Search Results - "Tainer JA"

EEPD1 evolved a unique DNA clamping dimer protecting reversed replication forks.

Authors: Shen R Sarker AH Chen Y et al.

Source: Nucleic acids research [Nucleic Acids Res] 2026 Feb 24; Vol. 54 (5).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

PARG Governs a PARylation-Ubiquitination Toggle that Stabilizes RAD51AP1 to Drive Homologous Recombination-Mediated Chemoresistance.

Authors: He H Hu Y Lu Y et al.

Source: Cancer research [Cancer Res] 2026 Jun 18. Date of Electronic Publication: 2026 Jun 18.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

DPY30 Is an Epigenetic Decoupler Linking Replication Stress to Immunoediting in Pancreatic Cancer.

Authors: Citron F Cecchetto L Granato E et al.

Source: Cancer research [Cancer Res] 2026 Jun 15; Vol. 86 (12), pp. 2837-2859.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Orchestrated metal ion repositioning defines the dynamic catalytic strategy of the essential DNA repair nuclease APE1.

Authors: Serafim LF Tsutakawa SE Arvai AS et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 14. Date of Electronic Publication: 2026 May 14.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Characteristics and Clinical Outcomes of BRCA Germline Mutation Carriers with Advanced Breast Cancer Treated with PARP (Poly ADP-Ribose Polymerase) Inhibitors: A Single-Institution Experience.

Authors: Akkoc Mustafayev FN Fountzilas E Munsell MF et al.

Source: Cancers [Cancers (Basel)] 2026 Apr 16; Vol. 18 (8). Date of Electronic Publication: 2026 Apr 16.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE

RNA/DNA-binding protein TDP43 regulates DNA mismatch repair genes with implications for genome stability.

Authors: Provasek VE Bacolla A Rangaswamy S et al.

Source: Nucleic acids research [Nucleic Acids Res] 2025 Sep 23; Vol. 53 (18).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Poly(ADP-ribose) glycohydrolase enforces p21 degradation via dePARylation to promote gastric cancer progression.

Authors: Hu Y Bao Q Huang Y et al.

Source: The Journal of clinical investigation [J Clin Invest] 2026 Jan 15; Vol. 136 (5). Date of Electronic Publication: 2026 Jan 15 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

Molecular model of TFIIH recruitment to the transcription-coupled repair machinery.

Authors: Paul T Yan C Yu J et al.

Source: Nature communications [Nat Commun] 2025 Mar 08; Vol. 16 (1), pp. 2341. Date of Electronic Publication: 2025 Mar 08.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism.

Authors: Brosey CA Shen R Tainer JA

Source: The EMBO journal [EMBO J] 2025 Feb; Vol. 44 (4), pp. 1220-1248. Date of Electronic Publication: 2025 Jan 13.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

A goldilocks computational protocol for inhibitor discovery targeting DNA damage responses including replication-repair functions.

Authors: Moiani D Tainer JA

Source: Frontiers in molecular biosciences [Front Mol Biosci] 2024 Nov 28; Vol. 11, pp. 1442267. Date of Electronic Publication: 2024 Nov 28 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101653173 Publication Model: eCollection Cited Medium: Print ISSN: 2296-889X (Print) Linking ISSN: 2296889X NLM ISO Abbreviation: Front Mol Biosci Subsets: PubMed not MEDLINE

HP1β recruits RING1A to ubiquitinate histone H2A for BRCA1-mediated resection of double-stand breaks.

Authors: Charaka V Pandita RK Tsai CL et al.

Source: IScience [iScience] 2025 Dec 30; Vol. 29 (2), pp. 114582. Date of Electronic Publication: 2025 Dec 30 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

APOL2 Stabilizes Ku80 to Confer NHEJ-Mediated Radioresistance in Gastric Cancer.

Authors: Zu D Bao Q He H et al.

Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Nov; Vol. 12 (44), pp. e06294. Date of Electronic Publication: 2025 Sep 15.

Publication Type: Journal Article

Journal Info: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer.

Authors: Fu J Ling J Li CF et al.

Source: Nature communications [Nat Commun] 2024 Apr 11; Vol. 15 (1), pp. 3149. Date of Electronic Publication: 2024 Apr 11.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Author Correction: Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology.

Authors: Filandr F Sarpe V Raval S et al.

Source: Nature communications [Nat Commun] 2024 Apr 02; Vol. 15 (1), pp. 2836. Date of Electronic Publication: 2024 Apr 02.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE; PubMed not MEDLINE

Information theory optimization of signals from small-angle scattering measurements.

Authors: Rambo RP Tainer JA

Source: Biophysical journal [Biophys J] 2025 Aug 05; Vol. 124 (15), pp. 2511-2522. Date of Electronic Publication: 2025 Jun 27.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability.

Authors: Provasek VE Bacolla A Rangaswamy S et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jul 25. Date of Electronic Publication: 2025 Jul 25.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Huntingtin preserves mitochondrial genome integrity in neurons, which is impaired in Huntington's disease.

Authors: Pradhan S Gaikwad S Tsai CL et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jul 24. Date of Electronic Publication: 2025 Jul 24.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology.

Authors: Filandr F Sarpe V Raval S et al.

Source: Nature communications [Nat Commun] 2024 Mar 11; Vol. 15 (1), pp. 2200. Date of Electronic Publication: 2024 Mar 11.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer.

Authors: Ye Z Xu S Shi Y et al.

Source: Nature communications [Nat Commun] 2024 Mar 08; Vol. 15 (1), pp. 2132. Date of Electronic Publication: 2024 Mar 08.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity.

Authors: Syed A Filandr F Patterson-Fortin J et al.

Source: Nucleic acids research [Nucleic Acids Res] 2023 Oct 13; Vol. 51 (18), pp. 9920-9937.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE