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CFD analysis of the hyper-viscous effects on blood flow across abdominal aortic aneurysm in COVID patients: multiphysics approach.

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Title: CFD analysis of the hyper-viscous effects on blood flow across abdominal aortic aneurysm in COVID patients: multiphysics approach.
Authors: S., Shankar Narayan1,2 (AUTHOR) shankarsubramani3@gmail.com, Bhattacharjee, Anuradha2 (AUTHOR), Saha, Sunanda3 (AUTHOR)
Source: Computer Methods in Biomechanics & Biomedical Engineering. Apr2024, Vol. 27 Issue 5, p570-586. 17p.
Subjects: Abdominal aortic aneurysms, Solid mechanics, Cardiovascular system, Fluid mechanics, COVID-19, Blood flow, Pulsatile flow, Blood viscosity, Viscous flow
Abstract: Recent research has shown that individuals suffering from COVID-19 are accommodating an elevated level of blood viscosity due to the morphological changes in blood cells. As viscosity is a major flow parameter influencing the flow across a stenosis or an aneurysm, the examination of the significance of hyperviscosity in COVID patients is imperative in arterial pathologies. In this research, we have considered a patient-specific case in which the aneurysm is located along the abdominal aortal walls. Recent research on the side effects of COVID-19 voiced out the various effects on the circulatory system of humans. Also, as abdominal aneurysms exist very often among individuals, causing the death of 150–200 million every year, the hyper-viscous effects of blood on the flow across the diseased aorta are explored by considering the elevated viscosity levels. In vitro explorations contribute considerably to the clinical methods and treatments to be regarded. The objective of the present inquest is to research the flow field in aneurysmatic-COVID-affected patients considering the elastic nature of vessel walls, using the arbitrary Lagrangian-Eulerian approach. The study supports the various clinical findings that voiced the detrimental effects associated with blood hyperviscosity. The simulation results obtained, by solving the fluid mechanics' equations coupled with the solid mechanics' equations, employing a FEM solver suggest that the elevated stress imparted by the hyper-viscous flows on the walls of the aneurysmal aorta can trigger the fastening of the aneurysmal sac enlargement or rupture. [ABSTRACT FROM AUTHOR]
Copyright of Computer Methods in Biomechanics & Biomedical Engineering is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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DbLabel: Engineering Source
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PubTypeId: academicJournal
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  Data: CFD analysis of the hyper-viscous effects on blood flow across abdominal aortic aneurysm in COVID patients: multiphysics approach.
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  Data: <searchLink fieldCode="DE" term="%22Abdominal+aortic+aneurysms%22">Abdominal aortic aneurysms</searchLink><br /><searchLink fieldCode="DE" term="%22Solid+mechanics%22">Solid mechanics</searchLink><br /><searchLink fieldCode="DE" term="%22Cardiovascular+system%22">Cardiovascular system</searchLink><br /><searchLink fieldCode="DE" term="%22Fluid+mechanics%22">Fluid mechanics</searchLink><br /><searchLink fieldCode="DE" term="%22COVID-19%22">COVID-19</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+flow%22">Blood flow</searchLink><br /><searchLink fieldCode="DE" term="%22Pulsatile+flow%22">Pulsatile flow</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+viscosity%22">Blood viscosity</searchLink><br /><searchLink fieldCode="DE" term="%22Viscous+flow%22">Viscous flow</searchLink>
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  Data: Recent research has shown that individuals suffering from COVID-19 are accommodating an elevated level of blood viscosity due to the morphological changes in blood cells. As viscosity is a major flow parameter influencing the flow across a stenosis or an aneurysm, the examination of the significance of hyperviscosity in COVID patients is imperative in arterial pathologies. In this research, we have considered a patient-specific case in which the aneurysm is located along the abdominal aortal walls. Recent research on the side effects of COVID-19 voiced out the various effects on the circulatory system of humans. Also, as abdominal aneurysms exist very often among individuals, causing the death of 150–200 million every year, the hyper-viscous effects of blood on the flow across the diseased aorta are explored by considering the elevated viscosity levels. In vitro explorations contribute considerably to the clinical methods and treatments to be regarded. The objective of the present inquest is to research the flow field in aneurysmatic-COVID-affected patients considering the elastic nature of vessel walls, using the arbitrary Lagrangian-Eulerian approach. The study supports the various clinical findings that voiced the detrimental effects associated with blood hyperviscosity. The simulation results obtained, by solving the fluid mechanics' equations coupled with the solid mechanics' equations, employing a FEM solver suggest that the elevated stress imparted by the hyper-viscous flows on the walls of the aneurysmal aorta can trigger the fastening of the aneurysmal sac enlargement or rupture. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Computer Methods in Biomechanics & Biomedical Engineering is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1080/10255842.2023.2194474
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      – Code: eng
        Text: English
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        PageCount: 17
        StartPage: 570
    Subjects:
      – SubjectFull: Abdominal aortic aneurysms
        Type: general
      – SubjectFull: Solid mechanics
        Type: general
      – SubjectFull: Cardiovascular system
        Type: general
      – SubjectFull: Fluid mechanics
        Type: general
      – SubjectFull: COVID-19
        Type: general
      – SubjectFull: Blood flow
        Type: general
      – SubjectFull: Pulsatile flow
        Type: general
      – SubjectFull: Blood viscosity
        Type: general
      – SubjectFull: Viscous flow
        Type: general
    Titles:
      – TitleFull: CFD analysis of the hyper-viscous effects on blood flow across abdominal aortic aneurysm in COVID patients: multiphysics approach.
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            NameFull: S., Shankar Narayan
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            NameFull: Bhattacharjee, Anuradha
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            NameFull: Saha, Sunanda
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              M: 04
              Text: Apr2024
              Type: published
              Y: 2024
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