronic Publication: 2025 Oct 03.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

Identification of deleterious missense variants of serine peptidase inhibitor Kazal type 2 gene and their impact on KAZAL domain structure, stability, flexibility, and dimension.

Authors: Elkarhat G Ait Benichou S Redouane S et al.

Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2026 Jun; Vol. 44 (9), pp. 4642-4653. Date of Electronic Publication: 2026 Jan 30.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

Mutations in the Txnip PPXY motifs protect against myocardial infarction despite enhanced protein stability.

Authors: Nakayama Y Kitaura A Abdali SA et al.

Source: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2026 Jun 01; Vol. 330 (6), pp. H1732-H1748. Date of Electronic Publication: 2026 Apr 22.

Publication Type: Journal Article

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1539 (Electronic) Linking ISSN: 03636135 NLM ISO Abbreviation: Am J Physiol Heart Circ Physiol Subsets: MEDLINE

LsMAPK6 Phosphorylates the LsCO Protein to Enhance Its Stability and Transcriptional Activity, Promoting Floral Transition Upon High Temperatures in Lettuce.

Authors: Wang T Liu M Tian Y et al.

Source: Plant biotechnology journal [Plant Biotechnol J] 2026 Jun; Vol. 24 (6), pp. 4064-4083. Date of Electronic Publication: 2026 Mar 07.

Publication Type: Journal Article

Journal Info: Publisher: Wiley on behalf of the Society for Experimental Biology, Association of Applied Biologists Country of Publication: England NLM ID: 101201889 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-7652 (Electronic) Linking ISSN: 14677644 NLM ISO Abbreviation: Plant Biotechnol J Subsets: MEDLINE

Computational study of deleterious missense SNPs in the USH1G gene implicated in Usher syndrome.

Authors: El Khair K Toure M Redouane S et al.

Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2026 Jun; Vol. 44 (9), pp. 4388-4405. Date of Electronic Publication: 2025 Sep 02.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

Exploring the functional and structural impacts of high-risk nsSNPs in human BMP15 and GDF9 genes associated with premature ovarian failure: an in silico approach.

Authors: Navapour L Jamali Z Ghasemnejad-Berenji H et al.

Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2026 Jun; Vol. 44 (9), pp. 4369-4387. Date of Electronic Publication: 2025 Aug 26.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

RILPL2 suppresses metabolic reprogramming and progression of cervical cancer by attenuating LDHA protein stability and inhibiting H3K18 lactylation.

Authors: Shi Y Zhang Z Liu J et al.

Source: Cell death & disease [Cell Death Dis] 2026 May 04; Vol. 17 (1). Date of Electronic Publication: 2026 May 04.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

MuFaDDG: a sequence-based multiscale feature fusion framework for protein stability changes prediction.

Authors: Gong J Ma P Ren Z et al.

Source: Bioinformatics (Oxford, England) [Bioinformatics] 2026 May 03; Vol. 42 (5).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9808944 Publication Model: Print Cited Medium: Internet ISSN: 1367-4811 (Electronic) Linking ISSN: 13674803 NLM ISO Abbreviation: Bioinformatics Subsets: MEDLINE

Subtype-dependent PD-L1 stability and immune context shape immunotherapy response in hepatocellular carcinoma.

Authors: Grisetti L Garcia CJC Tarchi P et al.

Source: Frontiers in immunology [Front Immunol] 2026 May 01; Vol. 17, pp. 1822947. Date of Electronic Publication: 2026 May 01 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Environmental and mutational modulation of collateral fitness effects informs their mechanisms.

Authors: Goff C Tsou EY Mehlhoff JD et al.

Source: Molecular biology and evolution [Mol Biol Evol] 2026 May 01; Vol. 43 (5).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 8501455 Publication Model: Print Cited Medium: Internet ISSN: 1537-1719 (Electronic) Linking ISSN: 07374038 NLM ISO Abbreviation: Mol Biol Evol Subsets: MEDLINE

Biophysical, sequence and structural analysis of type 3 secretion system pilus protein HrpA of Pseudomonas syringae: insights into HrpA pili stability and assembly.

Authors: Arasakumar N Loganathan V Natesh R et al.

Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2026 May; Vol. 44 (8), pp. 3833-3851. Date of Electronic Publication: 2025 Aug 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

GTPase Rab11b and effector Rab11-FIP2 promote NLRP3 stability during inflammasome priming.

Authors: Gravastrand CS Yurchenko M Kristensen S et al.

Source: The EMBO journal [EMBO J] 2026 May; Vol. 45 (9), pp. 2991-3021. Date of Electronic Publication: 2026 Mar 25.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

Genomic and structural analysis of the endocannabinoid system in Moroccans: A novel CNR1 variant (V392A) impairs CB1 receptor stability.

Authors: Abbou H Festali R Chemao-Elfihri MW et al.

Source: PloS one [PLoS One] 2026 Apr 30; Vol. 21 (4), pp. e0347606. Date of Electronic Publication: 2026 Apr 30 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Wnt-dependent Frizzled clustering is required for Dishevelled phosphorylation but insufficient for β-catenin stabilization.

Authors: Moldaver S Thibeault PE Robitaille M et al.

Source: Science signaling [Sci Signal] 2026 Apr 07; Vol. 19 (932), pp. eaec0204. Date of Electronic Publication: 2026 Apr 07.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

Transforming a fragile protein helix into an ultrastable scaffold via a hierarchical AI and chemistry framework.

Authors: Qiu J Tang G Feng T et al.

Source: ELife [Elife] 2026 Apr 02; Vol. 15. Date of Electronic Publication: 2026 Apr 02.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE