Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer. - Ichikawa, W.; Uetake, H.; Shirota, Y.; Yamada, H.; Takahashi, T.; Nihei, Z.; Sugihara, K.; Sasaki, Y.; Hirayama, R. (British Journal of Cancer, 2003)