Intestinal Manometry Force Sensor for Robotic Capsule Endoscopy: An Acute, Multipatient In vivo Animal and Human Study.
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| Title: | Intestinal Manometry Force Sensor for Robotic Capsule Endoscopy: An Acute, Multipatient In vivo Animal and Human Study. |
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| Authors: | Francisco, Matthew M.1, Terry, Benjamin S.2, Schoen, Jonathan A.3, Rentschler, Mark E.4 |
| Source: | IEEE Transactions on Biomedical Engineering. May2016, Vol. 63 Issue 5, p943-951. 9p. |
| Subjects: | Tactile sensors, Capsule endoscopy, Diagnostic imaging, Biomedical engineering, Biomedical engineering instruments, Medical electronics, Medical equipment, Biomedical materials |
| Abstract: | Goal: Development of a new medical device class generally termed robotic capsule endoscopes (RCE) is currently being pursued by multiple research groups. These maneuverable devices will allow minimally invasive diagnosis and treatment of intestinal pathologies. While the intraluminal pressures related to the migrating motor complex (MMC) are well understood, no previous study has measured the active contact forces exerted by the human small bowel wall on a solid, or near solid bolus such as an RCE. Understanding and quantifying the active contact force are critical for the advancement of RCE technology. Methods: In this study, the authors develop a novel manometric contact force sensor for human studies and validate the feasibility of the design, sterilization method, and minimally invasive surgical procedure in a multianimal study, followed by a multihuman study. Results: Four porcine tests of the sensor were conducted. The mean porcine myenteric contact force measured using the new sensor is 1.20 ± 0.08 N·cm−1. The mean myenteric contact force recorded for all five human test subjects is 0.18 ± 0.33 N·cm−1. Conclusion: This study demonstrates the feasibility of operating an MMC force sensor in a live human with a minimally invasive surgical technique and presents force data necessary for RCE design. Significance: This study represents the first known myenteric contact force measurements on a solid bolus in the human small intestine. [ABSTRACT FROM AUTHOR] |
| Copyright of IEEE Transactions on Biomedical Engineering is the property of IEEE and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 114706564 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Intestinal Manometry Force Sensor for Robotic Capsule Endoscopy: An Acute, Multipatient In vivo Animal and Human Study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Francisco%2C+Matthew+M%2E%22">Francisco, Matthew M.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Terry%2C+Benjamin+S%2E%22">Terry, Benjamin S.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Schoen%2C+Jonathan+A%2E%22">Schoen, Jonathan A.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Rentschler%2C+Mark+E%2E%22">Rentschler, Mark E.</searchLink><relatesTo>4</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22IEEE+Transactions+on+Biomedical+Engineering%22">IEEE Transactions on Biomedical Engineering</searchLink>. May2016, Vol. 63 Issue 5, p943-951. 9p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Tactile+sensors%22">Tactile sensors</searchLink><br /><searchLink fieldCode="DE" term="%22Capsule+endoscopy%22">Capsule endoscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnostic+imaging%22">Diagnostic imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Biomedical+engineering%22">Biomedical engineering</searchLink><br /><searchLink fieldCode="DE" term="%22Biomedical+engineering+instruments%22">Biomedical engineering instruments</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+electronics%22">Medical electronics</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+equipment%22">Medical equipment</searchLink><br /><searchLink fieldCode="DE" term="%22Biomedical+materials%22">Biomedical materials</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Goal: Development of a new medical device class generally termed robotic capsule endoscopes (RCE) is currently being pursued by multiple research groups. These maneuverable devices will allow minimally invasive diagnosis and treatment of intestinal pathologies. While the intraluminal pressures related to the migrating motor complex (MMC) are well understood, no previous study has measured the active contact forces exerted by the human small bowel wall on a solid, or near solid bolus such as an RCE. Understanding and quantifying the active contact force are critical for the advancement of RCE technology. Methods: In this study, the authors develop a novel manometric contact force sensor for human studies and validate the feasibility of the design, sterilization method, and minimally invasive surgical procedure in a multianimal study, followed by a multihuman study. Results: Four porcine tests of the sensor were conducted. The mean porcine myenteric contact force measured using the new sensor is 1.20 ± 0.08 N·cm−1. The mean myenteric contact force recorded for all five human test subjects is 0.18 ± 0.33 N·cm−1. Conclusion: This study demonstrates the feasibility of operating an MMC force sensor in a live human with a minimally invasive surgical technique and presents force data necessary for RCE design. Significance: This study represents the first known myenteric contact force measurements on a solid bolus in the human small intestine. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of IEEE Transactions on Biomedical Engineering is the property of IEEE and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1109/TBME.2015.2479607 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 9 StartPage: 943 Subjects: – SubjectFull: Tactile sensors Type: general – SubjectFull: Capsule endoscopy Type: general – SubjectFull: Diagnostic imaging Type: general – SubjectFull: Biomedical engineering Type: general – SubjectFull: Biomedical engineering instruments Type: general – SubjectFull: Medical electronics Type: general – SubjectFull: Medical equipment Type: general – SubjectFull: Biomedical materials Type: general Titles: – TitleFull: Intestinal Manometry Force Sensor for Robotic Capsule Endoscopy: An Acute, Multipatient In vivo Animal and Human Study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Francisco, Matthew M. – PersonEntity: Name: NameFull: Terry, Benjamin S. – PersonEntity: Name: NameFull: Schoen, Jonathan A. – PersonEntity: Name: NameFull: Rentschler, Mark E. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May2016 Type: published Y: 2016 Identifiers: – Type: issn-print Value: 00189294 Numbering: – Type: volume Value: 63 – Type: issue Value: 5 Titles: – TitleFull: IEEE Transactions on Biomedical Engineering Type: main |
| ResultId | 1 |
