Magnetic resonance imaging of pulmonary nodules: accuracy in a granulomatous disease-endemic region.

Saved in:

Bibliographic Details
Title:	Magnetic resonance imaging of pulmonary nodules: accuracy in a granulomatous disease-endemic region.
Authors:	Henz Concatto, Natália^1,2 naticoncatto@hotmail.com, Watte, Guilherme³, Marchiori, Edson⁴, Irion, Klaus⁵, Felicetti, José⁶, Camargo, José⁶, Hochhegger, Bruno⁷, Felicetti, José Carlos⁸, Camargo, José Jesus⁸
Source:	European Radiology. Sep2016, Vol. 26 Issue 9, p2915-2920. 6p. 1 Black and White Photograph, 2 Charts.
Subjects:	Magnetic resonance imaging, Pulmonary nodules, Chest (Anatomy), Spinal cord, Diffusion magnetic resonance imaging, Computed tomography, Differential diagnosis, Granuloma, Lung tumors, Public health, Research evaluation, Spinal cord diseases, Solitary pulmonary nodule
Abstract:	Objective: To estimate the diagnostic accuracy of signal intensity of the lesion-to-spinal cord ratio (LSR) and apparent diffusion coefficient (ADC) in diffusion-weighted (DW) magnetic resonance imaging of pulmonary nodules suspicious for lung cancer in granulomatous lung disease-endemic regions.Methods: Forty-nine patients with indeterminate solitary pulmonary nodules detected by chest computed tomography and histopathologically confirmed diagnoses were included in the study. DW images were analysed semiquantitatively by focusing regions of interest on the lesion and spinal cord at the same level (for LSR calculation). ADCs were estimated from ratios of the two image signal intensities. Ratios of T1 and T2 signal intensity between nodules and muscle were calculated for comparison.Results: Mean ADCs ± standard deviations for lung cancer and benign lesions were 0.9 ± 0.2 and 1.3 ± 0.2 × 10(-3) mm(2)/s, respectively. Mean LSRs were 1.4 ± 0.3 for lung cancer and 1 ± 0.1 for benign lesions. ADCs and LSRs differed significantly between malignant and benign lesions (P < 0.001). Mean T2 signal intensity ratios also differed significantly between benign and malignant lesions (0.8 ± 0.2 vs. 1.6 ± 0.2; P < 0.05).Conclusions: DWI can help to differentiate malignant from benign lesions according to ADC and the LSR with good accuracy.Key Points: • DW imaging can help differentiate malignant from benign pulmonary nodules. • ADC and LSR signal intensities had only small overlap between malignant and benign pulmonary nodules. • Mean T2 signal intensity ratios differed significantly between benign and malignant lesions. [ABSTRACT FROM AUTHOR]
	Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database:	Engineering Source

Be the first to leave a comment!