The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML. - Haferlach, C.; Bacher, U.; Haferlach, T.; Dicker, F.; Alpermann, T.; Kern, W.; Schnittger, S. (Leukemia (08876924), 2011)