Search Results - "Rankovic Z"

Safety considerations for cereblon-recruiting targeted protein degraders.

Authors: Garside H Aslamkhan A Daniels DL et al.

Source: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2026 Apr 20. Date of Electronic Publication: 2026 Apr 20.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124171 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-1784 (Electronic) Linking ISSN: 14741776 NLM ISO Abbreviation: Nat Rev Drug Discov Subsets: MEDLINE

Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics.

Authors: Steger M Nishiguchi G Wu Q et al.

Source: Nature communications [Nat Commun] 2025 Aug 20; Vol. 16 (1), pp. 7773. Date of Electronic Publication: 2025 Aug 20.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemia.

Authors: Yoshimura S Actis M Seffernick JT et al.

Source: Blood [Blood] 2026 Mar 12. Date of Electronic Publication: 2026 Mar 12.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy.

Authors: Zuckermann M He C Andrews J et al.

Source: Molecular cancer [Mol Cancer] 2024 Jun 07; Vol. 23 (1), pp. 123. Date of Electronic Publication: 2024 Jun 07.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE

LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemia.

Authors: Yang JJ Nishiguchi G Yoshimura S et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jul 07. Date of Electronic Publication: 2025 Jul 07.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines.

Authors: Nishiguchi G Mascibroda LG Young SM et al.

Source: Nature communications [Nat Commun] 2024 Jan 16; Vol. 15 (1), pp. 482. Date of Electronic Publication: 2024 Jan 16.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

ATM inhibition enhances the efficacy of radiation across distinct molecular subgroups of pediatric high-grade glioma.

Authors: Xie J Kuriakose T Bianski B et al.

Source: Neuro-oncology [Neuro Oncol] 2023 Oct 03; Vol. 25 (10), pp. 1828-1841.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE

Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target.

Authors: Ahmad ST Li Y Garcia-Lopez J et al.

Source: Cancer cell [Cancer Cell] 2025 Jun 09; Vol. 43 (6), pp. 1141-1158.e11. Date of Electronic Publication: 2025 May 15.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

HTS Identifies NUP98-KDM5A-PHD3 Domain Ligands with Novel Scaffolds.

Authors: Lin W Slavish PJ Phillips AH et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2025 May 05; Vol. 16 (6), pp. 1080-1088. Date of Electronic Publication: 2025 May 05 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

Evaluation of Cereblon-Directing Warheads for the Development of Orally Bioavailable PROTACs.

Authors: Actis M Cresser-Brown J Caine EA et al.

Source: Journal of medicinal chemistry [J Med Chem] 2025 Feb 13; Vol. 68 (3), pp. 3591-3611. Date of Electronic Publication: 2025 Jan 15.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Continuous collective analysis of chemical reactions.

Authors: Hu M Yang L Twarog N et al.

Source: Nature [Nature] 2024 Dec; Vol. 636 (8042), pp. 374-379. Date of Electronic Publication: 2024 Dec 11.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE; PubMed not MEDLINE

Preclinical evaluation of proteolytic targeting of LCK as a therapeutic approach in T cell acute lymphoblastic leukemia.

Authors: Hu J Jarusiewicz J Du G et al.

Source: Science translational medicine [Sci Transl Med] 2022 Aug 24; Vol. 14 (659), pp. eabo5228. Date of Electronic Publication: 2022 Aug 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma.

Authors: Singh S Abu-Zaid A Jin H et al.

Source: Science translational medicine [Sci Transl Med] 2022 Jul 13; Vol. 14 (653), pp. eabq2096. Date of Electronic Publication: 2022 Jul 13.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Structure-Activity Relationship of Potent, Selective, and Orally Bioavailable Molecular Glue Degraders of CK1α.

Authors: Nishiguchi G Caine EA McGowan K et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2024 Sep 12; Vol. 15 (10), pp. 1692-1698. Date of Electronic Publication: 2024 Sep 12 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

Sonic Hedgehog activates prostaglandin signaling to stabilize primary cilium length.

Authors: Ansari SS Dillard ME Zhang Y et al.

Source: The Journal of cell biology [J Cell Biol] 2024 Sep 02; Vol. 223 (9). Date of Electronic Publication: 2024 Jun 10.

Publication Type: Journal Article

Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8140 (Electronic) Linking ISSN: 00219525 NLM ISO Abbreviation: J Cell Biol Subsets: MEDLINE

Development of an Orally Bioavailable LCK PROTAC Degrader as a Potential Therapeutic Approach to T-Cell Acute Lymphoblastic Leukemia.

Authors: Jarusiewicz JA Yoshimura S Actis M et al.

Source: Journal of medicinal chemistry [J Med Chem] 2024 Jul 25; Vol. 67 (14), pp. 11868-11884. Date of Electronic Publication: 2024 Jul 08.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.

Authors: He C Xu K Zhu X et al.

Source: Nature communications [Nat Commun] 2021 Jul 02; Vol. 12 (1), pp. 4089. Date of Electronic Publication: 2021 Jul 02.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma.

Authors: Abu-Zaid A Fang J Jin H et al.

Source: Cell reports. Medicine [Cell Rep Med] 2024 Mar 19; Vol. 5 (3), pp. 101468.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE

A high-throughput quality control method for assessing the serial dilution performance of dose-response plates with acoustic ejection mass spectrometry.

Authors: Rimmer MA Twarog NR Li Y et al.

Source: SLAS technology [SLAS Technol] 2024 Feb; Vol. 29 (1), pp. 100115. Date of Electronic Publication: 2023 Nov 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101697564 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2472-6311 (Electronic) Linking ISSN: 24726303 NLM ISO Abbreviation: SLAS Technol Subsets: MEDLINE

Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.

Authors: Yang SW Huang X Lin W et al.

Source: Nature communications [Nat Commun] 2020 Oct 01; Vol. 11 (1), pp. 4931. Date of Electronic Publication: 2020 Oct 01.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE