Search Results - "Roth, Bryan"

Nanobody-drug conjugates for targeting specific GPCR pairs.

Authors: Huang, Xianglin Roth, Bryan L.

Source: PLoS Biology. 11/21/2025, Vol. 23 Issue 11, p1-4. 4p.

Corrigendum: The promise and peril of chemical probes.

Authors: Arrowsmith, Cheryl H Audia, James E Austin, Christopher et al.

Source: Nature Chemical Biology. Nov2015, Vol. 11 Issue 11, p887-887. 1p.

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Structural biology: Serotonin signalling secrets.

Source: Nature. 3/28/2013, Vol. 495 Issue 7442, p412-413. 2p.

Subjects: Serotonin receptors, Crystal structure, Roth, Bryan

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Advancing drug discovery for schizophrenia.

Authors: Marder, Stephen R. Roth, Bryan Sullivan, Patrick F. et al.

Source: Annals of the New York Academy of Sciences. Oct2011, Vol. 1236 Issue 1, p30-43. 14p.

Integrated omics revealed the altered colonic microenvironment after inhibition of peripheral serotonin synthesis by LP533401.

Authors: Ling, Yidan Liu, Ziyu Han, Shuibing et al.

Source: iMetaOmics. Dec2024, Vol. 1 Issue 2, p1-18. 18p.

The activities of drug inactive ingredients on biological targets.

Authors: Pottel, Joshua Armstrong, Duncan Ling Zou et al.

Source: Science (pre-March 2025). 7/24/2020, Vol. 369 Issue 6502, p403-413. 11p. 1 Color Photograph, 4 Diagrams, 1 Chart.

The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor.

Authors: Roth, Bryan L. Gibbons, Simon Arunotayanun, Warunya et al.

Source: PLoS ONE. Mar2013, Vol. 8 Issue 3, p1-5. 5p.

Involvement of AMPA receptor phosphorylation in antidepressant actions with special reference to tianeptine.

Authors: Svenningsson, Per Bateup, Helen Qi, Hongshi et al.

Source: European Journal of Neuroscience. Dec2007, Vol. 26 Issue 12, p3509-3517. 9p. 1 Chart, 5 Graphs.

Subjects: Mental depression, Glutamic acid, Cellular signal transduction, Neuroplasticity, Laboratory mice, Neurosciences

Retrieving Data from Crystal Structures of Homoleptic Complexes: Secondary Building Units.

Authors: Shevchenko, A. P. Pershin, A. A. Morkhova, E. A.

Source: Journal of Structural Chemistry. Jun2025, Vol. 66 Issue 6, p1122-1146. 25p.

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The role of modern neuroscience in the renaissance of psychedelic research.

Alternate Title: El rol de la neurociencia moderna en el renacimiento de la investigación psicodélica.

Authors: Evans, Kathryn E. Massengill, Crystian Alvarado, Jonnathan Singh

Source: Costa Rican Journal of Psychology / Revista Costarricense de Psicología. Jan-Jun2025, Vol. 44 Issue 1, p1-23. 23p.

Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo.

Authors: Abbas, Atheir I. Hedlund, Peter B. Xi-Ping Huang et al.

Source: Psychopharmacology. Jul2009, Vol. 205 Issue 1, p119-128.

WAY-100635 is a potent dopamine D4 receptor agonist.

Authors: Chemel, Benjamin R. Roth, Bryan L. Armbruster, Blaine et al.

Source: Psychopharmacology. Oct2006, Vol. 188 Issue 2, p244-251.

The highly efficacious actions ofN-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: is M1 agonism a pre-requisite for mimicking clozapine’s actions?

Authors: Davies, Marilyn A. Compton-Toth, Beth Ann Hufeisen, Sandra J. et al.

Source: Psychopharmacology. Apr2005, Vol. 178 Issue 4, p451-460.

Serotonin receptors represent highly favorable molecular targets for cognitive enhancement in schizophrenia and other disorders.

Authors: Roth, Bryan L. Hanizavareh, S. Mohammad Blum, Andrew E.

Source: Psychopharmacology. 2004, Vol. 174 Issue 1, p17-24.

The in vitro pharmacology of the β-adrenergic receptor pet ligand (s)-fluorocarazolol reveals high affinity for cloned β-adrenergic receptors and moderate affinity for the human 5-HT[sub 1A] receptor.

Authors: Roth, Bryan L. Ernsberger, Paul Steinberg, Se Anna et al.

Source: Psychopharmacology. 2001, Vol. 157 Issue 1, p111.

Community guidelines for GPCR ligand bias: IUPHAR review 32.

Authors: Kolb, Peter Kenakin, Terry Alexander, Stephen P. H. et al.

Source: British Journal of Pharmacology. Jul2022, Vol. 179 Issue 14, p3651-3674. 24p. 2 Diagrams, 4 Charts, 1 Graph.

Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.

Authors: Huang, Xi-Ping Karpiak, Joel Kroeze, Wesley K. et al.

Source: Nature. 11/26/2015, Vol. 527 Issue 7579, p477-483. 7p. 1 Diagram, 15 Graphs.

Subjects: Allosteric proteins, G protein coupled receptors, Ligands (Biochemistry), Benzodiazepines, Lorazepam, Genetics