Search Results - "Winn SR"

Enhancement of therapeutic transgene insertion for treatment of murine phenylketonuria.

Authors: Martinez MA Richards DY Winn SR et al.

Source: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2025 Dec 26; Vol. 37 (1), pp. 102813. Date of Electronic Publication: 2025 Dec 26 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE

Therapeutic liver repopulation by transient acetaminophen selection of gene-modified hepatocytes.

Authors: Vonada A Tiyaboonchai A Nygaard S et al.

Source: Science translational medicine [Sci Transl Med] 2021 Jun 09; Vol. 13 (597).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Development of a porcine model of phenylketonuria with a humanized R408W mutation for gene editing.

Authors: Kaiser RA Carlson DF Allen KL et al.

Source: PloS one [PLoS One] 2021 Jan 25; Vol. 16 (1), pp. e0245831. Date of Electronic Publication: 2021 Jan 25 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Biochemical and behavioural profile of NTBC treated Tyrosinemie type 1 mice.

Authors: van Ginkel WG Winn SR Dudley S et al.

Source: Molecular genetics and metabolism [Mol Genet Metab] 2022 Sep-Oct; Vol. 137 (1-2), pp. 9-17. Date of Electronic Publication: 2022 Jul 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9805456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-7206 (Electronic) Linking ISSN: 10967192 NLM ISO Abbreviation: Mol Genet Metab Subsets: MEDLINE

Tetrahydrobiopterin treatment reduces brain L-Phe but only partially improves serotonin in hyperphenylalaninemic ENU1/2 mice.

Authors: Scherer T Allegri G Sarkissian CN et al.

Source: Journal of inherited metabolic disease [J Inherit Metab Dis] 2018 Jul; Vol. 41 (4), pp. 709-718. Date of Electronic Publication: 2018 Mar 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 7910918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2665 (Electronic) Linking ISSN: 01418955 NLM ISO Abbreviation: J Inherit Metab Dis Subsets: MEDLINE

Modeling the cognitive effects of diet discontinuation in adults with phenylketonuria (PKU) using pegvaliase therapy in PAH-deficient mice.

Authors: Winn SR Dudley S Scherer T et al.

Source: Molecular genetics and metabolism [Mol Genet Metab] 2022 May; Vol. 136 (1), pp. 46-64. Date of Electronic Publication: 2022 Mar 21.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9805456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-7206 (Electronic) Linking ISSN: 10967192 NLM ISO Abbreviation: Mol Genet Metab Subsets: MEDLINE

A novel Pah-exon1 deleted murine model of phenylalanine hydroxylase (PAH) deficiency.

Authors: Richards DY Winn SR Dudley S et al.

Source: Molecular genetics and metabolism [Mol Genet Metab] 2020 Nov; Vol. 131 (3), pp. 306-315. Date of Electronic Publication: 2020 Sep 30.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9805456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-7206 (Electronic) Linking ISSN: 10967192 NLM ISO Abbreviation: Mol Genet Metab Subsets: MEDLINE

Pharmacologic inhibition of L-tyrosine degradation ameliorates cerebral dopamine deficiency in murine phenylketonuria (PKU).

Authors: Harding CO Winn SR Gibson KM et al.

Source: Journal of inherited metabolic disease [J Inherit Metab Dis] 2014 Sep; Vol. 37 (5), pp. 735-43. Date of Electronic Publication: 2014 Feb 03.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 7910918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2665 (Electronic) Linking ISSN: 01418955 NLM ISO Abbreviation: J Inherit Metab Dis Subsets: MEDLINE

Recombinant vascular endothelial growth factor165 gene therapy improves anastomotic healing in an animal model of ischemic esophagogastrostomy.

Authors: Enestvedt CK Hosack L Hoppo T et al.

Source: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus [Dis Esophagus] 2012 Jul; Vol. 25 (5), pp. 456-64. Date of Electronic Publication: 2011 Sep 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 8809160 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1442-2050 (Electronic) Linking ISSN: 11208694 NLM ISO Abbreviation: Dis Esophagus Subsets: MEDLINE

AAV-Mediated CRISPR/Cas9 Gene Editing in Murine Phenylketonuria.

Authors: Richards DY Winn SR Dudley S et al.

Source: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2019 Dec 24; Vol. 17, pp. 234-245. Date of Electronic Publication: 2019 Dec 24 (Print Publication: 2020).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101624857 Publication Model: eCollection Cited Medium: Print ISSN: 2329-0501 (Print) Linking ISSN: 23290501 NLM ISO Abbreviation: Mol Ther Methods Clin Dev Subsets: PubMed not MEDLINE

Revascularization of rat fasciocutaneous flap using CROSSEAL with VEGF protein or plasmid DNA expressing VEGF.

Authors: McKnight CD Winn SR Gong X et al.

Source: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery [Otolaryngol Head Neck Surg] 2008 Aug; Vol. 139 (2), pp. 245-9.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8508176 Publication Model: Print Cited Medium: Print ISSN: 0194-5998 (Print) Linking ISSN: 01945998 NLM ISO Abbreviation: Otolaryngol Head Neck Surg Subsets: MEDLINE

Non-viral-mediated gene therapy approaches for bone repair.

