Bibliographic Details
| Title: |
A near-infrared BSA coated DNA-AgNCs for cellular imaging. |
| Authors: |
Mu, Wei-Yu1, Yang, Rui1, Robertson, Akrofi1, Chen, Qiu-Yun1 chenqy@ujs.edu.cn |
| Source: |
Colloids & Surfaces B: Biointerfaces. Feb2018, Vol. 162, p427-431. 5p. |
| Subjects: |
Silver nanoparticles spectra, DNA spectra, Imaging systems in biology, Biosensors, Molecular self-assembly |
| Abstract: |
Near-infrared silver nanoclusters, have potential applications in the field of biosensing and biological imaging. However, less stability of most DNA-AgNCs limits their application. To obtain stable near-infrared fluorescence DNA-AgNCs for biological imaging, a new kind of near-infrared fluorescent DNA-Ag nanoclusters was constructed using the C3A rich aptamer as a synthesis template, GAG as the enhancer. In particular, a new DNA-AgNCs-Trp@BSA was obtained based on the self-assembly of bovine serum albumin (BSA) and tryptophan loaded DNA-AgNCs by hydrophobic interaction. This self-assembly method can be used to stabilize DNAn-Ag (n = 1–3) nanoclusters. Hence, the near-infrared fluorescence DNA-AgNCs-Trp@BSA was applied in cellular imaging of HepG-2 cells. [ABSTRACT FROM AUTHOR] |
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| Database: |
Engineering Source |
