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Covalent inhibitors of the PI3Kα RAS binding domain impair tumor growth driven by RAS and HER2.

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Title: Covalent inhibitors of the PI3Kα RAS binding domain impair tumor growth driven by RAS and HER2.
Authors: Klebba, Joseph E.1 (AUTHOR), Roy, Nilotpal1 (AUTHOR), Bernard, Steffen M.1 (AUTHOR), Grabow, Stephanie1 (AUTHOR), Hoffman, Melissa A.1 (AUTHOR), Miao, Hui1 (AUTHOR), Tamiya, Junko1 (AUTHOR), Wang, Jinwei1 (AUTHOR), Berry, Cynthia1 (AUTHOR), Esparza-Oros, Antonio1 (AUTHOR), Lin, Richard1 (AUTHOR), Liu, Yongsheng1 (AUTHOR), Pariollaud, Marie1 (AUTHOR), Parker, Holly1 (AUTHOR), Mochalkin, Igor1 (AUTHOR), Rana, Sareena2 (AUTHOR), Snead, Aaron N.1 (AUTHOR), Walton, Eric J.1 (AUTHOR), Wyrick, Taylor E.1 (AUTHOR), Aitichson, Erick1 (AUTHOR)
Source: Science. 11/13/2025, Vol. 390 Issue 6774, p702-709. 8p.
Database: Academic Search Ultimate
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  Data: <searchLink fieldCode="JN" term="%22Science%22">Science</searchLink>. 11/13/2025, Vol. 390 Issue 6774, p702-709. 8p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=189291583
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