Authors: Winn SR Chen JC Gong X et al.

Source: Orthodontics & craniofacial research [Orthod Craniofac Res] 2005 Aug; Vol. 8 (3), pp. 183-90.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Munksgaard Country of Publication: England NLM ID: 101144387 Publication Model: Print Cited Medium: Print ISSN: 1601-6335 (Print) Linking ISSN: 16016335 NLM ISO Abbreviation: Orthod Craniofac Res Subsets: MEDLINE

Establishing an immortalized human osteoprecursor cell line: OPC1.

Authors: Winn SR Randolph G Uludag H et al.

Source: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 1999 Oct; Vol. 14 (10), pp. 1721-33.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8610640 Publication Model: Print Cited Medium: Print ISSN: 0884-0431 (Print) Linking ISSN: 08840431 NLM ISO Abbreviation: J Bone Miner Res Subsets: MEDLINE

Blood phenylalanine reduction corrects CNS dopamine and serotonin deficiencies and partially improves behavioral performance in adult phenylketonuric mice.

Authors: Winn SR Scherer T Thöny B et al.

Source: Molecular genetics and metabolism [Mol Genet Metab] 2018 Jan; Vol. 123 (1), pp. 6-20. Date of Electronic Publication: 2017 Oct 19.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9805456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-7206 (Electronic) Linking ISSN: 10967192 NLM ISO Abbreviation: Mol Genet Metab Subsets: MEDLINE

High dose sapropterin dihydrochloride therapy improves monoamine neurotransmitter turnover in murine phenylketonuria (PKU).

Authors: Winn SR Scherer T Thöny B et al.

Source: Molecular genetics and metabolism [Mol Genet Metab] 2016 Jan; Vol. 117 (1), pp. 5-11. Date of Electronic Publication: 2015 Nov 26.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9805456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-7206 (Electronic) Linking ISSN: 10967192 NLM ISO Abbreviation: Mol Genet Metab Subsets: MEDLINE

The Influence of Vitamin D Metabolism on Gene Expression, Matrix Production and Mineralization During Osteoprecursor Cell-Based Bone Development.

Authors: Mason SS Kohles SS Winn SR et al.

Source: Journal of endocrinology and metabolism [J Endocrinol Metab] 2014 Apr; Vol. 4 (1-2), pp. 1-12.

Publication Type: Journal Article

Journal Info: Publisher: Elmer Press Country of Publication: Canada NLM ID: 101572696 Publication Model: Print Cited Medium: Print ISSN: 1923-2861 (Print) Linking ISSN: 19232861 NLM ISO Abbreviation: J Endocrinol Metab Subsets: PubMed not MEDLINE

Extrahepatic 25-Hydroxylation of Vitamin D3 in an Engineered Osteoblast Precursor Cell Line Exploring the Influence on Cellular Proliferation and Matrix Maturation during Bone Development.

Authors: Mason SS Kohles SS Winn SR et al.

Source: ISRN biomedical engineering [ISRN Biomed Eng] 2013; Vol. 2013. Date of Electronic Publication: 2013 Jun 04.

Publication Type: Journal Article

Journal Info: Publisher: [Hindawi Publishing Corporation] Country of Publication: United States NLM ID: 9918300877806676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2314-6346 (Electronic) Linking ISSN: 23146346 NLM ISO Abbreviation: ISRN Biomed Eng Subsets: PubMed not MEDLINE

Hepatocytes from wild-type or heterozygous donors are equally effective in achieving successful therapeutic liver repopulation in murine phenylketonuria (PKU).

Authors: Hamman KJ Winn SR Harding CO

Source: Molecular genetics and metabolism [Mol Genet Metab] 2011 Nov; Vol. 104 (3), pp. 235-40. Date of Electronic Publication: 2011 Aug 04.

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9805456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-7206 (Electronic) Linking ISSN: 10967192 NLM ISO Abbreviation: Mol Genet Metab Subsets: MEDLINE

Evaluating revascularization and flap survival using vascular endothelial growth factor in an irradiated rat model.

Authors: Angelos PC Winn SR Kaurin DS et al.

Source: Archives of facial plastic surgery [Arch Facial Plast Surg] 2011 May-Jun; Vol. 13 (3), pp. 185-9. Date of Electronic Publication: 2011 Jan 17.

Publication Type: Journal Article

Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 100883500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-3660 (Electronic) Linking ISSN: 15212491 NLM ISO Abbreviation: Arch Facial Plast Surg Subsets: MEDLINE

Three-Dimensional Culture of Cells and Matrix Biomolecules for Engineered Tissue Development and Biokinetics Model Validation.

Authors: Mason SS Kohles SS Zelick RD et al.

Source: Journal of nanotechnology in engineering and medicine [J Nanotechnol Eng Med] 2011 May 01; Vol. 2 (2), pp. 25001-25007.

Publication Type: Journal Article

Journal Info: Publisher: American Society of Mechanical Engineers Country of Publication: United States NLM ID: 101528062 Publication Model: Print Cited Medium: Print ISSN: 1949-2944 (Print) Linking ISSN: 19492944 NLM ISO Abbreviation: J Nanotechnol Eng Med Subsets: PubMed not MEDLINE