Preparation and Applications of Organo-Silica Hybrid Mesoporous Silica Nanoparticles for the Co-Delivery of Drugs and Nucleic Acids.
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| Title: | Preparation and Applications of Organo-Silica Hybrid Mesoporous Silica Nanoparticles for the Co-Delivery of Drugs and Nucleic Acids. |
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| Authors: | Pontón, Iris1 (AUTHOR), Martí del Rio, Andrea1 (AUTHOR), Gómez Gómez, Marta1 (AUTHOR), Sánchez-García, David1 (AUTHOR) david.sanchez@iqs.edu |
| Source: | Nanomaterials (2079-4991). Dec2020, Vol. 10 Issue 12, p2466. 1p. |
| Subjects: | Mesoporous silica, Silica nanoparticles, Drug delivery systems, Nucleic acids, Cationic lipids |
| Abstract: | Combination therapies rely on the administration of more than one drug, with independent mechanisms of action, aiming to enhance the efficiency of the treatment. For an optimal performance, the implementation of such therapies requires the delivery of the correct combination of drugs to a specific cellular target. In this context, the use of nanoparticles (NP) as platforms for the co-delivery of multiple drugs is considered a highly promising strategy. In particular, mesoporous silica nanoparticles (MSN) have emerged as versatile building blocks to devise complex drug delivery systems (DDS). This review describes the design, synthesis, and application of MSNs to the delivery of multiple drugs including nucleic acids for combination therapies. [ABSTRACT FROM AUTHOR] |
| Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 147802308 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Preparation and Applications of Organo-Silica Hybrid Mesoporous Silica Nanoparticles for the Co-Delivery of Drugs and Nucleic Acids. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Pontón%2C+Iris%22">Pontón, Iris</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Martí+del+Rio%2C+Andrea%22">Martí del Rio, Andrea</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gómez+Gómez%2C+Marta%22">Gómez Gómez, Marta</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sánchez-García%2C+David%22">Sánchez-García, David</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> david.sanchez@iqs.edu</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Nanomaterials+%282079-4991%29%22">Nanomaterials (2079-4991)</searchLink>. Dec2020, Vol. 10 Issue 12, p2466. 1p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Mesoporous+silica%22">Mesoporous silica</searchLink><br /><searchLink fieldCode="DE" term="%22Silica+nanoparticles%22">Silica nanoparticles</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+delivery+systems%22">Drug delivery systems</searchLink><br /><searchLink fieldCode="DE" term="%22Nucleic+acids%22">Nucleic acids</searchLink><br /><searchLink fieldCode="DE" term="%22Cationic+lipids%22">Cationic lipids</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Combination therapies rely on the administration of more than one drug, with independent mechanisms of action, aiming to enhance the efficiency of the treatment. For an optimal performance, the implementation of such therapies requires the delivery of the correct combination of drugs to a specific cellular target. In this context, the use of nanoparticles (NP) as platforms for the co-delivery of multiple drugs is considered a highly promising strategy. In particular, mesoporous silica nanoparticles (MSN) have emerged as versatile building blocks to devise complex drug delivery systems (DDS). This review describes the design, synthesis, and application of MSNs to the delivery of multiple drugs including nucleic acids for combination therapies. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=147802308 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/nano10122466 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: 2466 Subjects: – SubjectFull: Mesoporous silica Type: general – SubjectFull: Silica nanoparticles Type: general – SubjectFull: Drug delivery systems Type: general – SubjectFull: Nucleic acids Type: general – SubjectFull: Cationic lipids Type: general Titles: – TitleFull: Preparation and Applications of Organo-Silica Hybrid Mesoporous Silica Nanoparticles for the Co-Delivery of Drugs and Nucleic Acids. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pontón, Iris – PersonEntity: Name: NameFull: Martí del Rio, Andrea – PersonEntity: Name: NameFull: Gómez Gómez, Marta – PersonEntity: Name: NameFull: Sánchez-García, David IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec2020 Type: published Y: 2020 Identifiers: – Type: issn-print Value: 20794991 Numbering: – Type: volume Value: 10 – Type: issue Value: 12 Titles: – TitleFull: Nanomaterials (2079-4991) Type: main |
| ResultId | 1 |
