17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex. - Harrison, David E.; Strong, Randy; Reifsnyder, Peter; Kumar, Navasuja; Fernandez, Elizabeth; Flurkey, Kevin; Javors, Martin A.; Lopez‐Cruzan, Marisa; Macchiarini, Francesca; Nelson, James F.; Markewych, Adrian; Bitto, Alessandro; et al. (Aging Cell, 2021)