Search Results - "Valenstein, Max L."

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  1. 1

    Structural basis for the recruitment and selective phosphorylation of Akt by mTORC2.

    Authors: Taylor, Martin S. Chen, Maggie Hancock, Matthew et al.

    Source: Science. 3/5/2026, Vol. 391 Issue 6789, p1-21. 21p.

    Subjects: Protein kinase B, TOR proteins, Enzyme specificity, Cell communication, Protein structure, Drug target, Cellular signal transduction, Protein kinases

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  2. 2

    Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders.

    Authors: Yang, Jason Xu, Yunhan Ziehr, David R. et al.

    Source: Science. 7/17/2025, Vol. 389 Issue 6757, p1-20. 20p.

    Subjects: Transfer RNA, Neurodegeneration, Proteomics, RNA splicing, Trinucleotide repeats

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  3. 3

    Rag-Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathway.

    Authors: Valenstein, Max L. Lalgudi, Pranav V. Xin Gu et al.

    Source: Proceedings of the National Academy of Sciences of the United States of America. 8/27/2024, Vol. 121 Issue 35, p1-12. 17p.

    Subjects: N-terminal residues, Cell metabolism, Amino acids, Cellular signal transduction, Cell growth

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  4. 4

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  5. 5

    Structural basis for the dynamic regulation of mTORC1 by amino acids.

    Authors: Valenstein, Max L. Wranik, Maximilian Lalgudi, Pranav V. et al.

    Source: Nature. Aug2025, p1-8.

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  6. 6

    Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases.

    Authors: Kuang Shen Valenstein, Max L. Xin Gu et al.

    Source: Journal of Biological Chemistry. 2/22/2019, Vol. 294 Issue 8, p2970-2975. 6p.

    Subjects: Guanosine triphosphatase, Hydrolysis, Amino acids, Heterodimers, Immunoprecipitation

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  7. 7

    Formation of triple-helical structures by the 3'-end sequences of MALAT1 and MENß noncoding RNAs.

    Authors: Brown, Jessica A. Valenstein, Max L. Yario, Therese A. et al.

    Source: Proceedings of the National Academy of Sciences of the United States of America. 11/20/2012, Vol. 109 Issue 47, p19202-19207. 6p.

    Subjects: Helical structure, Nucleotide sequence, Non-coding RNA, Adenocarcinoma, Globin, Nucleotides, Gene expression

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  8. 8

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  9. 9

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  10. 10

    Amino acids and KLHL22 do not activate mTORC1 via DEPDC5 degradation.

    Authors: Valenstein ML Lalgudi PV Kedir JF et al.

    Source: Nature [Nature] 2025 Jan; Vol. 637 (8045), pp. E11-E14. Date of Electronic Publication: 2025 Jan 08.

    Publication Type: Letter; Comment

    Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE; In Process

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  11. 11

    Author Correction: Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila.

    Authors: Gu X Jouandin P Lalgudi PV et al.

    Source: Nature [Nature] 2022 Sep; Vol. 609 (7929), pp. E11.

    Publication Type: Published Erratum

    Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE; PubMed not MEDLINE

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  12. 12

    Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila.

    Authors: Gu X Jouandin P Lalgudi PV et al.

    Source: Nature [Nature] 2022 Aug; Vol. 608 (7921), pp. 209-216. Date of Electronic Publication: 2022 Jul 20.

    Publication Type: Journal Article

    Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

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  13. 13

    Structure of the nutrient-sensing hub GATOR2.

    Authors: Valenstein ML Rogala KB Lalgudi PV et al.

    Source: Nature [Nature] 2022 Jul; Vol. 607 (7919), pp. 610-616. Date of Electronic Publication: 2022 Jul 13.

    Publication Type: Journal Article

    Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

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  14. 14

    Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.

    Authors: Shen K Huang RK Brignole EJ et al.

    Source: Nature [Nature] 2018 Apr 05; Vol. 556 (7699), pp. 64-69. Date of Electronic Publication: 2018 Mar 28.

    Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

    Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

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